| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Tower Research Capital LLC (TRC) | 579 | 5,000 | 0.01% | ||
| 2 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 941 | 7,000 | 0.01% | ||
| 3 | JPMORGAN CHASE & CO | 1,400 | 11,000 | 0.02% | ||
| 4 | BlackRock Investment Management, LLC | 1,457 | 11,000 | 0.02% | ||
| 5 | BLACKROCK ADVISORS LLC | 2,978 | 23,000 | 0.05% | ||
| 6 | BANK OF AMERICA CORP /DE/ | 4,000 | 31,000 | 0.06% | ||
| 7 | MORGAN STANLEY | 4,460 | 35,000 | 0.07% | ||
| 8 | FNY Managed Accounts LLC | 5,000 | 39,100 | 0.08% | ||
| 9 | NORTHERN TRUST CORP | 12,846 | 100,000 | 0.21% | ||
| 10 | BlackRock Fund Advisors | 20,578 | 161,000 | 0.34% | ||
| 11 | GEODE CAPITAL MANAGEMENT, LLC | 52,976 | 415,000 | 0.87% | ||
| 12 | Weiss Multi-Strategy Advisers LLC | 65,000 | 508,000 | 1.06% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 100,003 | 782,000 | 1.63% | ||
| 14 | PURA VIDA INVESTMENTS, LLC | 114,067 | 892,000 | 1.86% | ||
| 15 | Knoll Capital Management, LLC | 135,800 | 1,038,000 | 2.17% | ||
| 16 | VANGUARD GROUP INC | 132,886 | 1,043,000 | 2.18% | ||
| 17 | BAKER BROS. ADVISORS LP | 142,000 | 1,110,000 | 2.32% | ||
| 18 | BOXER CAPITAL, LLC | 291,230 | 2,286,000 | 4.77% | ||
| 19 | SPHERA FUNDS MANAGEMENT LTD. | 368,500 | 2,893,000 | 6.04% | ||
| 20 | AWM Investment Company, Inc. | 917,810 | 7,205,000 | 15.05% | ||
| 21 | FMR LLC | 1,797,811 | 14,113,000 | 29.47% | ||
| 22 | PERCEPTIVE ADVISORS LLC | 1,940,458 | 15,174,000 | 31.69% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
