| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | SANGAMO BIOSCIENCES INCORPORATED | 6,000,000 | 94,080,000 | 9.52% | Call | |
| 2 | ACHILLION PHARMACEUTICALS INC COM | 8,207,530 | 80,926,000 | 8.19% | ||
| 3 | DYAX CORP COM CVR | 4,207,594 | 70,498,000 | 7.13% | ||
| 4 | BIOCRYST PHARMACEUTICALS | 6,926,617 | 62,547,000 | 6.33% | ||
| 5 | REGULUS THERAPEUTICS INC | 3,590,688 | 60,826,000 | 6.15% | ||
| 6 | Dicerna Pharmaceuticals | 2,428,571 | 58,359,000 | 5.90% | ||
| 7 | DYNAVAX TECHNOLOGIES CORP | 2,600,000 | 58,318,000 | 5.90% | ||
| 8 | TG THERAPEUTICS INC COM | 3,125,149 | 48,377,000 | 4.89% | ||
| 9 | COHERUS BIOSCIENCES INC COM | 1,555,355 | 47,563,000 | 4.81% | ||
| 10 | Tekmira Pharmaceuticals Corp. | 2,714,800 | 47,400,000 | 4.80% | ||
| 11 | XENCOR INC COM | 2,149,423 | 32,929,000 | 3.33% | ||
| 12 | ZAFGEN INC COM | 732,960 | 29,033,000 | 2.94% | ||
| 13 | BLUEBIRD BIO INCORPORATED | 200,379 | 24,200,000 | 2.45% | ||
| 14 | ZS PHARMA INC | 564,483 | 23,753,000 | 2.40% | ||
| 15 | SANGAMO BIOSCIENCES INCORPORATED | 1,220,209 | 19,133,000 | 1.94% | ||
| 16 | Ascendis Pharma | 1,023,652 | 17,760,000 | 1.80% | ||
| 17 | JUNO THERAPEUTICS INCORPORATED | 280,000 | 16,985,000 | 1.72% | ||
| 18 | OMEROS CORP | 749,000 | 16,500,000 | 1.67% | ||
| 19 | Proteon Therapeutics | 1,250,000 | 14,538,000 | 1.47% | ||
| 20 | Agile Therapeutics, Inc. | 1,458,792 | 13,523,000 | 1.37% | ||
| 21 | NOVAVAX INC COM | 1,431,232 | 11,836,000 | 1.20% | ||
| 22 | THERAPEUTICSMD INC | 1,680,395 | 10,166,000 | 1.03% | ||
| 23 | ARRAY BIOPHARMA INC COM | 1,357,584 | 10,005,000 | 1.01% | ||
| 24 | CONCERT PHARMACEUTICALS INC COM | 660,000 | 9,996,000 | 1.01% | ||
| 25 | Orexigen Therapeutics, Inc. | 1,186,229 | 9,288,000 | 0.94% | ||
| 26 | TENAX THERAPEUTICS INC COM | 2,670,300 | 8,705,000 | 0.88% | ||
| 27 | TREVENA INC | 1,325,407 | 8,642,000 | 0.87% | ||
| 28 | SUCAMPO PHARMACEUTICALS INC | 450,000 | 7,002,000 | 0.71% | ||
| 29 | AKEBIA THERAPEUTICS INC | 597,363 | 6,637,000 | 0.67% | ||
| 30 | Vical Inc | 7,024,274 | 6,637,000 | 0.67% | ||
| 31 | AURINIA PHARMACEUTICALS INC | 1,504,776 | 6,561,000 | 0.66% | ||
| 32 | SCYNEXIS INC | 789,097 | 6,550,000 | 0.66% | ||
| 33 | BELLICUM PHARMACEUTICALS INC COM | 225,000 | 5,213,000 | 0.53% | ||
| 34 | AURIS MED HLDG AG | 940,000 | 5,029,000 | 0.51% | ||
| 35 | VERSARTIS INC COM | 231,267 | 4,248,000 | 0.43% | ||
| 36 | TROVAGENE INC COM NEW | 594,200 | 4,047,000 | 0.41% | ||
| 37 | BIOTA PHARMACEUTIALS INC COM | 1,403,853 | 3,229,000 | 0.33% | ||
| 38 | ROCKWELL MED INC COM | 250,207 | 2,735,000 | 0.28% | ||
| 39 | T2 BIOSYSTEMS INC | 138,002 | 2,142,000 | 0.22% | ||
| 40 | OCERA THERAPEUTICS INC | 417,476 | 1,966,000 | 0.20% | ||
| 41 | ONCOTHYREON INC COM N/C EFF 6/ | 1,165,765 | 1,900,000 | 0.19% | ||
| 42 | AGIOS PHARMACEUTICALS INC | 17,600 | 1,660,000 | 0.17% | ||
| 43 | NEWLINK GENETICS CORP | 30,000 | 1,641,000 | 0.17% | ||
| 44 | PTC THERAPEUTICS INC | 25,800 | 1,570,000 | 0.16% | ||
| 45 | SANOFI SPOND FUNSPONSORED ADR | 116,400 | 1,383,000 | 0.14% | ||
| 46 | REPLIGEN CORP COM | 45,000 | 1,366,000 | 0.14% | ||
| 47 | TESARO INC | 23,500 | 1,349,000 | 0.14% | ||
| 48 | ALKERMES PLC SHS | 19,200 | 1,171,000 | 0.12% | ||
| 49 | WAFERGEN BIO-SYSTEMS INC | 255,400 | 1,157,000 | 0.12% | ||
| 50 | REGENERON PHARMACEUTICALS | 2,450 | 1,106,000 | 0.11% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001144204-15-031600, filed 2015.05.15).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
