| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | QVT Financial LP | 3,662,932 | 18,791,000 | 15.72% | ||
| 2 | BlackRock Institutional Trust Company, N.A. | 2,285,727 | 11,726,000 | 9.81% | ||
| 3 | Avoro Capital Advisors LLC | 2,047,971 | 10,506,000 | 8.79% | ||
| 4 | VANGUARD GROUP INC | 2,007,058 | 10,296,000 | 8.61% | ||
| 5 | BlackRock Fund Advisors | 1,747,795 | 8,966,000 | 7.50% | ||
| 6 | MILLENNIUM MANAGEMENT LLC | 1,732,775 | 8,889,000 | 7.44% | ||
| 7 | Cormorant Asset Management, LP | 1,409,000 | 7,228,000 | 6.05% | ||
| 8 | STATE STREET CORP | 801,526 | 4,112,000 | 3.44% | ||
| 9 | NORTHERN TRUST CORP | 657,077 | 3,371,000 | 2.82% | ||
| 10 | Informed Momentum Co LLC | 621,454 | 3,188,000 | 2.67% | ||
| 11 | Candriam S.C.A. | 620,000 | 3,181,000 | 2.66% | ||
| 12 | Bank of New York Mellon Corp | 413,826 | 2,122,000 | 1.78% | ||
| 13 | Artal Group S.A. | 410,130 | 2,104,000 | 1.76% | ||
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 345,014 | 1,769,000 | 1.48% | ||
| 15 | BAILARD, INC. | 324,000 | 1,662,000 | 1.39% | ||
| 16 | Connor, Clark & Lunn Investment Management Ltd. | 238,200 | 1,222,000 | 1.02% | ||
| 17 | Bruce & Co., Inc. | 233,515 | 1,167,000 | 0.98% | ||
| 18 | TIAA CREF INVESTMENT MANAGEMENT LLC | 223,673 | 1,147,000 | 0.96% | ||
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 217,066 | 1,114,000 | 0.93% | ||
| 20 | AMERIPRISE FINANCIAL INC | 207,626 | 1,064,000 | 0.89% | ||
| 21 | AQR CAPITAL MANAGEMENT LLC | 204,600 | 1,049,000 | 0.88% | ||
| 22 | BlackRock Investment Management, LLC | 187,042 | 960,000 | 0.80% | ||
| 23 | PERCEPTIVE ADVISORS LLC | 181,117 | 929,000 | 0.78% | ||
| 24 | FMR LLC | 159,514 | 818,000 | 0.68% | ||
| 25 | RUSSELL FRANK CO/ | 154,956 | 795,000 | 0.67% | ||
| 26 | Nine Chapters Capital Management LLC | 146,200 | 750,000 | 0.63% | ||
| 27 | Numeric Investors LLC | 116,900 | 600,000 | 0.50% | ||
| 28 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 113,643 | 583,000 | 0.49% | ||
| 29 | ADVENT CAPITAL MANAGEMENT /DE/ | 108,700 | 558,000 | 0.47% | ||
| 30 | WELLS FARGO & COMPANY/MN | 101,583 | 522,000 | 0.44% | ||
| 31 | Spot Trading L.L.C | 97,100 | 498,000 | 0.42% | Put | |
| 32 | DEERE & CO | 96,500 | 495,000 | 0.41% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 91,300 | 469,000 | 0.39% | ||
| 34 | TEACHERS ADVISORS, LLC | 88,434 | 454,000 | 0.38% | ||
| 35 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 74,453 | 392,000 | 0.33% | ||
| 36 | MORGAN STANLEY | 76,210 | 391,000 | 0.33% | ||
| 37 | RHUMBLINE ADVISERS | 65,575 | 336,000 | 0.28% | ||
| 38 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 64,400 | 330,000 | 0.28% | Put | |
| 39 | TFS CAPITAL LLC | 61,700 | 317,000 | 0.27% | ||
| 40 | VOYA INVESTMENT MANAGEMENT LLC | 57,596 | 295,000 | 0.25% | ||
| 41 | GROUP ONE TRADING LLC | 55,610 | 285,000 | 0.24% | ||
| 42 | Zurcher Kantonalbank (Zurich Cantonalbank) | 53,954 | 277,000 | 0.23% | ||
| 43 | Nationwide Fund Advisors | 45,587 | 234,000 | 0.20% | ||
| 44 | BLAIR WILLIAM & CO/IL | 45,125 | 231,000 | 0.19% | ||
| 45 | ALLIANCEBERNSTEIN L.P. | 44,000 | 226,000 | 0.19% | ||
| 46 | BLACKROCK ADVISORS LLC | 43,103 | 221,000 | 0.18% | ||
| 47 | CREDIT SUISSE AG/ | 41,802 | 214,000 | 0.18% | ||
| 48 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 41,102 | 211,000 | 0.18% | ||
| 49 | AMERICAN INTERNATIONAL GROUP, INC. | 39,285 | 201,532 | 0.17% | ||
| 50 | Spot Trading L.L.C | 38,976 | 200,000 | 0.17% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
