| 1 |
ProQuest Associates IV LLC |
5,062,363 |
35,335,000 |
21.17% |
|
|
| 2 |
INVESTOR AB |
3,510,189 |
24,501,000 |
14.68% |
|
|
| 3 |
Aisling Capital LLC |
2,275,455 |
15,883,000 |
9.52% |
|
|
| 4 |
VIVO CAPITAL, LLC |
2,019,955 |
14,099,000 |
8.45% |
|
|
| 5 |
CAXTON CORP |
1,774,319 |
12,385,000 |
7.42% |
|
|
| 6 |
ADAGE CAPITAL PARTNERS GP, L.L.C. |
1,700,000 |
11,866,000 |
7.11% |
|
|
| 7 |
FRANKLIN RESOURCES INC |
1,400,000 |
9,772,000 |
5.86% |
|
|
| 8 |
Invesco Ltd. |
1,258,481 |
8,784,000 |
5.26% |
|
|
| 9 |
PERCEPTIVE ADVISORS LLC |
1,020,011 |
7,120,000 |
4.27% |
|
|
| 10 |
Cormorant Asset Management, LP |
563,880 |
3,936,000 |
2.36% |
|
|
| 11 |
VANGUARD GROUP INC |
408,324 |
2,850,000 |
1.71% |
|
|
| 12 |
BlackRock Fund Advisors |
375,643 |
2,622,000 |
1.57% |
|
|
| 13 |
Granahan Investment Management, LLC |
372,326 |
2,599,000 |
1.56% |
|
|
| 14 |
ROYCE & ASSOCIATES LP |
322,582 |
2,252,000 |
1.35% |
|
|
| 15 |
DEERFIELD MANAGEMENT COMPANY, L.P. |
250,000 |
1,745,000 |
1.05% |
|
|
| 16 |
J. Goldman & Co LP |
184,977 |
1,291,000 |
0.77% |
|
|
| 17 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
165,334 |
1,154,000 |
0.69% |
|
|
| 18 |
NORTHERN TRUST CORP |
141,199 |
986,000 |
0.59% |
|
|
| 19 |
STATE STREET CORP |
139,618 |
976,000 |
0.58% |
|
|
| 20 |
NEA Management Company, LLC |
133,488 |
932,000 |
0.56% |
|
|
| 21 |
GEODE CAPITAL MANAGEMENT, LLC |
114,079 |
796,000 |
0.48% |
|
|
| 22 |
BlackRock Institutional Trust Company, N.A. |
98,884 |
690,000 |
0.41% |
|
|
| 23 |
Bank of New York Mellon Corp |
62,188 |
434,000 |
0.26% |
|
|
| 24 |
HAMILTON LANE ADVISORS LLC |
55,385 |
387,000 |
0.23% |
|
|
| 25 |
BlackRock Investment Management, LLC |
45,537 |
318,000 |
0.19% |
|
|
| 26 |
NEEDHAM INVESTMENT MANAGEMENT LLC |
45,000 |
314,000 |
0.19% |
|
|
| 27 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
41,054 |
287,000 |
0.17% |
|
|
| 28 |
First Light Asset Management, LLC |
37,429 |
261,000 |
0.16% |
|
|
| 29 |
COMMONWEALTH OF PENNSYLVANIA PUBLIC SCHOOL EMPLS RETRMT SYS |
30,769 |
215,000 |
0.13% |
|
|
| 30 |
PRICE T ROWE ASSOCIATES INC /MD/ |
27,730 |
194,000 |
0.12% |
|
|
| 31 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
27,734 |
194,000 |
0.12% |
|
|
| 32 |
AlpInvest Partners B.V. |
27,693 |
193,000 |
0.12% |
|
|
| 33 |
RICE HALL JAMES & ASSOCIATES, LLC |
25,631 |
179,000 |
0.11% |
|
|
| 34 |
PURA VIDA INVESTMENTS, LLC |
24,900 |
174,000 |
0.10% |
|
|
| 35 |
HIGHLAND CAPITAL MANAGEMENT LP |
24,173 |
169,000 |
0.10% |
|
|
| 36 |
RENAISSANCE TECHNOLOGIES LLC |
20,700 |
144,000 |
0.09% |
|
|
| 37 |
TEACHERS ADVISORS, LLC |
19,401 |
135,000 |
0.08% |
|
|
| 38 |
BOOTHBAY FUND MANAGEMENT, LLC |
14,724 |
103,000 |
0.06% |
|
|
| 39 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
13,462 |
94,000 |
0.06% |
|
|
| 40 |
TFS CAPITAL LLC |
10,393 |
73,000 |
0.04% |
|
|
| 41 |
NEW YORK STATE COMMON RETIREMENT FUND |
9,400 |
66,000 |
0.04% |
|
|
| 42 |
GLENMEDE TRUST CO NA |
9,323 |
65,000 |
0.04% |
|
|
| 43 |
Nationwide Fund Advisors |
7,976 |
56,000 |
0.03% |
|
|
| 44 |
MORGAN STANLEY |
8,021 |
55,000 |
0.03% |
|
|
| 45 |
AMERICAN INTERNATIONAL GROUP, INC. |
7,655 |
53,432 |
0.03% |
|
|
| 46 |
ROYAL BANK OF CANADA |
4,900 |
34,000 |
0.02% |
|
|
| 47 |
BLACKROCK ADVISORS LLC |
4,444 |
31,000 |
0.02% |
|
|
| 48 |
WELLS FARGO & COMPANY/MN |
4,481 |
31,000 |
0.02% |
|
|
| 49 |
DEUTSCHE BANK AG\ |
2,140 |
14,000 |
0.01% |
|
|
| 50 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
854 |
6,000 |
0.00% |
|
|
