| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 6,090,829 | 6,395,000 | 15.28% | ||
| 2 | MORGAN STANLEY | 5,258,293 | 5,520,000 | 13.19% | ||
| 3 | Avoro Capital Advisors LLC | 3,889,900 | 4,084,000 | 9.76% | ||
| 4 | STONEPINE CAPITAL MANAGEMENT, LLC | 3,215,861 | 3,377,000 | 8.07% | ||
| 5 | Point72 Asset Management, L.P. | 2,500,000 | 2,625,000 | 6.27% | ||
| 6 | Elk Creek Partners, LLC | 2,308,946 | 2,424,000 | 5.79% | ||
| 7 | Aisling Capital LLC | 2,010,000 | 2,111,000 | 5.04% | ||
| 8 | VANGUARD GROUP INC | 1,796,619 | 1,887,000 | 4.51% | ||
| 9 | BlackRock Institutional Trust Company, N.A. | 1,516,585 | 1,592,000 | 3.80% | ||
| 10 | BlackRock Fund Advisors | 1,117,822 | 1,174,000 | 2.80% | ||
| 11 | ORBIMED ADVISORS LLC | 1,073,000 | 1,127,000 | 2.69% | ||
| 12 | AQR CAPITAL MANAGEMENT LLC | 1,013,108 | 1,064,000 | 2.54% | ||
| 13 | JUPITER ASSET MANAGEMENT LTD | 1,008,650 | 1,059,000 | 2.53% | ||
| 14 | STATE STREET CORP | 594,274 | 625,000 | 1.49% | ||
| 15 | ARMISTICE CAPITAL, LLC | 582,000 | 611,000 | 1.46% | ||
| 16 | ACADIAN ASSET MANAGEMENT LLC | 567,542 | 595,000 | 1.42% | ||
| 17 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 517,456 | 543,000 | 1.30% | ||
| 18 | NORTHERN TRUST CORP | 478,323 | 502,000 | 1.20% | ||
| 19 | WALL STREET ASSOCIATES | 274,600 | 288,000 | 0.69% | ||
| 20 | PANAGORA ASSET MANAGEMENT INC | 266,900 | 280,000 | 0.67% | ||
| 21 | GEODE CAPITAL MANAGEMENT, LLC | 253,122 | 265,000 | 0.63% | ||
| 22 | BLACKROCK ADVISORS LLC | 248,675 | 261,000 | 0.62% | ||
| 23 | DIMENSIONAL FUND ADVISORS LP | 229,792 | 241,000 | 0.58% | ||
| 24 | MENTA CAPITAL LLC | 195,136 | 205,000 | 0.49% | ||
| 25 | GLOBEFLEX CAPITAL L P | 192,267 | 202,000 | 0.48% | ||
| 26 | D. E. Shaw & Co., Inc. | 173,109 | 182,000 | 0.43% | ||
| 27 | SEARLE & CO. | 172,500 | 179,000 | 0.43% | ||
| 28 | BlackRock Investment Management, LLC | 160,880 | 169,000 | 0.40% | ||
| 29 | Connor, Clark & Lunn Investment Management Ltd. | 157,100 | 165,000 | 0.39% | ||
| 30 | TIAA CREF INVESTMENT MANAGEMENT LLC | 144,601 | 152,000 | 0.36% | ||
| 31 | Bank of New York Mellon Corp | 141,172 | 148,000 | 0.35% | ||
| 32 | EAGLE GLOBAL ADVISORS LLC | 141,260 | 148,000 | 0.35% | ||
| 33 | RENAISSANCE TECHNOLOGIES LLC | 131,937 | 139,000 | 0.33% | ||
| 34 | GOLDMAN SACHS GROUP INC | 128,398 | 135,000 | 0.32% | ||
| 35 | MILLENNIUM MANAGEMENT LLC | 120,511 | 127,000 | 0.30% | ||
| 36 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 94,167 | 99,000 | 0.24% | ||
| 37 | BANK OF AMERICA CORP /DE/ | 92,009 | 97,000 | 0.23% | ||
| 38 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 78,456 | 82,000 | 0.20% | ||
| 39 | TEACHERS ADVISORS, LLC | 67,466 | 71,000 | 0.17% | ||
| 40 | DEUTSCHE BANK AG\ | 68,884 | 71,000 | 0.17% | ||
| 41 | JACOBS LEVY EQUITY MANAGEMENT, INC | 55,150 | 58,000 | 0.14% | ||
| 42 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 48,800 | 52,000 | 0.12% | ||
| 43 | RHUMBLINE ADVISERS | 45,358 | 48,000 | 0.11% | ||
| 44 | BlackRock Group LTD | 42,239 | 44,000 | 0.11% | ||
| 45 | NEW YORK STATE COMMON RETIREMENT FUND | 39,600 | 42,000 | 0.10% | ||
| 46 | ALLIANCEBERNSTEIN L.P. | 40,018 | 42,000 | 0.10% | ||
| 47 | CITIGROUP INC | 36,718 | 38,000 | 0.09% | ||
| 48 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 30,881 | 33,000 | 0.08% | ||
| 49 | TFS CAPITAL LLC | 30,607 | 32,000 | 0.08% | ||
| 50 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 29,377 | 31,000 | 0.07% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
