| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 18,180,445 | 869,570,000 | 16.35% | ||
| 2 | Clearbridge Investments, LLC | 12,052,583 | 576,475,000 | 10.84% | ||
| 3 | VANGUARD GROUP INC | 9,052,966 | 433,004,000 | 8.14% | ||
| 4 | BAILLIE GIFFORD & CO | 8,415,156 | 402,498,000 | 7.57% | ||
| 5 | BB BIOTECH AG | 6,913,172 | 330,657,000 | 6.22% | ||
| 6 | WELLINGTON MANAGEMENT GROUP LLP | 5,995,932 | 286,787,000 | 5.39% | ||
| 7 | WADDELL & REED FINANCIAL INC | 5,742,800 | 274,678,000 | 5.16% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 3,135,136 | 149,954,000 | 2.82% | ||
| 9 | BlackRock Fund Advisors | 3,057,681 | 146,249,000 | 2.75% | ||
| 10 | STATE STREET CORP | 2,772,679 | 132,612,000 | 2.49% | ||
| 11 | OppenheimerFunds, Inc. | 2,723,506 | 130,266,000 | 2.45% | ||
| 12 | PRICE T ROWE ASSOCIATES INC /MD/ | 1,900,605 | 90,906,000 | 1.71% | ||
| 13 | PINNACLE ASSOCIATES LTD | 1,572,045 | 75,191,000 | 1.41% | ||
| 14 | WELLS FARGO & COMPANY/MN | 1,198,363 | 57,318,000 | 1.08% | ||
| 15 | FRANKLIN RESOURCES INC | 1,076,534 | 51,573,000 | 0.97% | ||
| 16 | NORGES BANK | 1,065,766 | 50,976,000 | 0.96% | ||
| 17 | FIRST TRUST ADVISORS LP | 949,834 | 45,431,000 | 0.85% | ||
| 18 | BANK OF AMERICA CORP /DE/ | 933,295 | 44,639,000 | 0.84% | ||
| 19 | ALTRINSIC GLOBAL ADVISORS LLC | 921,174 | 44,060,000 | 0.83% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 872,879 | 41,749,000 | 0.78% | ||
| 21 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 822,510 | 39,341,000 | 0.74% | ||
| 22 | Fiera Capital Corp | 772,059 | 36,928,000 | 0.69% | ||
| 23 | AMERICAN CENTURY COMPANIES INC | 716,107 | 34,251,000 | 0.64% | ||
| 24 | DEUTSCHE BANK AG\ | 710,620 | 33,986,000 | 0.64% | ||
| 25 | RAYMOND JAMES & ASSOCIATES | 698,562 | 33,412,000 | 0.63% | ||
| 26 | GOLDMAN SACHS GROUP INC | 692,617 | 33,128,000 | 0.62% | ||
| 27 | DOWLING & YAHNKE LLC | 675,843 | 32,326,000 | 0.61% | ||
| 28 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 664,600 | 31,788,000 | 0.60% | Put | |
| 29 | STIFEL FINANCIAL CORP | 594,193 | 28,435,000 | 0.53% | ||
| 30 | Bank of New York Mellon Corp | 518,690 | 24,809,000 | 0.47% | ||
| 31 | NORTHERN TRUST CORP | 511,088 | 24,445,000 | 0.46% | ||
| 32 | PFM Health Sciences, LP | 470,534 | 22,506,000 | 0.42% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 450,000 | 21,524,000 | 0.40% | Call | |
| 34 | RENAISSANCE TECHNOLOGIES LLC | 449,514 | 21,500,000 | 0.40% | ||
| 35 | SCOUT INVESTMENTS, INC. | 424,646 | 20,311,000 | 0.38% | ||
| 36 | Mitsubishi UFJ Trust & Banking Corp | 391,690 | 18,735,000 | 0.35% | ||
| 37 | NEW YORK STATE COMMON RETIREMENT FUND | 386,252 | 18,474,000 | 0.35% | ||
| 38 | TIAA CREF INVESTMENT MANAGEMENT LLC | 367,700 | 17,587,000 | 0.33% | ||
| 39 | Motley Fool Wealth Management, LLC | 333,604 | 15,956,000 | 0.30% | ||
| 40 | AXA S.A. | 319,819 | 15,297,000 | 0.29% | ||
| 41 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 309,275 | 14,793,000 | 0.28% | ||
| 42 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 307,483 | 14,708,000 | 0.28% | ||
| 43 | BANK OF NOVA SCOTIA | 300,000 | 14,349,000 | 0.27% | ||
| 44 | SICART ASSOCIATES LLC | 280,315 | 13,407,000 | 0.25% | ||
| 45 | Granahan Investment Management, LLC | 273,900 | 13,101,000 | 0.25% | ||
| 46 | Motley Fool Asset Management LLC | 259,000 | 12,388,000 | 0.23% | ||
| 47 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 250,139 | 11,964,000 | 0.22% | ||
| 48 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 223,800 | 10,704,000 | 0.20% | ||
| 49 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 221,535 | 10,596,000 | 0.20% | ||
| 50 | CREDIT SUISSE AG/ | 214,953 | 10,283,000 | 0.19% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
