| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PUTNAM INVESTMENTS LLC | 15,675,422 | 97,971,000 | 11.89% | ||
| 2 | Sarissa Capital Management LP | 12,850,000 | 80,313,000 | 9.75% | ||
| 3 | VANGUARD GROUP INC | 12,145,786 | 75,912,000 | 9.21% | ||
| 4 | WESTFIELD CAPITAL MANAGEMENT CO LP | 9,493,458 | 59,334,000 | 7.20% | ||
| 5 | BlackRock Fund Advisors | 7,996,641 | 49,979,000 | 6.06% | ||
| 6 | STATE STREET CORP | 6,887,007 | 43,046,000 | 5.22% | ||
| 7 | FMR LLC | 6,359,246 | 39,745,000 | 4.82% | ||
| 8 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 5,612,361 | 35,077,000 | 4.26% | ||
| 9 | Camber Capital Management LP | 5,405,235 | 33,783,000 | 4.10% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 4,521,436 | 28,259,000 | 3.43% | ||
| 11 | PointState Capital LP | 4,250,000 | 26,563,000 | 3.22% | ||
| 12 | Palo Alto Investors LP | 2,257,217 | 14,108,000 | 1.71% | ||
| 13 | NORTHERN TRUST CORP | 2,094,590 | 13,091,000 | 1.59% | ||
| 14 | OppenheimerFunds, Inc. | 1,862,400 | 11,640,000 | 1.41% | ||
| 15 | NORGES BANK | 1,665,993 | 10,412,000 | 1.26% | ||
| 16 | Elk Creek Partners, LLC | 1,592,527 | 9,953,000 | 1.21% | ||
| 17 | Alberta Investment Management Corp | 1,418,866 | 8,868,000 | 1.08% | ||
| 18 | Opaleye Management Inc. | 1,310,000 | 8,188,000 | 0.99% | ||
| 19 | GENERAL AMERICAN INVESTORS CO INC | 1,200,000 | 7,500,000 | 0.91% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 1,199,668 | 7,497,000 | 0.91% | ||
| 21 | D. E. Shaw & Co., Inc. | 1,173,631 | 7,335,000 | 0.89% | ||
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,079,200 | 6,745,000 | 0.82% | Call | |
| 23 | BNP Paribas Asset Management Holding S.A. | 950,851 | 5,943,000 | 0.72% | ||
| 24 | Bank of New York Mellon Corp | 868,720 | 5,429,000 | 0.66% | ||
| 25 | HBK INVESTMENTS L P | 833,451 | 5,209,000 | 0.63% | ||
| 26 | PRICE MICHAEL F | 820,000 | 5,125,000 | 0.62% | ||
| 27 | HighVista Strategies LLC | 807,100 | 5,044,000 | 0.61% | ||
| 28 | RENAISSANCE TECHNOLOGIES LLC | 776,881 | 4,856,000 | 0.59% | ||
| 29 | TIAA CREF INVESTMENT MANAGEMENT LLC | 660,509 | 4,128,000 | 0.50% | ||
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 645,100 | 4,032,000 | 0.49% | ||
| 31 | JS Capital Management LLC | 630,000 | 3,938,000 | 0.48% | ||
| 32 | GUGGENHEIM CAPITAL LLC | 596,448 | 3,728,000 | 0.45% | ||
| 33 | Granite Point Capital Management, L.P. | 581,215 | 3,633,000 | 0.44% | ||
| 34 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 579,391 | 3,622,000 | 0.44% | ||
| 35 | BlackRock Investment Management, LLC | 563,474 | 3,522,000 | 0.43% | ||
| 36 | UBS Group AG | 504,463 | 3,153,000 | 0.38% | ||
| 37 | BELLEVUE ASSET MANAGEMENT AG | 495,000 | 3,094,000 | 0.38% | ||
| 38 | OXFORD ASSET MANAGEMENT LLP | 476,178 | 3,012,000 | 0.37% | ||
| 39 | Rhenman & Partners Asset Management AB | 430,000 | 2,688,000 | 0.33% | ||
| 40 | PDT Partners, LLC | 415,487 | 2,597,000 | 0.32% | ||
| 41 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 385,800 | 2,411,000 | 0.29% | ||
| 42 | GOLDMAN SACHS GROUP INC | 383,846 | 2,399,000 | 0.29% | ||
| 43 | ROYCE & ASSOCIATES LP | 375,352 | 2,346,000 | 0.28% | ||
| 44 | AMERIPRISE FINANCIAL INC | 372,160 | 2,326,000 | 0.28% | ||
| 45 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 314,000 | 1,963,000 | 0.24% | Put | |
| 46 | JPMORGAN CHASE & CO | 313,236 | 1,957,000 | 0.24% | ||
| 47 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 310,276 | 1,939,000 | 0.24% | ||
| 48 | TEACHERS ADVISORS, LLC | 305,401 | 1,909,000 | 0.23% | ||
| 49 | ALLIANCEBERNSTEIN L.P. | 309,785 | 1,809,000 | 0.22% | ||
| 50 | A.R.T. Advisors, LLC | 281,552 | 1,759,000 | 0.21% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
