| 1 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
3,726,439 |
11,701,000 |
48.95% |
|
|
| 2 |
Opaleye Management Inc. |
2,120,000 |
6,657,000 |
27.85% |
|
|
| 3 |
PERKINS CAPITAL MANAGEMENT INC |
633,250 |
1,988,000 |
8.32% |
|
|
| 4 |
VANGUARD GROUP INC |
282,702 |
887,000 |
3.71% |
|
|
| 5 |
SOPHROSYNE CAPITAL LLC |
237,266 |
745,000 |
3.12% |
|
|
| 6 |
DEUTSCHE BANK AG\ |
192,752 |
605,000 |
2.53% |
|
|
| 7 |
GOLDMAN SACHS GROUP INC |
132,699 |
417,000 |
1.74% |
|
|
| 8 |
GEODE CAPITAL MANAGEMENT, LLC |
89,937 |
282,000 |
1.18% |
|
|
| 9 |
BlackRock Institutional Trust Company, N.A. |
59,695 |
187,000 |
0.78% |
|
|
| 10 |
Spectrum Asset Management, Inc. (NB/CA) |
25,000 |
79,000 |
0.33% |
|
|
| 11 |
Commonwealth Equity Services, Inc |
19,036 |
60,000 |
0.25% |
|
|
| 12 |
AMG National Trust Bank |
15,965 |
50,000 |
0.21% |
|
|
| 13 |
NORTHERN TRUST CORP |
14,845 |
47,000 |
0.20% |
|
|
| 14 |
VSR Financial Services, Inc. |
10,000 |
31,000 |
0.13% |
|
|
| 15 |
BANK OF AMERICA CORP /DE/ |
9,000 |
28,000 |
0.12% |
|
|
| 16 |
REILLY FINANCIAL ADVISORS, LLC |
8,000 |
25,000 |
0.10% |
|
|
| 17 |
JNBA Financial Advisors |
7,775 |
24,000 |
0.10% |
|
|
| 18 |
MORGAN STANLEY |
6,543 |
21,000 |
0.09% |
|
|
| 19 |
Financial Architects, Inc |
6,000 |
19,000 |
0.08% |
|
|
| 20 |
BlackRock Investment Management, LLC |
3,654 |
11,000 |
0.05% |
|
|
| 21 |
FIFTH THIRD BANCORP |
3,300 |
10,000 |
0.04% |
|
|
| 22 |
Tower Research Capital LLC (TRC) |
3,003 |
9,000 |
0.04% |
|
|
| 23 |
MUFG Americas Holdings Corp |
2,430 |
8,000 |
0.03% |
|
|
| 24 |
MAGEE THOMSON INVESTMENT PARTNERS LLC |
1,705 |
5,000 |
0.02% |
|
|
| 25 |
AlphaMark Advisors, LLC |
1,200 |
4,000 |
0.02% |
|
|
| 26 |
Walleye Trading LLC |
400 |
1,000 |
0.00% |
|
|
| 27 |
ROYAL BANK OF CANADA |
463 |
1,000 |
0.00% |
|
|
| 28 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
311 |
1,000 |
0.00% |
|
|
| 29 |
ROBLE, BELKO & COMPANY, INC |
300 |
1,000 |
0.00% |
|
|
| 30 |
WELLS FARGO & COMPANY/MN |
2 |
0 |
0.00% |
|
|
