| 1 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
3,870,824 |
13,548,000 |
47.56% |
|
|
| 2 |
THB ASSET MANAGEMENT |
1,038,990 |
3,636,000 |
12.76% |
|
|
| 3 |
Opaleye Management Inc. |
985,900 |
3,451,000 |
12.11% |
|
|
| 4 |
PERKINS CAPITAL MANAGEMENT INC |
651,050 |
2,279,000 |
8.00% |
|
|
| 5 |
SOPHROSYNE CAPITAL LLC |
489,729 |
1,712,000 |
6.01% |
|
|
| 6 |
SABBY MANAGEMENT, LLC |
318,136 |
1,113,000 |
3.91% |
|
|
| 7 |
VANGUARD GROUP INC |
278,297 |
974,000 |
3.42% |
|
|
| 8 |
GOLDMAN SACHS GROUP INC |
144,100 |
504,000 |
1.77% |
|
|
| 9 |
DEUTSCHE BANK AG\ |
99,293 |
347,000 |
1.22% |
|
|
| 10 |
GEODE CAPITAL MANAGEMENT, LLC |
89,937 |
314,000 |
1.10% |
|
|
| 11 |
BlackRock Institutional Trust Company, N.A. |
70,813 |
248,000 |
0.87% |
|
|
| 12 |
Commonwealth Equity Services, Inc |
19,036 |
67,000 |
0.24% |
|
|
| 13 |
AMG National Trust Bank |
15,965 |
56,000 |
0.20% |
|
|
| 14 |
NORTHERN TRUST CORP |
13,546 |
47,000 |
0.16% |
|
|
| 15 |
BANK OF AMERICA CORP /DE/ |
8,484 |
30,000 |
0.11% |
|
|
| 16 |
ROYCE & ASSOCIATES LP |
8,000 |
28,000 |
0.10% |
|
|
| 17 |
REILLY FINANCIAL ADVISORS, LLC |
8,000 |
28,000 |
0.10% |
|
|
| 18 |
JNBA Financial Advisors |
7,775 |
27,000 |
0.09% |
|
|
| 19 |
MORGAN STANLEY |
6,042 |
21,000 |
0.07% |
|
|
| 20 |
FIFTH THIRD BANCORP |
3,300 |
12,000 |
0.04% |
|
|
| 21 |
BlackRock Investment Management, LLC |
3,278 |
11,000 |
0.04% |
|
|
| 22 |
B. Riley Wealth Management, Inc. |
3,000 |
10,000 |
0.04% |
|
|
| 23 |
MUFG Americas Holdings Corp |
2,430 |
9,000 |
0.03% |
|
|
| 24 |
MAGEE THOMSON INVESTMENT PARTNERS LLC |
1,705 |
5,000 |
0.02% |
|
|
| 25 |
AlphaMark Advisors, LLC |
1,200 |
4,000 |
0.01% |
|
|
| 26 |
ROYAL BANK OF CANADA |
463 |
2,000 |
0.01% |
|
|
| 27 |
ROBLE, BELKO & COMPANY, INC |
300 |
1,000 |
0.00% |
|
|
| 28 |
Tower Research Capital LLC (TRC) |
193 |
1,000 |
0.00% |
|
|
| 29 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
311 |
1,000 |
0.00% |
|
|
| 30 |
WELLS FARGO & COMPANY/MN |
2 |
0 |
0.00% |
|
|
| 31 |
UBS Group AG |
62 |
0 |
0.00% |
|
|
| 32 |
GLOBEFLEX CAPITAL L P |
83 |
0 |
0.00% |
|
|
