| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 3,610,846 | 871,586,000 | 18.97% | ||
| 2 | AMERIPRISE FINANCIAL INC | 1,496,079 | 361,123,000 | 7.86% | ||
| 3 | Carmignac Gestion | 1,324,607 | 319,734,000 | 6.96% | ||
| 4 | ORBIMED ADVISORS LLC | 1,120,000 | 270,346,000 | 5.88% | ||
| 5 | VANGUARD GROUP INC | 1,001,214 | 241,674,000 | 5.26% | ||
| 6 | Capital World Investors | 780,000 | 188,276,000 | 4.10% | ||
| 7 | FRED ALGER MANAGEMENT, LLC | 513,069 | 123,845,000 | 2.69% | ||
| 8 | FIRST TRUST ADVISORS LP | 487,459 | 117,663,000 | 2.56% | ||
| 9 | BlackRock Fund Advisors | 450,015 | 108,625,000 | 2.36% | ||
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 429,200 | 103,601,000 | 2.25% | Put | |
| 11 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 402,400 | 97,131,000 | 2.11% | Call | |
| 12 | BlackRock Institutional Trust Company, N.A. | 346,048 | 83,529,000 | 1.82% | ||
| 13 | JENNISON ASSOCIATES LLC | 345,366 | 83,364,000 | 1.81% | ||
| 14 | PRICE T ROWE ASSOCIATES INC /MD/ | 328,303 | 79,246,000 | 1.72% | ||
| 15 | JPMORGAN CHASE & CO | 291,674 | 70,405,000 | 1.53% | ||
| 16 | FRANKLIN RESOURCES INC | 275,991 | 66,619,000 | 1.45% | ||
| 17 | COLUMBIA WANGER ASSET MANAGEMENT LLC | 275,679 | 66,543,000 | 1.45% | ||
| 18 | STATE STREET CORP | 268,751 | 64,867,000 | 1.41% | ||
| 19 | COLUMBUS CIRCLE INVESTORS | 225,331 | 54,390,000 | 1.18% | ||
| 20 | CREDIT AGRICOLE S A | 224,568 | 54,206,000 | 1.18% | ||
| 21 | ALTRINSIC GLOBAL ADVISORS LLC | 190,670 | 46,024,000 | 1.00% | ||
| 22 | BB BIOTECH AG | 180,719 | 43,622,000 | 0.95% | ||
| 23 | WELLS FARGO & COMPANY/MN | 179,719 | 43,326,000 | 0.94% | ||
| 24 | SECTORAL ASSET MANAGEMENT INC | 177,647 | 42,880,000 | 0.93% | ||
| 25 | DEUTSCHE BANK AG\ | 176,321 | 42,558,000 | 0.93% | ||
| 26 | MANAGED ACCOUNT ADVISORS LLC | 174,549 | 42,133,000 | 0.92% | ||
| 27 | Alpha Wave Global, LP | 163,700 | 39,514,000 | 0.86% | ||
| 28 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 147,988 | 35,721,000 | 0.78% | ||
| 29 | BLACKROCK ADVISORS LLC | 131,173 | 31,663,000 | 0.69% | ||
| 30 | NORGES BANK | 128,155 | 30,934,000 | 0.67% | ||
| 31 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 127,598 | 30,800,000 | 0.67% | ||
| 32 | COMMERZBANK AKTIENGESELLSCHAFT /FI | 115,076 | 27,777,000 | 0.60% | ||
| 33 | BANK OF AMERICA CORP /DE/ | 102,226 | 24,676,000 | 0.54% | ||
| 34 | MORGAN STANLEY | 100,493 | 24,257,000 | 0.53% | ||
| 35 | TIAA CREF INVESTMENT MANAGEMENT LLC | 95,825 | 23,130,000 | 0.50% | ||
| 36 | FARALLON CAPITAL MANAGEMENT LLC | 91,200 | 22,014,000 | 0.48% | ||
| 37 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 87,000 | 21,000,000 | 0.46% | ||
| 38 | GEODE CAPITAL MANAGEMENT, LLC | 83,499 | 20,154,000 | 0.44% | ||
| 39 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 79,582 | 19,209,503 | 0.42% | ||
| 40 | CREDIT SUISSE AG/ | 75,757 | 18,285,000 | 0.40% | ||
| 41 | GLG LLC | 73,929 | 17,845,000 | 0.39% | ||
| 42 | AXA S.A. | 68,319 | 16,491,000 | 0.36% | ||
| 43 | EMERALD ADVISERS, LLC | 67,504 | 16,294,000 | 0.35% | ||
| 44 | Bank of New York Mellon Corp | 65,727 | 15,865,000 | 0.35% | ||
| 45 | RENAISSANCE TECHNOLOGIES LLC | 61,400 | 14,821,000 | 0.32% | ||
| 46 | D. E. Shaw & Co., Inc. | 59,000 | 14,241,000 | 0.31% | Put | |
| 47 | Cannell & Co. | 56,265 | 13,581,000 | 0.30% | ||
| 48 | Candriam S.C.A. | 56,000 | 13,517,000 | 0.29% | ||
| 49 | VAN ECK ASSOCIATES CORP | 53,759 | 12,976,000 | 0.28% | ||
| 50 | GUGGENHEIM CAPITAL LLC | 53,027 | 12,800,000 | 0.28% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
