| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Bain Capital Public Equity Management, LLC | 2,494,359 | 46,270,000 | 13.63% | ||
| 2 | FMR LLC | 2,285,794 | 42,401,000 | 12.49% | ||
| 3 | PERCEPTIVE ADVISORS LLC | 1,282,286 | 23,786,000 | 7.01% | ||
| 4 | BlackRock Fund Advisors | 1,034,945 | 19,198,000 | 5.66% | ||
| 5 | JPMORGAN CHASE & CO | 999,747 | 18,546,000 | 5.46% | ||
| 6 | FRANKLIN RESOURCES INC | 973,200 | 18,053,000 | 5.32% | ||
| 7 | VANGUARD GROUP INC | 796,817 | 14,781,000 | 4.35% | ||
| 8 | BLACKROCK ADVISORS LLC | 709,444 | 13,160,000 | 3.88% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 552,022 | 10,240,000 | 3.02% | ||
| 10 | VIVO CAPITAL, LLC | 502,863 | 9,328,000 | 2.75% | ||
| 11 | PFM Health Sciences, LP | 498,585 | 9,249,000 | 2.72% | ||
| 12 | MILLENNIUM MANAGEMENT LLC | 460,114 | 8,535,000 | 2.51% | ||
| 13 | Invesco Ltd. | 360,745 | 6,692,000 | 1.97% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 354,480 | 6,576,000 | 1.94% | ||
| 15 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 350,000 | 6,493,000 | 1.91% | ||
| 16 | Weiss Multi-Strategy Advisers LLC | 325,204 | 6,033,000 | 1.78% | ||
| 17 | STATE STREET CORP | 307,820 | 5,711,000 | 1.68% | ||
| 18 | FIL Ltd | 302,198 | 5,606,000 | 1.65% | ||
| 19 | JENNISON ASSOCIATES LLC | 292,268 | 5,422,000 | 1.60% | ||
| 20 | QVT Financial LP | 250,104 | 4,639,000 | 1.37% | ||
| 21 | RTW INVESTMENTS, LP | 239,789 | 4,448,000 | 1.31% | ||
| 22 | AXA S.A. | 233,070 | 4,323,000 | 1.27% | ||
| 23 | NORTHERN TRUST CORP | 215,069 | 3,989,000 | 1.18% | ||
| 24 | Numina Capital Management, LLC | 185,471 | 3,440,000 | 1.01% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 165,397 | 3,068,000 | 0.90% | ||
| 26 | Informed Momentum Co LLC | 161,208 | 2,990,000 | 0.88% | ||
| 27 | Artal Group S.A. | 160,000 | 2,968,000 | 0.87% | ||
| 28 | Cormorant Asset Management, LP | 156,741 | 2,908,000 | 0.86% | ||
| 29 | Bank of New York Mellon Corp | 154,145 | 2,859,000 | 0.84% | ||
| 30 | Nicholas Investment Partners, LP | 98,723 | 1,832,000 | 0.54% | ||
| 31 | BlackRock Investment Management, LLC | 83,888 | 1,556,000 | 0.46% | ||
| 32 | CITADEL ADVISORS LLC | 77,220 | 1,432,000 | 0.42% | ||
| 33 | MORGAN STANLEY | 72,920 | 1,353,000 | 0.40% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 69,449 | 1,289,000 | 0.38% | ||
| 35 | DEUTSCHE BANK AG\ | 63,028 | 1,167,000 | 0.34% | ||
| 36 | RUSSELL INVESTMENTS GROUP, LTD. | 62,141 | 1,140,000 | 0.34% | ||
| 37 | TIAA CREF INVESTMENT MANAGEMENT LLC | 59,653 | 1,107,000 | 0.33% | ||
| 38 | AMERIPRISE FINANCIAL INC | 55,808 | 1,035,000 | 0.30% | ||
| 39 | BANK OF AMERICA CORP /DE/ | 50,783 | 942,000 | 0.28% | ||
| 40 | GRATICULE ASIA MACRO ADVISORS LLC | 49,150 | 912,000 | 0.27% | ||
| 41 | SABBY MANAGEMENT, LLC | 48,400 | 898,000 | 0.26% | ||
| 42 | NORGES BANK | 44,943 | 834,000 | 0.25% | ||
| 43 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 44,834 | 832,000 | 0.25% | ||
| 44 | Nationwide Fund Advisors | 42,675 | 792,000 | 0.23% | ||
| 45 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 41,775 | 775,000 | 0.23% | ||
| 46 | SCHONFELD STRATEGIC ADVISORS LLC | 40,000 | 742,000 | 0.22% | ||
| 47 | VICTORY CAPITAL MANAGEMENT INC | 35,890 | 666,000 | 0.20% | ||
| 48 | TEACHERS ADVISORS, LLC | 33,884 | 629,000 | 0.19% | ||
| 49 | CREDIT SUISSE AG/ | 33,187 | 616,000 | 0.18% | ||
| 50 | Swiss National Bank | 32,600 | 605,000 | 0.18% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
