| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VANGUARD GROUP INC | 12,242,679 | 198,088,000 | 7.92% | ||
| 2 | DEERFIELD MANAGEMENT COMPANY, L.P. | 8,956,988 | 144,924,000 | 5.80% | ||
| 3 | SCOPIA CAPITAL MANAGEMENT LP | 8,081,650 | 130,761,000 | 5.23% | ||
| 4 | BlackRock Fund Advisors | 7,891,641 | 127,687,000 | 5.11% | ||
| 5 | JPMORGAN CHASE & CO | 6,804,117 | 110,090,000 | 4.40% | ||
| 6 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 6,682,618 | 108,125,000 | 4.32% | ||
| 7 | Broadfin Capital, LLC | 5,959,819 | 96,430,000 | 3.86% | ||
| 8 | Consonance Capital Management LP | 5,793,903 | 93,745,000 | 3.75% | ||
| 9 | FMR LLC | 5,702,959 | 92,274,000 | 3.69% | ||
| 10 | KINGDON CAPITAL MANAGEMENT, L.L.C. | 4,503,900 | 72,873,000 | 2.91% | Call | |
| 11 | STATE STREET CORP | 4,339,978 | 70,222,000 | 2.81% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 4,181,628 | 67,659,000 | 2.71% | ||
| 13 | JANUS HENDERSON INVESTORS US LLC | 3,692,074 | 59,746,000 | 2.39% | ||
| 14 | ALLIANCEBERNSTEIN L.P. | 3,539,509 | 57,269,000 | 2.29% | ||
| 15 | BARCLAYS PLC | 3,093,700 | 50,056,000 | 2.00% | Call | |
| 16 | DIMENSIONAL FUND ADVISORS LP | 2,591,605 | 41,933,000 | 1.68% | ||
| 17 | Brandywine Global Investment Management, LLC | 2,491,773 | 40,317,000 | 1.61% | ||
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,367,500 | 38,306,000 | 1.53% | Call | |
| 19 | NORGES BANK | 1,944,782 | 31,467,000 | 1.26% | ||
| 20 | NORTHERN TRUST CORP | 1,941,669 | 31,416,000 | 1.26% | ||
| 21 | CAPITAL GROWTH MANAGEMENT LP | 1,530,000 | 24,755,000 | 0.99% | ||
| 22 | BARCLAYS PLC | 1,453,700 | 23,521,000 | 0.94% | Put | |
| 23 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,436,900 | 23,249,000 | 0.93% | Put | |
| 24 | Fiera Capital Corp | 1,419,801 | 22,973,000 | 0.92% | ||
| 25 | GEODE CAPITAL MANAGEMENT, LLC | 1,370,105 | 22,167,000 | 0.89% | ||
| 26 | FRANKLIN RESOURCES INC | 1,310,990 | 21,211,000 | 0.85% | ||
| 27 | EverPoint Asset Management, LLC | 1,300,000 | 21,034,000 | 0.84% | ||
| 28 | ROTHSCHILD & CO ASSET MANAGEMENT US INC. | 1,200,503 | 19,424,000 | 0.78% | ||
| 29 | LION POINT CAPITAL, LP | 1,164,414 | 18,840,000 | 0.75% | ||
| 30 | GLENMEDE TRUST CO NA | 1,140,538 | 18,452,000 | 0.74% | ||
| 31 | D. E. Shaw & Co., Inc. | 1,123,939 | 18,185,000 | 0.73% | ||
| 32 | NEXT CENTURY GROWTH INVESTORS LLC | 1,112,751 | 18,004,000 | 0.72% | ||
| 33 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 1,106,263 | 17,900,000 | 0.72% | ||
| 34 | KENNEDY CAPITAL MANAGEMENT LLC | 1,090,041 | 17,637,000 | 0.71% | ||
| 35 | GOLDMAN SACHS GROUP INC | 983,271 | 15,909,000 | 0.64% | ||
| 36 | VOYA INVESTMENT MANAGEMENT LLC | 946,764 | 15,319,000 | 0.61% | ||
| 37 | TEACHERS ADVISORS, LLC | 892,711 | 14,444,000 | 0.58% | ||
| 38 | MORGAN STANLEY | 890,784 | 14,413,000 | 0.58% | ||
| 39 | UBS Group AG | 824,154 | 13,334,000 | 0.53% | ||
| 40 | Broadfin Capital, LLC | 800,000 | 12,944,000 | 0.52% | Call | |
| 41 | TIGER MANAGEMENT L.L.C. | 793,933 | 12,846,000 | 0.51% | ||
| 42 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 771,212 | 12,478,000 | 0.50% | ||
| 43 | Bank of New York Mellon Corp | 741,653 | 12,001,000 | 0.48% | ||
| 44 | Rhenman & Partners Asset Management AB | 700,000 | 11,326,000 | 0.45% | ||
| 45 | ROYAL BANK OF CANADA | 657,331 | 10,635,000 | 0.43% | ||
| 46 | ARMISTICE CAPITAL, LLC | 650,000 | 10,517,000 | 0.42% | ||
| 47 | FARALLON CAPITAL MANAGEMENT LLC | 610,000 | 9,870,000 | 0.39% | ||
| 48 | BlackRock Investment Management, LLC | 603,431 | 9,764,000 | 0.39% | ||
| 49 | HIGHBRIDGE CAPITAL MANAGEMENT LLC | 577,242 | 9,340,000 | 0.37% | ||
| 50 | Point72 Asset Management, L.P. | 572,900 | 9,270,000 | 0.37% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
