| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BlackRock Finance, Inc. | 2,843,025 | 56,148,000 | 12.54% | ||
| 2 | FMR LLC | 2,272,494 | 44,882,000 | 10.02% | ||
| 3 | Bain Capital Public Equity Management, LLC | 1,759,961 | 34,759,000 | 7.76% | ||
| 4 | Redmile Group, LLC | 1,718,671 | 33,944,000 | 7.58% | ||
| 5 | PERCEPTIVE ADVISORS LLC | 1,371,186 | 27,080,000 | 6.05% | ||
| 6 | RTW INVESTMENTS, LP | 1,272,770 | 25,137,000 | 5.61% | ||
| 7 | JPMORGAN CHASE & CO | 1,226,835 | 24,230,000 | 5.41% | ||
| 8 | VANGUARD GROUP INC | 1,082,461 | 21,379,000 | 4.77% | ||
| 9 | CITADEL ADVISORS LLC | 926,176 | 18,292,000 | 4.09% | ||
| 10 | FRANKLIN RESOURCES INC | 888,200 | 17,542,000 | 3.92% | ||
| 11 | STATE STREET CORP | 880,844 | 17,399,000 | 3.89% | ||
| 12 | GMT CAPITAL CORP | 609,700 | 12,346,000 | 2.76% | ||
| 13 | Invesco Ltd. | 406,029 | 8,020,000 | 1.79% | ||
| 14 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 325,000 | 6,419,000 | 1.43% | ||
| 15 | MILLENNIUM MANAGEMENT LLC | 320,247 | 6,325,000 | 1.41% | ||
| 16 | Point72 Asset Management, L.P. | 313,586 | 6,193,000 | 1.38% | ||
| 17 | NORTHERN TRUST CORP | 304,184 | 6,008,000 | 1.34% | ||
| 18 | ASCEND CAPITAL, LLC | 286,988 | 5,669,000 | 1.27% | ||
| 19 | PFM Health Sciences, LP | 271,603 | 5,364,000 | 1.20% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 229,907 | 4,540,000 | 1.01% | ||
| 21 | Weiss Multi-Strategy Advisers LLC | 200,000 | 3,950,000 | 0.88% | ||
| 22 | DEUTSCHE BANK AG\ | 180,709 | 3,567,000 | 0.80% | ||
| 23 | Bank of New York Mellon Corp | 177,277 | 3,501,000 | 0.78% | ||
| 24 | ArchPoint Investors | 168,020 | 3,318,000 | 0.74% | ||
| 25 | VIVO CAPITAL, LLC | 164,403 | 3,247,000 | 0.73% | ||
| 26 | Artal Group S.A. | 160,000 | 3,160,000 | 0.71% | ||
| 27 | FIL Ltd | 150,879 | 2,980,000 | 0.67% | ||
| 28 | CASTLE HOOK PARTNERS LP | 150,000 | 2,963,000 | 0.66% | ||
| 29 | Laurion Capital Management LP | 123,028 | 2,430,000 | 0.54% | ||
| 30 | Cormorant Asset Management, LP | 120,000 | 2,370,000 | 0.53% | SH | |
| 31 | Mirae Asset Global Investments Co., Ltd. | 118,091 | 2,332,000 | 0.52% | ||
| 32 | GOLDMAN SACHS GROUP INC | 113,906 | 2,250,000 | 0.50% | ||
| 33 | Informed Momentum Co LLC | 113,821 | 2,248,000 | 0.50% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 97,695 | 1,930,000 | 0.43% | ||
| 35 | SCHONFELD STRATEGIC ADVISORS LLC | 75,000 | 1,481,000 | 0.33% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 74,175 | 1,465,000 | 0.33% | ||
| 37 | MORGAN STANLEY | 68,072 | 1,344,000 | 0.30% | ||
| 38 | BANK OF AMERICA CORP /DE/ | 52,782 | 1,042,000 | 0.23% | ||
| 39 | AQR CAPITAL MANAGEMENT LLC | 52,258 | 1,032,000 | 0.23% | ||
| 40 | AMERIPRISE FINANCIAL INC | 51,804 | 1,023,000 | 0.23% | ||
| 41 | Nationwide Fund Advisors | 49,074 | 969,000 | 0.22% | ||
| 42 | TEACHERS ADVISORS, LLC | 48,957 | 967,000 | 0.22% | ||
| 43 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 48,775 | 963,000 | 0.22% | ||
| 44 | VICTORY CAPITAL MANAGEMENT INC | 46,459 | 918,000 | 0.21% | ||
| 45 | Swiss National Bank | 42,600 | 841,000 | 0.19% | ||
| 46 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 40,935 | 808,000 | 0.18% | ||
| 47 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 40,000 | 790,000 | 0.18% | ||
| 48 | Endurant Capital Management LP | 36,000 | 711,000 | 0.16% | ||
| 49 | STRS OHIO | 35,000 | 691,000 | 0.15% | ||
| 50 | NEW YORK STATE COMMON RETIREMENT FUND | 29,900 | 591,000 | 0.13% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
