| # | % | |||||
|---|---|---|---|---|---|---|
| 51 | RTW INVESTMENTS, LP | 171,898 | 5,558,000 | 1.18% | ||
| 52 | JPMORGAN CHASE & CO | 187,500 | 6,062,000 | 1.29% | ||
| 53 | SABBY MANAGEMENT, LLC | 342,857 | 6,446,000 | 1.37% | ||
| 54 | DRIEHAUS CAPITAL MANAGEMENT LLC | 201,262 | 6,507,000 | 1.38% | ||
| 55 | UBS Group AG | 215,431 | 6,965,000 | 1.48% | ||
| 56 | Redmile Group, LLC | 218,718 | 7,071,000 | 1.50% | ||
| 57 | GILDER GAGNON HOWE & CO LLC | 297,053 | 9,604,000 | 2.04% | ||
| 58 | JENNISON ASSOCIATES LLC | 312,822 | 10,114,000 | 2.15% | ||
| 59 | BAKER BROS. ADVISORS LP | 400,000 | 12,932,000 | 2.75% | ||
| 60 | RA CAPITAL MANAGEMENT, L.P. | 457,142 | 14,779,000 | 3.14% | ||
| 61 | FORESITE CAPITAL MANAGEMENT III, LLC | 460,000 | 14,872,000 | 3.16% | ||
| 62 | VANGUARD GROUP INC | 503,659 | 16,284,000 | 3.46% | ||
| 63 | JANUS HENDERSON INVESTORS US LLC | 699,384 | 22,611,000 | 4.81% | ||
| 64 | PFM Health Sciences, LP | 703,987 | 22,760,000 | 4.84% | ||
| 65 | WELLINGTON MANAGEMENT GROUP LLP | 1,000,502 | 32,346,000 | 6.87% | ||
| 66 | DEERFIELD MANAGEMENT COMPANY, L.P. | 1,163,811 | 37,626,000 | 8.00% | ||
| 67 | PERCEPTIVE ADVISORS LLC | 1,186,630 | 38,363,000 | 8.15% | ||
| 68 | FMR LLC | 4,568,562 | 147,701,000 | 31.39% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
