| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | NEA Management Company, LLC | 10,294,096 | 164,397,000 | 52.15% | ||
| 2 | FMR LLC | 2,597,944 | 41,489,000 | 13.16% | ||
| 3 | RA CAPITAL MANAGEMENT, L.P. | 1,719,945 | 27,468,000 | 8.71% | ||
| 4 | Cormorant Asset Management, LP | 1,481,075 | 23,653,000 | 7.50% | ||
| 5 | Rock Springs Capital Management LP | 610,000 | 9,742,000 | 3.09% | ||
| 6 | Broadfin Capital, LLC | 649,290 | 8,877,000 | 2.82% | ||
| 7 | WALL STREET ASSOCIATES | 380,400 | 6,075,000 | 1.93% | ||
| 8 | BlackRock Fund Advisors | 314,384 | 5,021,000 | 1.59% | ||
| 9 | VANGUARD GROUP INC | 178,658 | 2,853,000 | 0.91% | ||
| 10 | MILLENNIUM MANAGEMENT LLC | 167,408 | 2,674,000 | 0.85% | ||
| 11 | Finepoint Capital LP | 136,866 | 2,186,000 | 0.69% | ||
| 12 | PUTNAM INVESTMENTS LLC | 104,300 | 1,666,000 | 0.53% | ||
| 13 | JPMORGAN CHASE & CO | 95,575 | 1,526,000 | 0.48% | ||
| 14 | MORGAN STANLEY | 91,578 | 1,463,000 | 0.46% | ||
| 15 | PRINCIPAL FINANCIAL GROUP INC | 88,291 | 1,410,000 | 0.45% | ||
| 16 | FIRST MANHATTAN CO. LLC. | 86,031 | 1,373,000 | 0.44% | ||
| 17 | BLACKROCK ADVISORS LLC | 80,796 | 1,290,000 | 0.41% | ||
| 18 | BlackRock Institutional Trust Company, N.A. | 79,218 | 1,265,000 | 0.40% | ||
| 19 | NORTHERN TRUST CORP | 65,332 | 1,043,000 | 0.33% | ||
| 20 | PANAGORA ASSET MANAGEMENT INC | 60,506 | 966,000 | 0.31% | ||
| 21 | GSA CAPITAL PARTNERS LLP | 52,472 | 838,000 | 0.27% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 51,489 | 822,000 | 0.26% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 42,636 | 680,000 | 0.22% | ||
| 24 | BlackRock Investment Management, LLC | 42,527 | 679,000 | 0.22% | ||
| 25 | Bank of New York Mellon Corp | 37,076 | 592,000 | 0.19% | ||
| 26 | DEUTSCHE BANK AG\ | 32,875 | 524,000 | 0.17% | ||
| 27 | HARBOURVEST PARTNERS LLC | 32,584 | 520,000 | 0.16% | ||
| 28 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 30,000 | 479,000 | 0.15% | ||
| 29 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 21,854 | 349,000 | 0.11% | ||
| 30 | BANK OF MONTREAL /CAN/ | 24,349 | 323,000 | 0.10% | ||
| 31 | ALPS ADVISORS INC | 18,461 | 295,000 | 0.09% | ||
| 32 | TEACHERS ADVISORS, LLC | 17,444 | 279,000 | 0.09% | ||
| 33 | CITIGROUP INC | 17,192 | 274,000 | 0.09% | ||
| 34 | BlackRock Group LTD | 16,855 | 269,000 | 0.09% | ||
| 35 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 16,840 | 269,000 | 0.09% | ||
| 36 | ClariVest Asset Management LLC | 15,100 | 241,000 | 0.08% | ||
| 37 | SABBY MANAGEMENT, LLC | 13,757 | 220,000 | 0.07% | ||
| 38 | RENAISSANCE TECHNOLOGIES LLC | 12,600 | 201,000 | 0.06% | ||
| 39 | STRS OHIO | 10,000 | 159,000 | 0.05% | ||
| 40 | NEW YORK STATE COMMON RETIREMENT FUND | 9,705 | 155,000 | 0.05% | ||
| 41 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 8,444 | 135,000 | 0.04% | ||
| 42 | Nationwide Fund Advisors | 7,733 | 123,000 | 0.04% | ||
| 43 | AMERICAN INTERNATIONAL GROUP, INC. | 7,013 | 111,998 | 0.04% | ||
| 44 | BESSEMER GROUP INC | 5,119 | 82,000 | 0.03% | ||
| 45 | GLENMEDE TRUST CO NA | 3,960 | 63,000 | 0.02% | ||
| 46 | BANK OF AMERICA CORP /DE/ | 1,283 | 20,000 | 0.01% | ||
| 47 | BlackRock Japan Co. Ltd | 1,104 | 18,000 | 0.01% | ||
| 48 | PRELUDE CAPITAL MANAGEMENT, LLC | 1,000 | 16,000 | 0.01% | ||
| 49 | BNP PARIBAS FINANCIAL MARKETS | 996 | 15,906 | 0.01% | ||
| 50 | ROYAL BANK OF CANADA | 804 | 13,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
