| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Sarissa Capital Management LP | 12,850,000 | 105,884,000 | 8.42% | ||
| 2 | VANGUARD GROUP INC | 11,173,568 | 92,071,000 | 7.32% | ||
| 3 | PUTNAM INVESTMENTS LLC | 10,556,693 | 86,987,000 | 6.92% | ||
| 4 | WESTFIELD CAPITAL MANAGEMENT CO LP | 9,312,635 | 76,736,000 | 6.10% | ||
| 5 | FMR LLC | 9,188,237 | 75,711,000 | 6.02% | ||
| 6 | BlackRock Fund Advisors | 8,363,038 | 68,911,000 | 5.48% | ||
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 7,400,000 | 60,976,000 | 4.85% | ||
| 8 | Camber Capital Management LP | 7,000,000 | 57,680,000 | 4.59% | ||
| 9 | DISCOVERY CAPITAL MANAGEMENT, LLC / CT | 5,842,050 | 48,138,000 | 3.83% | ||
| 10 | STATE STREET CORP | 5,710,519 | 47,053,000 | 3.74% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 4,899,564 | 40,372,000 | 3.21% | ||
| 12 | PointState Capital LP | 4,500,000 | 37,080,000 | 2.95% | ||
| 13 | Invesco Ltd. | 2,828,095 | 23,303,000 | 1.85% | ||
| 14 | RENAISSANCE TECHNOLOGIES LLC | 2,675,481 | 22,046,000 | 1.75% | ||
| 15 | Palo Alto Investors LP | 2,231,717 | 18,389,000 | 1.46% | ||
| 16 | NORTHERN TRUST CORP | 2,042,956 | 16,834,000 | 1.34% | ||
| 17 | BNP Paribas Asset Management Holding S.A. | 1,936,373 | 15,956,000 | 1.27% | ||
| 18 | OppenheimerFunds, Inc. | 1,852,920 | 15,268,000 | 1.21% | ||
| 19 | MILLENNIUM MANAGEMENT LLC | 1,644,953 | 13,554,000 | 1.08% | ||
| 20 | Opaleye Management Inc. | 1,500,000 | 12,360,000 | 0.98% | ||
| 21 | Alberta Investment Management Corp | 1,430,830 | 11,790,000 | 0.94% | ||
| 22 | NORGES BANK | 1,294,722 | 10,668,000 | 0.85% | ||
| 23 | HighVista Strategies LLC | 1,200,000 | 9,888,000 | 0.79% | ||
| 24 | GENERAL AMERICAN INVESTORS CO INC | 1,200,000 | 9,888,000 | 0.79% | ||
| 25 | DEUTSCHE BANK AG\ | 1,148,750 | 9,463,000 | 0.75% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 1,130,765 | 9,317,000 | 0.74% | ||
| 27 | AMERIPRISE FINANCIAL INC | 1,083,675 | 8,931,000 | 0.71% | ||
| 28 | GOLDMAN SACHS GROUP INC | 1,056,600 | 8,706,000 | 0.69% | Put | |
| 29 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,056,600 | 8,706,000 | 0.69% | Call | |
| 30 | Elk Creek Partners, LLC | 1,028,263 | 8,473,000 | 0.67% | ||
| 31 | ASCEND CAPITAL, LLC | 1,000,000 | 8,240,000 | 0.66% | ||
| 32 | Bank of New York Mellon Corp | 965,276 | 7,953,000 | 0.63% | ||
| 33 | COLUMBUS CIRCLE INVESTORS | 964,007 | 7,943,000 | 0.63% | ||
| 34 | CITY NATIONAL BANK | 934,052 | 7,697,000 | 0.61% | ||
| 35 | Granite Point Capital Management, L.P. | 900,000 | 7,416,000 | 0.59% | ||
| 36 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 814,300 | 6,710,000 | 0.53% | Put | |
| 37 | TIAA CREF INVESTMENT MANAGEMENT LLC | 806,573 | 6,646,000 | 0.53% | ||
| 38 | BALYASNY ASSET MANAGEMENT L.P. | 712,500 | 5,871,000 | 0.47% | ||
| 39 | GUGGENHEIM CAPITAL LLC | 712,320 | 5,870,000 | 0.47% | ||
| 40 | JS Capital Management LLC | 635,000 | 5,232,000 | 0.42% | ||
| 41 | CQS Cayman LP | 600,000 | 4,944,000 | 0.39% | ||
| 42 | CREDIT SUISSE AG/ | 593,580 | 4,891,000 | 0.39% | ||
| 43 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 561,274 | 4,625,000 | 0.37% | ||
| 44 | JPMORGAN CHASE & CO | 551,141 | 4,541,000 | 0.36% | ||
| 45 | PRICE MICHAEL F | 550,000 | 4,532,000 | 0.36% | ||
| 46 | BELLEVUE ASSET MANAGEMENT AG | 529,000 | 4,359,000 | 0.35% | ||
| 47 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 523,545 | 4,315,000 | 0.34% | ||
| 48 | GOLDMAN SACHS GROUP INC | 500,903 | 4,128,000 | 0.33% | ||
| 49 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 488,656 | 4,027,000 | 0.32% | ||
| 50 | BlackRock Investment Management, LLC | 456,151 | 3,759,000 | 0.30% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
