| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAKER BROS. ADVISORS LP | 1,211,851 | 15,427,000 | 25.90% | ||
| 2 | FRANKLIN RESOURCES INC | 603,345 | 7,681,000 | 12.90% | ||
| 3 | DRIEHAUS CAPITAL MANAGEMENT LLC | 510,597 | 6,500,000 | 10.91% | ||
| 4 | Broadfin Capital, LLC | 510,500 | 6,499,000 | 10.91% | ||
| 5 | Visium Asset Management, LP | 298,804 | 3,804,000 | 6.39% | ||
| 6 | HIGHLAND CAPITAL MANAGEMENT LP | 266,271 | 3,390,000 | 5.69% | ||
| 7 | Cormorant Asset Management, LP | 246,877 | 3,143,000 | 5.28% | ||
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 190,000 | 2,419,000 | 4.06% | ||
| 9 | PERCEPTIVE ADVISORS LLC | 130,000 | 1,655,000 | 2.78% | ||
| 10 | BLACKROCK ADVISORS LLC | 125,200 | 1,594,000 | 2.68% | ||
| 11 | PUTNAM INVESTMENTS LLC | 115,156 | 1,466,000 | 2.46% | ||
| 12 | Alyeska Investment Group, L.P. | 100,290 | 1,277,000 | 2.14% | ||
| 13 | JENNISON ASSOCIATES LLC | 75,000 | 955,000 | 1.60% | ||
| 14 | DEERFIELD MANAGEMENT COMPANY, L.P. | 62,387 | 794,000 | 1.33% | ||
| 15 | FARALLON CAPITAL MANAGEMENT LLC | 50,000 | 637,000 | 1.07% | ||
| 16 | BlackRock Group LTD | 48,800 | 621,000 | 1.04% | ||
| 17 | SECTORAL ASSET MANAGEMENT INC | 30,000 | 382,000 | 0.64% | ||
| 18 | BlackRock Finance, Inc. | 26,000 | 331,000 | 0.56% | ||
| 19 | DEUTSCHE BANK AG\ | 24,683 | 314,000 | 0.53% | ||
| 20 | Sterling Capital Management LLC | 23,557 | 300,000 | 0.50% | ||
| 21 | Spark Investment Management LLC | 15,600 | 197,000 | 0.33% | ||
| 22 | JANE STREET GROUP, LLC | 12,489 | 159,000 | 0.27% | ||
| 23 | UBS AG | 916 | 12,000 | 0.02% | ||
| 24 | Tower Research Capital LLC (TRC) | 0 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
