| 1 |
RENAISSANCE TECHNOLOGIES LLC |
4,843,189 |
3,013,000 |
37.34% |
|
|
| 2 |
Aisling Capital LLC |
2,010,000 |
1,246,000 |
15.44% |
|
|
| 3 |
BlackRock Institutional Trust Company, N.A. |
1,610,542 |
1,002,000 |
12.42% |
|
|
| 4 |
ORBIMED ADVISORS LLC |
1,073,000 |
668,000 |
8.28% |
|
|
| 5 |
VANGUARD GROUP INC |
941,155 |
585,000 |
7.25% |
|
|
| 6 |
GEODE CAPITAL MANAGEMENT, LLC |
372,734 |
231,000 |
2.86% |
|
|
| 7 |
GOLDMAN SACHS GROUP INC |
325,573 |
203,000 |
2.52% |
|
|
| 8 |
GSA CAPITAL PARTNERS LLP |
247,500 |
154,000 |
1.91% |
|
|
| 9 |
Jefferies Group LLC |
200,000 |
124,000 |
1.54% |
|
|
| 10 |
SEARLE & CO. |
172,500 |
105,000 |
1.30% |
|
|
| 11 |
BlackRock Fund Advisors |
135,144 |
84,000 |
1.04% |
|
|
| 12 |
CITADEL ADVISORS LLC |
126,980 |
79,000 |
0.98% |
|
|
| 13 |
MILLENNIUM MANAGEMENT LLC |
120,875 |
75,000 |
0.93% |
|
|
| 14 |
BANK OF AMERICA CORP /DE/ |
113,208 |
70,000 |
0.87% |
|
|
| 15 |
ROYAL BANK OF CANADA |
101,030 |
63,000 |
0.78% |
|
|
| 16 |
ACUTA CAPITAL PARTNERS, LLC |
73,500 |
46,000 |
0.57% |
Put |
|
| 17 |
NORTHERN TRUST CORP |
57,209 |
36,000 |
0.45% |
|
|
| 18 |
HIGHLAND CAPITAL MANAGEMENT, LLC |
41,000 |
26,000 |
0.32% |
|
|
| 19 |
Bank of New York Mellon Corp |
38,332 |
24,000 |
0.30% |
|
|
| 20 |
MORGAN STANLEY |
34,695 |
22,000 |
0.27% |
|
|
| 21 |
STOCK YARDS BANK & TRUST CO |
30,170 |
19,000 |
0.24% |
|
|
| 22 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
29,000 |
18,000 |
0.22% |
|
|
| 23 |
UBS Group AG |
27,743 |
17,000 |
0.21% |
|
|
| 24 |
Cambridge Investment Research Advisors, Inc. |
28,000 |
17,000 |
0.21% |
|
|
| 25 |
GUGGENHEIM CAPITAL LLC |
26,429 |
16,000 |
0.20% |
|
|
| 26 |
GOODWIN DANIEL L |
22,679 |
14,000 |
0.17% |
|
|
| 27 |
STATE STREET CORP |
21,619 |
14,000 |
0.17% |
|
|
| 28 |
CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM |
20,800 |
13,000 |
0.16% |
|
|
| 29 |
SUSQUEHANNA INTERNATIONAL GROUP, LLP |
20,175 |
13,000 |
0.16% |
|
|
| 30 |
ADVISOR GROUP, INC. |
19,761 |
12,000 |
0.15% |
|
|
| 31 |
Virtu KCG Holdings LLC |
19,936 |
12,000 |
0.15% |
|
|
| 32 |
OPPENHEIMER & CO INC |
13,500 |
8,000 |
0.10% |
|
|
| 33 |
COMMERZBANK AKTIENGESELLSCHAFT /FI |
11,500 |
7,000 |
0.09% |
|
|
| 34 |
BOSTON FINANCIAL MANGEMENT LLC |
11,000 |
7,000 |
0.09% |
|
|
| 35 |
SANDERS MORRIS HARRIS INC/FA |
10,000 |
6,000 |
0.07% |
|
|
| 36 |
SHANDA ASSET MANAGEMENT HOLDINGS Ltd |
10,000 |
6,000 |
0.07% |
|
|
| 37 |
BLACKROCK ADVISORS LLC |
7,631 |
5,000 |
0.06% |
|
|
| 38 |
WELLS FARGO & COMPANY/MN |
4,751 |
3,000 |
0.04% |
|
|
| 39 |
SIMPLEX TRADING, LLC |
3,419 |
2,000 |
0.02% |
|
|
| 40 |
CUTLER GROUP LLC / CA |
3,532 |
2,000 |
0.02% |
|
|
| 41 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
1,037 |
1,000 |
0.01% |
|
|
| 42 |
TCI Wealth Advisors, Inc. |
2,000 |
1,000 |
0.01% |
|
PRN |
| 43 |
BARCLAYS PLC |
576 |
0 |
0.00% |
|
|
| 44 |
Avior Wealth Management, LLC |
700 |
0 |
0.00% |
|
|
| 45 |
LADENBURG THALMANN FINANCIAL SERVICES INC. |
50 |
0 |
0.00% |
|
|
| 46 |
DEUTSCHE BANK AG\ |
1 |
0 |
0.00% |
|
|
| 47 |
MSI Financial Services Inc |
123 |
0 |
0.00% |
|
|
