| # | % | |||||
|---|---|---|---|---|---|---|
| 101 | BlackRock Institutional Trust Company, N.A. | 1,318,191 | 17,202,000 | 3.16% | ||
| 102 | Tourbillon Capital Partners, L.P. | 1,526,343 | 19,919,000 | 3.66% | ||
| 103 | SECTORAL ASSET MANAGEMENT INC | 1,625,323 | 21,210,000 | 3.90% | ||
| 104 | JPMORGAN CHASE & CO | 1,692,811 | 22,091,000 | 4.06% | ||
| 105 | STATE STREET CORP | 1,826,471 | 23,837,000 | 4.38% | ||
| 106 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2,080,160 | 27,146,000 | 4.99% | ||
| 107 | Point72 Asset Management, L.P. | 2,569,636 | 33,534,000 | 6.16% | ||
| 108 | Palo Alto Investors LP | 3,892,199 | 50,793,000 | 9.33% | ||
| 109 | FMR LLC | 7,226,458 | 94,305,000 | 17.33% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.