| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | ProQuest Associates IV LLC | 4,668,763 | 43,278,000 | 28.36% | ||
| 2 | INVESTOR AB | 3,510,189 | 32,539,000 | 21.32% | ||
| 3 | Aisling Capital LLC | 2,983,797 | 27,660,000 | 18.12% | ||
| 4 | RA CAPITAL MANAGEMENT, L.P. | 1,458,792 | 13,523,000 | 8.86% | ||
| 5 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,396,880 | 12,949,000 | 8.48% | ||
| 6 | Foresite Capital Management II, LLC | 459,266 | 4,257,000 | 2.79% | ||
| 7 | ROYCE & ASSOCIATES LP | 455,282 | 4,220,000 | 2.77% | ||
| 8 | Sio Capital Management, LLC | 203,732 | 1,889,000 | 1.24% | ||
| 9 | Cormorant Asset Management, LP | 182,053 | 1,688,000 | 1.11% | ||
| 10 | Granahan Investment Management, LLC | 182,020 | 1,687,000 | 1.11% | ||
| 11 | Informed Momentum Co LLC | 135,728 | 1,258,000 | 0.82% | ||
| 12 | NEA Management Company, LLC | 133,488 | 1,237,000 | 0.81% | ||
| 13 | DEERFIELD MANAGEMENT COMPANY, L.P. | 105,000 | 973,000 | 0.64% | ||
| 14 | ACUTA CAPITAL PARTNERS, LLC | 80,959 | 750,000 | 0.49% | ||
| 15 | MARSHALL WACE, LLP | 80,821 | 749,000 | 0.49% | ||
| 16 | GOLDMAN SACHS GROUP INC | 64,352 | 597,000 | 0.39% | ||
| 17 | GEODE CAPITAL MANAGEMENT, LLC | 40,796 | 378,000 | 0.25% | ||
| 18 | RENAISSANCE TECHNOLOGIES LLC | 39,664 | 368,000 | 0.24% | ||
| 19 | HIGHLAND CAPITAL MANAGEMENT LP | 38,287 | 355,000 | 0.23% | ||
| 20 | MORGAN STANLEY | 35,112 | 325,000 | 0.21% | ||
| 21 | VANGUARD GROUP INC | 27,811 | 258,000 | 0.17% | ||
| 22 | RAYMOND JAMES & ASSOCIATES | 27,279 | 253,000 | 0.17% | ||
| 23 | CAXTON CORP | 26,736 | 248,000 | 0.16% | ||
| 24 | BlackRock Fund Advisors | 25,442 | 236,000 | 0.15% | ||
| 25 | Spark Investment Management LLC | 25,200 | 231,000 | 0.15% | ||
| 26 | MILLENNIUM MANAGEMENT LLC | 20,819 | 193,000 | 0.13% | ||
| 27 | NORTHERN TRUST CORP | 14,718 | 136,000 | 0.09% | ||
| 28 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 10,300 | 95,000 | 0.06% | ||
| 29 | Geduld E E | 10,000 | 93,000 | 0.06% | ||
| 30 | DEUTSCHE BANK AG\ | 7,937 | 73,000 | 0.05% | ||
| 31 | ROYAL BANK OF CANADA | 4,900 | 45,000 | 0.03% | ||
| 32 | UBS Group AG | 1,767 | 16,000 | 0.01% | ||
| 33 | BlackRock Investment Management, LLC | 1,507 | 14,000 | 0.01% | ||
| 34 | LADENBURG THALMANN FINANCIAL SERVICES INC. | 1,500 | 14,000 | 0.01% | ||
| 35 | WELLS FARGO & COMPANY/MN | 1,500 | 14,000 | 0.01% | ||
| 36 | BlackRock Institutional Trust Company, N.A. | 745 | 7,000 | 0.00% | ||
| 37 | BlackRock Group LTD | 631 | 6,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
