| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 13,380,046 | 107,843,000 | 11.85% | ||
| 2 | Sarissa Capital Management LP | 12,000,000 | 96,720,000 | 10.63% | ||
| 3 | VANGUARD GROUP INC | 10,384,378 | 83,699,000 | 9.20% | ||
| 4 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 6,668,993 | 53,752,000 | 5.91% | ||
| 5 | Slate Path Capital LP | 6,620,000 | 53,357,000 | 5.86% | ||
| 6 | FRANKLIN RESOURCES INC | 5,153,627 | 41,538,000 | 4.57% | ||
| 7 | STATE STREET CORP | 4,847,909 | 39,070,000 | 4.29% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 4,579,777 | 36,913,000 | 4.06% | ||
| 9 | BlackRock Fund Advisors | 3,607,176 | 29,074,000 | 3.20% | ||
| 10 | Palo Alto Investors LP | 3,458,624 | 27,877,000 | 3.06% | ||
| 11 | RENAISSANCE TECHNOLOGIES LLC | 2,248,846 | 18,126,000 | 1.99% | ||
| 12 | NORGES BANK | 2,123,115 | 17,113,000 | 1.88% | ||
| 13 | BARCLAYS PLC | 1,802,400 | 14,420,000 | 1.58% | Put | |
| 14 | Opaleye Management Inc. | 1,670,000 | 13,460,000 | 1.48% | ||
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,554,500 | 12,529,000 | 1.38% | Call | |
| 16 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,551,300 | 12,504,000 | 1.37% | Put | |
| 17 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,381,480 | 11,135,000 | 1.22% | ||
| 18 | DEUTSCHE BANK AG\ | 1,288,405 | 10,383,000 | 1.14% | ||
| 19 | AMERIPRISE FINANCIAL INC | 1,273,505 | 10,263,000 | 1.13% | ||
| 20 | GENERAL AMERICAN INVESTORS CO INC | 1,200,000 | 9,672,000 | 1.06% | ||
| 21 | NORTHERN TRUST CORP | 986,531 | 7,952,000 | 0.87% | ||
| 22 | AQR CAPITAL MANAGEMENT LLC | 923,518 | 7,444,000 | 0.82% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 898,704 | 7,243,000 | 0.80% | ||
| 24 | BARCLAYS PLC | 813,300 | 6,506,000 | 0.72% | Call | |
| 25 | Bank of New York Mellon Corp | 721,605 | 5,816,000 | 0.64% | ||
| 26 | CITADEL ADVISORS LLC | 715,953 | 5,771,000 | 0.63% | ||
| 27 | GUGGENHEIM CAPITAL LLC | 677,369 | 5,459,000 | 0.60% | ||
| 28 | VAN ECK ASSOCIATES CORP | 669,593 | 5,397,000 | 0.59% | ||
| 29 | NOMURA HOLDINGS INC | 669,851 | 5,386,000 | 0.59% | ||
| 30 | Granite Point Capital Management, L.P. | 648,000 | 5,223,000 | 0.57% | ||
| 31 | PointState Capital LP | 600,000 | 4,836,000 | 0.53% | ||
| 32 | MORGAN STANLEY | 584,338 | 4,710,000 | 0.52% | ||
| 33 | AXA S.A. | 580,044 | 4,675,000 | 0.51% | ||
| 34 | A.R.T. Advisors, LLC | 568,559 | 4,582,000 | 0.50% | ||
| 35 | BNP Paribas Asset Management Holding S.A. | 521,917 | 4,207,000 | 0.46% | ||
| 36 | ROYCE & ASSOCIATES LP | 516,602 | 4,164,000 | 0.46% | ||
| 37 | Spot Trading L.L.C | 512,000 | 4,127,000 | 0.45% | Call | |
| 38 | UBS AG | 506,037 | 4,078,000 | 0.45% | ||
| 39 | SOROS FUND MANAGEMENT LLC | 500,000 | 4,030,000 | 0.44% | ||
| 40 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 495,164 | 3,991,000 | 0.44% | ||
| 41 | GOLDMAN SACHS GROUP INC | 401,565 | 3,237,000 | 0.36% | ||
| 42 | SELZ CAPITAL LLC | 400,000 | 3,224,000 | 0.35% | ||
| 43 | CREDIT SUISSE AG/ | 377,245 | 3,041,000 | 0.33% | ||
| 44 | GROUP ONE TRADING LLC | 375,573 | 3,027,000 | 0.33% | ||
| 45 | D. E. Shaw & Co., Inc. | 359,606 | 2,898,000 | 0.32% | ||
| 46 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 385,800 | 2,816,000 | 0.31% | ||
| 47 | Allianz Asset Management GmbH | 349,200 | 2,814,000 | 0.31% | ||
| 48 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 335,685 | 2,706,000 | 0.30% | ||
| 49 | COMMERZBANK AKTIENGESELLSCHAFT /FI | 327,874 | 2,643,000 | 0.29% | ||
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 304,539 | 2,455,000 | 0.27% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
