| 1 |
WASATCH ADVISORS LP |
3,416,069 |
37,440,000 |
16.78% |
|
|
| 2 |
Aisling Capital LLC |
3,293,060 |
36,090,000 |
16.18% |
|
|
| 3 |
FMR LLC |
1,510,082 |
16,551,000 |
7.42% |
|
|
| 4 |
ONTARIO TEACHERS PENSION PLAN BOARD |
1,209,506 |
13,256,000 |
5.94% |
|
|
| 5 |
BlackRock Fund Advisors |
957,250 |
10,491,000 |
4.70% |
|
|
| 6 |
Broadfin Capital, LLC |
955,147 |
10,468,000 |
4.69% |
|
|
| 7 |
GOLDMAN SACHS GROUP INC |
726,117 |
7,958,000 |
3.57% |
|
|
| 8 |
Abingworth LLP |
714,285 |
7,829,000 |
3.51% |
|
|
| 9 |
VANGUARD GROUP INC |
614,022 |
6,729,000 |
3.02% |
|
|
| 10 |
Opaleye Management Inc. |
504,800 |
5,532,608 |
2.48% |
|
|
| 11 |
Grandeur Peak Global Advisors, LLC |
494,060 |
5,415,000 |
2.43% |
|
|
| 12 |
PointState Capital LP |
400,000 |
4,384,000 |
1.97% |
|
|
| 13 |
AXA S.A. |
360,863 |
3,955,000 |
1.77% |
|
|
| 14 |
CI Global Investments Inc. |
350,000 |
3,836,000 |
1.72% |
|
|
| 15 |
WILLIAM HARRIS INVESTORS INC |
326,396 |
3,577,000 |
1.60% |
|
|
| 16 |
Pier Capital, LLC |
325,904 |
3,572,000 |
1.60% |
|
|
| 17 |
C WorldWide Group Holding A/S |
318,000 |
3,434,000 |
1.54% |
|
|
| 18 |
WELLS FARGO & COMPANY/MN |
311,053 |
3,410,000 |
1.53% |
|
|
| 19 |
PUTNAM INVESTMENTS LLC |
300,500 |
3,293,000 |
1.48% |
|
|
| 20 |
STATE STREET CORP |
284,024 |
3,112,000 |
1.39% |
|
|
| 21 |
NORTHERN TRUST CORP |
238,091 |
2,609,000 |
1.17% |
|
|
| 22 |
BlackRock Institutional Trust Company, N.A. |
221,259 |
2,425,000 |
1.09% |
|
|
| 23 |
South Dakota Investment Council |
154,510 |
1,693,000 |
0.76% |
|
|
| 24 |
EVENTIDE ASSET MANAGEMENT, LLC |
153,800 |
1,686,000 |
0.76% |
|
|
| 25 |
Fiduciary Trust Co International of Pennsylvania |
138,467 |
1,518,000 |
0.68% |
|
|
| 26 |
GEODE CAPITAL MANAGEMENT, LLC |
119,229 |
1,306,000 |
0.59% |
|
|
| 27 |
Bank of New York Mellon Corp |
118,824 |
1,302,000 |
0.58% |
|
|
| 28 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
107,500 |
1,178,000 |
0.53% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
104,700 |
1,148,000 |
0.51% |
Put |
|
| 30 |
Weiss Multi-Strategy Advisers LLC |
100,000 |
1,096,000 |
0.49% |
|
|
| 31 |
PUBLIC EMPLOYEES RETIREMENT SYSTEM OF OHIO |
98,381 |
1,078,000 |
0.48% |
|
|
| 32 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
85,394 |
936,000 |
0.42% |
|
|
| 33 |
Allianz Asset Management GmbH |
75,681 |
829,000 |
0.37% |
|
|
| 34 |
GABELLI FUNDS LLC |
71,500 |
784,000 |
0.35% |
|
|
| 35 |
SABBY MANAGEMENT, LLC |
70,804 |
776,000 |
0.35% |
|
|
| 36 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
68,343 |
749,000 |
0.34% |
|
|
| 37 |
BlackRock Investment Management, LLC |
66,726 |
731,000 |
0.33% |
|
|
| 38 |
BANK OF MONTREAL /CAN/ |
55,120 |
604,000 |
0.27% |
|
|
| 39 |
MORGAN STANLEY |
51,458 |
563,000 |
0.25% |
|
|
| 40 |
Healthcare Value Capital, LLC |
50,000 |
548,000 |
0.25% |
|
|
| 41 |
OCONNOR, A Distinct Business Unit of UBS ASSET MANAGEMENT AMERICAS (LLC) |
50,000 |
548,000 |
0.25% |
|
|
| 42 |
LEVIN CAPITAL STRATEGIES, L.P. |
49,371 |
541,000 |
0.24% |
|
|
| 43 |
MILLENNIUM MANAGEMENT LLC |
48,998 |
537,000 |
0.24% |
|
|
| 44 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
42,185 |
462,000 |
0.21% |
|
|
| 45 |
UBS AG |
40,175 |
440,000 |
0.20% |
|
|
| 46 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
39,878 |
438,000 |
0.20% |
|
|
| 47 |
HIGHBRIDGE CAPITAL MANAGEMENT LLC |
37,907 |
415,000 |
0.19% |
|
|
| 48 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
37,200 |
408,000 |
0.18% |
Call |
|
| 49 |
WESTFIELD CAPITAL MANAGEMENT CO LP |
36,560 |
401,000 |
0.18% |
|
|
| 50 |
Piermont Capital Management Inc. |
32,270 |
354,000 |
0.16% |
|
|
