| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,649,728 | 545,087,000 | 18.50% | ||
| 2 | AMERIPRISE FINANCIAL INC | 2,863,069 | 427,601,000 | 14.52% | ||
| 3 | Capital World Investors | 1,567,537 | 234,112,000 | 7.95% | ||
| 4 | Carmignac Gestion | 1,319,887 | 197,125,000 | 6.69% | ||
| 5 | ORBIMED ADVISORS LLC | 1,120,000 | 167,272,000 | 5.68% | ||
| 6 | VANGUARD GROUP INC | 1,089,655 | 162,740,000 | 5.52% | ||
| 7 | FIRST TRUST ADVISORS LP | 588,866 | 87,947,000 | 2.99% | ||
| 8 | BlackRock Fund Advisors | 435,983 | 65,114,000 | 2.21% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 415,376 | 62,036,000 | 2.11% | ||
| 10 | STATE STREET CORP | 408,976 | 61,084,000 | 2.07% | ||
| 11 | BANK OF AMERICA CORP /DE/ | 402,512 | 60,116,000 | 2.04% | ||
| 12 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 387,700 | 57,903,000 | 1.97% | Put | |
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 353,700 | 52,825,000 | 1.79% | Call | |
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 337,756 | 50,444,000 | 1.71% | ||
| 15 | JPMORGAN CHASE & CO | 315,997 | 47,194,000 | 1.60% | ||
| 16 | CREDIT AGRICOLE S A | 273,723 | 40,881,000 | 1.39% | ||
| 17 | BB BIOTECH AG | 255,719 | 38,192,000 | 1.30% | ||
| 18 | SECTORAL ASSET MANAGEMENT INC | 220,047 | 32,864,000 | 1.12% | ||
| 19 | DEUTSCHE BANK AG\ | 191,994 | 28,672,000 | 0.97% | ||
| 20 | HIGHFIELDS CAPITAL MANAGEMENT LP | 190,226 | 28,410,000 | 0.96% | ||
| 21 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 186,872 | 27,909,000 | 0.95% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 178,911 | 26,720,000 | 0.91% | ||
| 23 | ALTRINSIC GLOBAL ADVISORS LLC | 176,817 | 26,408,000 | 0.90% | ||
| 24 | COLUMBUS CIRCLE INVESTORS | 175,598 | 26,226,000 | 0.89% | ||
| 25 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 136,742 | 20,423,000 | 0.69% | ||
| 26 | D. E. Shaw & Co., Inc. | 129,700 | 19,371,000 | 0.66% | Put | |
| 27 | BLACKROCK ADVISORS LLC | 125,274 | 18,710,000 | 0.64% | ||
| 28 | NORGES BANK | 122,873 | 18,351,000 | 0.62% | ||
| 29 | GEODE CAPITAL MANAGEMENT, LLC | 109,119 | 16,296,000 | 0.55% | ||
| 30 | AXA S.A. | 95,990 | 14,336,000 | 0.49% | ||
| 31 | NORTHERN TRUST CORP | 68,096 | 10,171,000 | 0.35% | ||
| 32 | Bank of New York Mellon Corp | 67,500 | 10,081,000 | 0.34% | ||
| 33 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 64,644 | 9,654,000 | 0.33% | ||
| 34 | CREDIT SUISSE AG/ | 59,267 | 8,853,000 | 0.30% | ||
| 35 | ROYAL BANK OF CANADA | 55,183 | 8,240,000 | 0.28% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 54,353 | 8,118,000 | 0.28% | ||
| 37 | PICTET ASSET MANAGEMENT LTD | 52,894 | 7,900,000 | 0.27% | ||
| 38 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 52,058 | 7,775,000 | 0.26% | ||
| 39 | EMERALD ADVISERS, LLC | 48,742 | 7,280,000 | 0.25% | ||
| 40 | D. E. Shaw & Co., Inc. | 47,500 | 7,094,000 | 0.24% | Call | |
| 41 | CITIGROUP INC | 46,700 | 6,975,000 | 0.24% | Put | |
| 42 | VAN ECK ASSOCIATES CORP | 45,728 | 6,829,000 | 0.23% | ||
| 43 | GOLDMAN SACHS GROUP INC | 43,746 | 6,533,000 | 0.22% | ||
| 44 | GUGGENHEIM CAPITAL LLC | 40,824 | 6,097,000 | 0.21% | ||
| 45 | GOLDMAN SACHS GROUP INC | 38,700 | 5,780,000 | 0.20% | Call | |
| 46 | GOLDMAN SACHS GROUP INC | 38,500 | 5,750,000 | 0.20% | Put | |
| 47 | WELLS FARGO & COMPANY/MN | 38,324 | 5,724,000 | 0.19% | ||
| 48 | NEW YORK STATE COMMON RETIREMENT FUND | 37,400 | 5,586,000 | 0.19% | ||
| 49 | DIMENSIONAL FUND ADVISORS LP | 36,610 | 5,468,000 | 0.19% | ||
| 50 | South Dakota Investment Council | 36,200 | 5,406,000 | 0.18% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
