| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 26,514,461 | 219,275,000 | 14.93% | ||
| 2 | PRICE T ROWE ASSOCIATES INC /MD/ | 19,867,541 | 164,305,000 | 11.19% | ||
| 3 | FIRST TRUST ADVISORS LP | 14,118,033 | 116,756,000 | 7.95% | ||
| 4 | VANGUARD GROUP INC | 12,392,843 | 102,489,000 | 6.98% | ||
| 5 | BlackRock Fund Advisors | 9,117,614 | 75,403,000 | 5.13% | ||
| 6 | BB BIOTECH AG | 8,450,000 | 69,882,000 | 4.76% | ||
| 7 | Invesco Ltd. | 7,381,106 | 61,042,000 | 4.16% | ||
| 8 | WELLINGTON MANAGEMENT GROUP LLP | 6,719,149 | 55,567,000 | 3.78% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 6,489,822 | 53,671,000 | 3.65% | ||
| 10 | WELLS FARGO & COMPANY/MN | 6,411,440 | 53,023,000 | 3.61% | ||
| 11 | STATE STREET CORP | 6,189,888 | 51,194,000 | 3.49% | ||
| 12 | FRANKLIN RESOURCES INC | 3,352,865 | 27,728,000 | 1.89% | ||
| 13 | NORTHERN TRUST CORP | 2,812,210 | 23,257,000 | 1.58% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,418,967 | 20,005,000 | 1.36% | ||
| 15 | BNP Paribas Asset Management Holding S.A. | 2,064,801 | 17,076,000 | 1.16% | ||
| 16 | NORGES BANK | 1,998,096 | 16,524,000 | 1.13% | ||
| 17 | BAKER BROS. ADVISORS LP | 1,945,687 | 16,091,000 | 1.10% | ||
| 18 | EVENTIDE ASSET MANAGEMENT, LLC | 1,908,700 | 15,785,000 | 1.07% | ||
| 19 | MORGAN STANLEY | 1,560,530 | 12,905,000 | 0.88% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 1,506,331 | 12,457,000 | 0.85% | ||
| 21 | RA CAPITAL MANAGEMENT, L.P. | 1,431,232 | 11,836,000 | 0.81% | ||
| 22 | CITY NATIONAL BANK | 1,405,034 | 11,619,000 | 0.79% | ||
| 23 | Bank of New York Mellon Corp | 1,402,019 | 11,595,000 | 0.79% | ||
| 24 | NORTHPOINTE CAPITAL LLC | 1,311,944 | 10,850,000 | 0.74% | ||
| 25 | Cormorant Asset Management, LP | 1,238,300 | 10,241,000 | 0.70% | ||
| 26 | AMERIPRISE FINANCIAL INC | 1,000,180 | 8,272,000 | 0.56% | ||
| 27 | MASSACHUSETTS FINANCIAL SERVICES CO /MA/ | 977,298 | 8,082,254 | 0.55% | ||
| 28 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 860,100 | 7,113,000 | 0.48% | Put | |
| 29 | MCKINLEY CAPITAL MANAGEMENT LLC | 840,641 | 6,952,000 | 0.47% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 805,728 | 6,663,000 | 0.45% | ||
| 31 | DEUTSCHE BANK AG\ | 796,804 | 6,588,000 | 0.45% | ||
| 32 | GUGGENHEIM CAPITAL LLC | 781,420 | 6,462,000 | 0.44% | ||
| 33 | WILLIAM HARRIS INVESTORS INC | 768,702 | 6,357,000 | 0.43% | ||
| 34 | Rock Springs Capital Management LP | 730,000 | 6,037,000 | 0.41% | ||
| 35 | STONERIDGE INVESTMENT PARTNERS LLC | 725,166 | 5,997,000 | 0.41% | ||
| 36 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 717,458 | 5,934,000 | 0.40% | ||
| 37 | Nationwide Fund Advisors | 703,432 | 5,817,000 | 0.40% | ||
| 38 | BlackRock Investment Management, LLC | 657,438 | 5,437,000 | 0.37% | ||
| 39 | NEW YORK STATE COMMON RETIREMENT FUND | 647,635 | 5,356,000 | 0.36% | ||
| 40 | PANAGORA ASSET MANAGEMENT INC | 624,290 | 5,163,000 | 0.35% | ||
| 41 | HARVEY CAPITAL MANAGEMENT INC | 616,950 | 5,102,000 | 0.35% | ||
| 42 | D. E. Shaw & Co., Inc. | 562,332 | 4,650,000 | 0.32% | ||
| 43 | TD ASSET MANAGEMENT INC | 552,500 | 4,569,000 | 0.31% | ||
| 44 | Informed Momentum Co LLC | 543,283 | 4,493,000 | 0.31% | ||
| 45 | BELLEVUE ASSET MANAGEMENT AG | 520,000 | 4,300,000 | 0.29% | ||
| 46 | PRUDENTIAL FINANCIAL INC | 468,353 | 3,873,000 | 0.26% | ||
| 47 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 435,437 | 3,601,000 | 0.25% | ||
| 48 | ALLIANCEBERNSTEIN L.P. | 399,961 | 3,308,000 | 0.23% | ||
| 49 | AWM Investment Company, Inc. | 400,000 | 3,308,000 | 0.23% | ||
| 50 | EverPoint Asset Management, LLC | 400,000 | 3,308,000 | 0.23% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
