| 1 |
GILDER GAGNON HOWE & CO LLC |
4,379,002 |
83,289,000 |
18.97% |
|
|
| 2 |
Capital World Investors |
2,433,000 |
46,276,000 |
10.54% |
|
|
| 3 |
Bank of New York Mellon Corp |
1,948,329 |
37,056,000 |
8.44% |
|
|
| 4 |
Novo Holdings A/S |
1,397,718 |
26,585,000 |
6.06% |
|
|
| 5 |
KINGDON CAPITAL MANAGEMENT, L.L.C. |
1,379,486 |
26,238,000 |
5.98% |
|
|
| 6 |
BlackRock Fund Advisors |
1,232,630 |
23,445,000 |
5.34% |
|
|
| 7 |
VANGUARD GROUP INC |
962,842 |
18,313,000 |
4.17% |
|
|
| 8 |
TPG Group Holdings (SBS) Advisors, Inc. |
936,507 |
17,812,000 |
4.06% |
|
|
| 9 |
WASATCH ADVISORS LP |
919,035 |
17,480,000 |
3.98% |
|
|
| 10 |
PEREGRINE CAPITAL MANAGEMENT INC /MN/ |
736,887 |
14,016,000 |
3.19% |
|
|
| 11 |
BlackRock Institutional Trust Company, N.A. |
683,076 |
12,992,000 |
2.96% |
|
|
| 12 |
WELLINGTON MANAGEMENT GROUP LLP |
678,226 |
12,900,000 |
2.94% |
|
|
| 13 |
SCHRODER INVESTMENT MANAGEMENT GROUP |
590,778 |
11,237,000 |
2.56% |
|
|
| 14 |
DRIEHAUS CAPITAL MANAGEMENT LLC |
449,707 |
8,553,000 |
1.95% |
|
|
| 15 |
STATE STREET CORP |
391,606 |
7,449,000 |
1.70% |
|
|
| 16 |
NORTHERN TRUST CORP |
338,642 |
6,442,000 |
1.47% |
|
|
| 17 |
ROYAL BANK OF CANADA |
265,055 |
5,041,000 |
1.15% |
|
|
| 18 |
Alyeska Investment Group, L.P. |
250,000 |
4,755,000 |
1.08% |
|
|
| 19 |
GEODE CAPITAL MANAGEMENT, LLC |
187,039 |
3,557,000 |
0.81% |
|
|
| 20 |
Allianz Asset Management GmbH |
162,687 |
3,094,000 |
0.70% |
|
|
| 21 |
GAM Holding AG |
130,500 |
2,482,000 |
0.57% |
|
|
| 22 |
JPMORGAN CHASE & CO |
125,822 |
2,393,000 |
0.55% |
|
|
| 23 |
AMERICAN CENTURY COMPANIES INC |
109,761 |
2,088,000 |
0.48% |
|
|
| 24 |
SUMMIT PARTNERS PUBLIC ASSET MANAGEMENT, LLC |
100,000 |
1,902,000 |
0.43% |
Call |
|
| 25 |
WELLS FARGO & COMPANY/MN |
99,670 |
1,896,000 |
0.43% |
|
|
| 26 |
BlackRock Investment Management, LLC |
99,002 |
1,883,000 |
0.43% |
|
|
| 27 |
MORGAN STANLEY |
96,773 |
1,841,000 |
0.42% |
|
|
| 28 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
96,084 |
1,828,000 |
0.42% |
|
|
| 29 |
WALL STREET ASSOCIATES |
84,700 |
1,611,000 |
0.37% |
|
|
| 30 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
83,891 |
1,596,000 |
0.36% |
|
|
| 31 |
BAMCO INC /NY/ |
74,000 |
1,407,000 |
0.32% |
|
|
| 32 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
70,974 |
1,350,000 |
0.31% |
|
|
| 33 |
GUGGENHEIM CAPITAL LLC |
69,759 |
1,326,000 |
0.30% |
|
|
| 34 |
Mirae Asset Global Investments Co., Ltd. |
65,730 |
1,250,000 |
0.28% |
|
|
| 35 |
MACQUARIE GROUP LTD |
63,485 |
1,207,000 |
0.27% |
|
|
| 36 |
BANK OF MONTREAL /CAN/ |
71,270 |
1,176,000 |
0.27% |
|
|
| 37 |
BARCLAYS PLC |
60,371 |
1,149,000 |
0.26% |
|
|
| 38 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
55,113 |
1,048,000 |
0.24% |
|
|
| 39 |
Raymond James Financial Services Advisors, Inc. |
52,850 |
1,005,000 |
0.23% |
|
|
| 40 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
49,800 |
947,000 |
0.22% |
Put |
|
| 41 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
47,100 |
896,000 |
0.20% |
Call |
|
| 42 |
Squarepoint Ops LLC |
47,033 |
895,000 |
0.20% |
|
|
| 43 |
MILLENNIUM MANAGEMENT LLC |
44,804 |
852,000 |
0.19% |
|
|
| 44 |
TEACHERS ADVISORS, LLC |
43,468 |
827,000 |
0.19% |
|
|
| 45 |
HIGHBRIDGE CAPITAL MANAGEMENT LLC |
38,996 |
741,000 |
0.17% |
|
|
| 46 |
RUSSELL INVESTMENTS GROUP, LTD. |
37,533 |
715,000 |
0.16% |
|
|
| 47 |
Informed Momentum Co LLC |
36,882 |
701,000 |
0.16% |
|
|
| 48 |
CITADEL ADVISORS LLC |
36,723 |
698,000 |
0.16% |
|
|
| 49 |
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
32,889 |
636,000 |
0.14% |
|
|
| 50 |
GOLDMAN SACHS GROUP INC |
33,319 |
634,000 |
0.14% |
|
|
