| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Sarissa Capital Management LP | 12,850,000 | 106,270,000 | 8.98% | ||
| 2 | VANGUARD GROUP INC | 11,537,938 | 95,419,000 | 8.06% | ||
| 3 | PUTNAM INVESTMENTS LLC | 9,325,187 | 77,119,000 | 6.51% | ||
| 4 | WESTFIELD CAPITAL MANAGEMENT CO LP | 9,163,460 | 75,782,000 | 6.40% | ||
| 5 | FMR LLC | 8,367,446 | 69,199,000 | 5.85% | ||
| 6 | BlackRock Fund Advisors | 8,279,306 | 68,470,000 | 5.78% | ||
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 6,750,000 | 55,823,000 | 4.72% | ||
| 8 | STATE STREET CORP | 6,088,120 | 50,350,000 | 4.25% | ||
| 9 | Camber Capital Management LP | 5,750,000 | 47,553,000 | 4.02% | ||
| 10 | DISCOVERY CAPITAL MANAGEMENT, LLC / CT | 5,305,742 | 43,878,000 | 3.71% | ||
| 11 | BlackRock Institutional Trust Company, N.A. | 4,664,568 | 38,576,000 | 3.26% | ||
| 12 | PointState Capital LP | 3,600,000 | 29,772,000 | 2.52% | ||
| 13 | Invesco Ltd. | 2,596,646 | 21,474,000 | 1.81% | ||
| 14 | Palo Alto Investors LP | 2,231,717 | 18,456,000 | 1.56% | ||
| 15 | RENAISSANCE TECHNOLOGIES LLC | 2,094,481 | 17,321,000 | 1.46% | ||
| 16 | NORTHERN TRUST CORP | 1,885,869 | 15,596,000 | 1.32% | ||
| 17 | OppenheimerFunds, Inc. | 1,852,920 | 15,324,000 | 1.29% | ||
| 18 | BNP Paribas Asset Management Holding S.A. | 1,732,795 | 14,330,000 | 1.21% | ||
| 19 | NORGES BANK | 1,543,444 | 12,764,000 | 1.08% | ||
| 20 | BALYASNY ASSET MANAGEMENT L.P. | 1,519,292 | 12,565,000 | 1.06% | ||
| 21 | Opaleye Management Inc. | 1,500,000 | 12,405,000 | 1.05% | ||
| 22 | Alberta Investment Management Corp | 1,254,286 | 10,373,000 | 0.88% | ||
| 23 | Elk Creek Partners, LLC | 1,247,917 | 10,320,000 | 0.87% | ||
| 24 | HighVista Strategies LLC | 1,200,000 | 9,924,000 | 0.84% | ||
| 25 | GENERAL AMERICAN INVESTORS CO INC | 1,200,000 | 9,924,000 | 0.84% | ||
| 26 | GEODE CAPITAL MANAGEMENT, LLC | 1,187,242 | 9,817,000 | 0.83% | ||
| 27 | Bank of New York Mellon Corp | 1,022,905 | 8,459,000 | 0.71% | ||
| 28 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 956,000 | 7,906,000 | 0.67% | Call | |
| 29 | GUGGENHEIM CAPITAL LLC | 845,615 | 6,993,000 | 0.59% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 818,604 | 6,770,000 | 0.57% | ||
| 31 | GOLDMAN SACHS GROUP INC | 800,478 | 6,620,000 | 0.56% | ||
| 32 | GOLDMAN SACHS GROUP INC | 788,200 | 6,518,000 | 0.55% | Put | |
| 33 | OXFORD ASSET MANAGEMENT LLP | 768,562 | 6,356,000 | 0.54% | ||
| 34 | DEUTSCHE BANK AG\ | 727,033 | 6,010,000 | 0.51% | ||
| 35 | Granite Point Capital Management, L.P. | 705,580 | 5,835,000 | 0.49% | ||
| 36 | TWO SIGMA INVESTMENTS, LP | 704,334 | 5,825,000 | 0.49% | ||
| 37 | COLUMBUS CIRCLE INVESTORS | 688,274 | 5,692,000 | 0.48% | ||
| 38 | AMERIPRISE FINANCIAL INC | 687,410 | 5,686,000 | 0.48% | ||
| 39 | MILLENNIUM MANAGEMENT LLC | 673,253 | 5,568,000 | 0.47% | ||
| 40 | CREDIT SUISSE AG/ | 648,796 | 5,365,000 | 0.45% | ||
| 41 | JS Capital Management LLC | 635,000 | 5,251,000 | 0.44% | ||
| 42 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 627,800 | 5,192,000 | 0.44% | Put | |
| 43 | MORGAN STANLEY | 586,754 | 4,852,000 | 0.41% | ||
| 44 | JPMORGAN CHASE & CO | 579,157 | 4,790,000 | 0.40% | ||
| 45 | BlackRock Investment Management, LLC | 567,997 | 4,697,000 | 0.40% | ||
| 46 | PRICE MICHAEL F | 550,000 | 4,549,000 | 0.38% | ||
| 47 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 540,391 | 4,470,000 | 0.38% | ||
| 48 | BELLEVUE ASSET MANAGEMENT AG | 495,000 | 4,094,000 | 0.35% | ||
| 49 | Rhenman & Partners Asset Management AB | 450,000 | 3,722,000 | 0.31% | ||
| 50 | BLACKROCK ADVISORS LLC | 449,654 | 3,719,000 | 0.31% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
