| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | QVT Financial LP | 9,259,260 | 27,648,000 | 35.63% | ||
| 2 | ORBIMED ADVISORS LLC | 3,586,100 | 11,153,000 | 14.37% | ||
| 3 | BlackRock Institutional Trust Company, N.A. | 2,263,873 | 7,041,000 | 9.07% | ||
| 4 | VANGUARD GROUP INC | 1,930,420 | 6,003,000 | 7.74% | ||
| 5 | BlackRock Fund Advisors | 1,480,281 | 4,604,000 | 5.93% | ||
| 6 | NORTHERN TRUST CORP | 662,207 | 2,059,000 | 2.65% | ||
| 7 | Cormorant Asset Management, LP | 650,000 | 2,022,000 | 2.61% | ||
| 8 | STATE STREET CORP | 612,176 | 1,903,000 | 2.45% | ||
| 9 | TFS CAPITAL LLC | 491,137 | 1,527,000 | 1.97% | ||
| 10 | Artal Group S.A. | 410,130 | 1,276,000 | 1.64% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 377,030 | 1,173,000 | 1.51% | ||
| 12 | GEODE CAPITAL MANAGEMENT, LLC | 331,927 | 1,032,000 | 1.33% | ||
| 13 | Bank of New York Mellon Corp | 267,014 | 830,000 | 1.07% | ||
| 14 | TIAA CREF INVESTMENT MANAGEMENT LLC | 235,748 | 733,000 | 0.94% | ||
| 15 | MORGAN STANLEY | 235,114 | 731,000 | 0.94% | ||
| 16 | Bruce & Co., Inc. | 233,515 | 709,000 | 0.91% | ||
| 17 | GOLDMAN SACHS GROUP INC | 209,450 | 651,000 | 0.84% | ||
| 18 | BlackRock Investment Management, LLC | 187,264 | 582,000 | 0.75% | ||
| 19 | FMR LLC | 159,514 | 496,000 | 0.64% | ||
| 20 | BLAIR WILLIAM & CO/IL | 148,825 | 462,000 | 0.60% | ||
| 21 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 119,300 | 371,000 | 0.48% | Put | |
| 22 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 114,352 | 356,000 | 0.46% | ||
| 23 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 91,300 | 284,000 | 0.37% | ||
| 24 | TEACHERS ADVISORS, LLC | 88,434 | 275,000 | 0.35% | ||
| 25 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 74,453 | 232,000 | 0.30% | ||
| 26 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 62,642 | 195,000 | 0.25% | ||
| 27 | VOYA INVESTMENT MANAGEMENT LLC | 57,596 | 179,000 | 0.23% | ||
| 28 | WELLS FARGO & COMPANY/MN | 56,185 | 175,000 | 0.23% | ||
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 55,201 | 172,000 | 0.22% | ||
| 30 | RHUMBLINE ADVISERS | 54,500 | 169,000 | 0.22% | ||
| 31 | DENVER INVESTMENT ADVISORS LLC | 53,757 | 167,000 | 0.22% | ||
| 32 | METROPOLITAN LIFE INSURANCE CO/NY | 51,552 | 160,000 | 0.21% | ||
| 33 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 49,500 | 154,000 | 0.20% | Call | |
| 34 | Nine Chapters Capital Management LLC | 48,800 | 152,000 | 0.20% | ||
| 35 | BARCLAYS PLC | 50,403 | 151,000 | 0.19% | ||
| 36 | Nationwide Fund Advisors | 48,031 | 149,000 | 0.19% | ||
| 37 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 43,663 | 136,000 | 0.18% | ||
| 38 | AMERICAN INTERNATIONAL GROUP, INC. | 40,833 | 126,991 | 0.16% | ||
| 39 | BLACKROCK ADVISORS LLC | 39,132 | 122,000 | 0.16% | ||
| 40 | UBS AG | 36,700 | 114,000 | 0.15% | Call | |
| 41 | BANK OF AMERICA CORP /DE/ | 30,919 | 97,000 | 0.12% | ||
| 42 | JANE STREET GROUP, LLC | 27,458 | 85,000 | 0.11% | ||
| 43 | Rotella Capital Management, Inc. | 24,996 | 78,000 | 0.10% | ||
| 44 | ProShare Advisors LLC | 24,670 | 77,000 | 0.10% | ||
| 45 | PNC FINANCIAL SERVICES GROUP, INC. | 24,000 | 74,000 | 0.10% | ||
| 46 | Airain ltd | 22,438 | 70,000 | 0.09% | ||
| 47 | Aris Wealth Services, Inc. | 21,694 | 67,000 | 0.09% | ||
| 48 | Weiss Multi-Strategy Advisers LLC | 20,000 | 62,000 | 0.08% | ||
| 49 | CITADEL ADVISORS LLC | 18,424 | 57,000 | 0.07% | ||
| 50 | PRINCIPAL FINANCIAL GROUP INC | 16,372 | 51,000 | 0.07% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
