| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Lombard Odier Asset Management (USA) Corp | 1,311,000 | 9,072,000 | 15.99% | ||
| 2 | Versant Venture Management, LLC | 1,048,601 | 7,256,319 | 12.79% | ||
| 3 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 1,000,000 | 6,920,000 | 12.19% | ||
| 4 | JENNISON ASSOCIATES LLC | 921,155 | 6,374,000 | 11.23% | ||
| 5 | EverPoint Asset Management, LLC | 800,000 | 5,536,000 | 9.76% | ||
| 6 | Visium Asset Management, LP | 753,791 | 5,216,000 | 9.19% | ||
| 7 | Point72 Asset Management, L.P. | 585,288 | 4,050,000 | 7.14% | ||
| 8 | Iguana Healthcare Management, LLC | 500,000 | 3,460,000 | 6.10% | ||
| 9 | VANGUARD GROUP INC | 318,047 | 2,201,000 | 3.88% | ||
| 10 | ALLIANCEBERNSTEIN L.P. | 234,974 | 1,626,000 | 2.87% | ||
| 11 | SPHERA FUNDS MANAGEMENT LTD. | 157,179 | 1,088,000 | 1.92% | ||
| 12 | SABBY MANAGEMENT, LLC | 100,000 | 692,000 | 1.22% | ||
| 13 | MORGAN STANLEY | 88,171 | 610,000 | 1.07% | ||
| 14 | Spark Investment Management LLC | 60,300 | 417,000 | 0.73% | ||
| 15 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 54,108 | 374,000 | 0.66% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 49,022 | 339,000 | 0.60% | ||
| 17 | ACADIAN ASSET MANAGEMENT LLC | 30,383 | 211,000 | 0.37% | ||
| 18 | CITADEL ADVISORS LLC | 26,373 | 183,000 | 0.32% | ||
| 19 | Jefferies Group LLC | 21,646 | 150,000 | 0.26% | ||
| 20 | BNP PARIBAS FINANCIAL MARKETS | 20,000 | 138,400 | 0.24% | ||
| 21 | Geduld E E | 20,000 | 138,000 | 0.24% | ||
| 22 | Alpha Cubed Investments, LLC | 20,000 | 138,000 | 0.24% | ||
| 23 | MENTA CAPITAL LLC | 18,356 | 127,000 | 0.22% | ||
| 24 | NORTHERN TRUST CORP | 18,024 | 125,000 | 0.22% | ||
| 25 | EAGLE GLOBAL ADVISORS LLC | 16,630 | 115,000 | 0.20% | ||
| 26 | A.R.T. Advisors, LLC | 15,129 | 104,000 | 0.18% | ||
| 27 | PDT Partners, LLC | 12,500 | 87,000 | 0.15% | ||
| 28 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 257 | 2,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
