| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Capital Research Global Investors | 6,014,453 | 300,723,000 | 15.66% | ||
| 2 | JPMORGAN CHASE & CO | 3,168,056 | 158,402,000 | 8.25% | ||
| 3 | VANGUARD GROUP INC | 2,935,406 | 146,771,000 | 7.64% | ||
| 4 | VIKING GLOBAL INVESTORS LP | 2,525,497 | 126,275,000 | 6.58% | ||
| 5 | Wildcat Capital Management, LLC | 2,358,084 | 117,904,000 | 6.14% | ||
| 6 | FMR LLC | 2,315,928 | 115,796,000 | 6.03% | ||
| 7 | BlackRock Fund Advisors | 1,656,795 | 82,840,000 | 4.31% | ||
| 8 | Capital World Investors | 1,523,000 | 76,150,000 | 3.97% | ||
| 9 | STATE STREET CORP | 1,431,129 | 71,557,000 | 3.73% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,017,884 | 50,894,000 | 2.65% | ||
| 11 | BB BIOTECH AG | 750,000 | 37,500,000 | 1.95% | ||
| 12 | Capital International Investors | 724,700 | 36,235,000 | 1.89% | ||
| 13 | MENORA MIVTACHIM HOLDINGS LTD. | 684,899 | 34,245,000 | 1.78% | ||
| 14 | RS INVESTMENT MANAGEMENT CO LLC | 453,501 | 22,675,000 | 1.18% | ||
| 15 | CAPITAL GUARDIAN TRUST CO | 450,200 | 22,510,000 | 1.17% | ||
| 16 | NORTHERN TRUST CORP | 445,538 | 22,277,000 | 1.16% | ||
| 17 | FRANKLIN RESOURCES INC | 408,844 | 20,442,000 | 1.06% | ||
| 18 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 407,236 | 20,361,000 | 1.06% | ||
| 19 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 388,000 | 19,400,000 | 1.01% | Call | |
| 20 | J.P. Morgan Private Wealth Advisors LLC | 368,335 | 18,418,000 | 0.96% | ||
| 21 | Artal Group S.A. | 325,000 | 16,250,000 | 0.85% | ||
| 22 | NORGES BANK | 323,365 | 16,168,000 | 0.84% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 314,073 | 15,703,000 | 0.82% | ||
| 24 | PFM Health Sciences, LP | 311,765 | 15,588,000 | 0.81% | ||
| 25 | AMERICAN CENTURY COMPANIES INC | 300,160 | 15,008,000 | 0.78% | ||
| 26 | RTW INVESTMENTS, LP | 285,518 | 14,276,000 | 0.74% | ||
| 27 | LLBH PRIVATE WEALTH MANAGEMENT, LLC | 250,040 | 12,502,000 | 0.65% | ||
| 28 | PRICE T ROWE ASSOCIATES INC /MD/ | 239,742 | 11,987,000 | 0.62% | ||
| 29 | DSAM Partners (London) Ltd | 231,385 | 11,569,000 | 0.60% | ||
| 30 | FRONTIER CAPITAL MANAGEMENT CO LLC | 218,601 | 10,930,000 | 0.57% | ||
| 31 | Bank of New York Mellon Corp | 210,127 | 10,507,000 | 0.55% | ||
| 32 | MIGDAL INSURANCE & FINANCIAL HOLDINGS LTD. | 200,000 | 10,000,000 | 0.52% | ||
| 33 | CITADEL ADVISORS LLC | 189,953 | 9,498,000 | 0.49% | ||
| 34 | PICTET ASSET MANAGEMENT LTD | 183,643 | 9,412,000 | 0.49% | ||
| 35 | Candriam S.C.A. | 179,550 | 8,978,000 | 0.47% | ||
| 36 | TIAA CREF INVESTMENT MANAGEMENT LLC | 167,651 | 8,383,000 | 0.44% | ||
| 37 | ROYAL BANK OF CANADA | 167,206 | 8,360,000 | 0.44% | ||
| 38 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 165,000 | 8,250,000 | 0.43% | Put | |
| 39 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 151,428 | 7,572,000 | 0.39% | ||
| 40 | EVENTIDE ASSET MANAGEMENT, LLC | 148,600 | 7,430,000 | 0.39% | ||
| 41 | BlackRock Investment Management, LLC | 146,226 | 7,311,000 | 0.38% | ||
| 42 | DekaBank Deutsche Girozentrale | 142,950 | 7,289,000 | 0.38% | ||
| 43 | DEUTSCHE BANK AG\ | 136,093 | 6,803,000 | 0.35% | ||
| 44 | UBS Group AG | 129,171 | 6,458,000 | 0.34% | ||
| 45 | Zurcher Kantonalbank (Zurich Cantonalbank) | 105,614 | 5,281,000 | 0.28% | ||
| 46 | TEACHERS ADVISORS, LLC | 99,850 | 4,993,000 | 0.26% | ||
| 47 | MARSHALL WACE, LLP | 93,050 | 4,653,000 | 0.24% | ||
| 48 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 92,800 | 4,640,000 | 0.24% | ||
| 49 | GAM Holding AG | 86,800 | 4,340,000 | 0.23% | ||
| 50 | SOCIETE GENERALE | 84,746 | 4,237,000 | 0.22% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
