| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 5,367,300 | 91,244,000 | 51.29% | ||
| 2 | BVF INC/IL | 1,441,287 | 24,502,000 | 13.77% | ||
| 3 | Assured Investment Management LLC | 1,344,495 | 22,856,000 | 12.85% | ||
| 4 | ORBIMED ADVISORS LLC | 798,000 | 13,566,000 | 7.63% | ||
| 5 | Cormorant Asset Management, LP | 335,068 | 5,696,000 | 3.20% | ||
| 6 | Sio Capital Management, LLC | 216,405 | 3,679,000 | 2.07% | ||
| 7 | PERCEPTIVE ADVISORS LLC | 186,300 | 3,167,000 | 1.78% | ||
| 8 | Tekla Capital Management LLC | 136,547 | 2,321,000 | 1.30% | ||
| 9 | SPHERA FUNDS MANAGEMENT LTD. | 121,500 | 2,066,000 | 1.16% | ||
| 10 | EcoR1 Capital, LLC | 97,024 | 1,649,000 | 0.93% | ||
| 11 | SABBY MANAGEMENT, LLC | 76,785 | 1,305,000 | 0.73% | ||
| 12 | Gruss Capital Management LP | 75,000 | 1,275,000 | 0.72% | ||
| 13 | EverPoint Asset Management, LLC | 64,608 | 1,098,000 | 0.62% | ||
| 14 | Motley Fool Wealth Management, LLC | 64,231 | 1,092,000 | 0.61% | ||
| 15 | ALPS ADVISORS INC | 52,310 | 889,000 | 0.50% | ||
| 16 | Iguana Healthcare Management, LLC | 30,000 | 510,000 | 0.29% | ||
| 17 | D. E. Shaw & Co., Inc. | 17,371 | 295,000 | 0.17% | ||
| 18 | DRW Securities, LLC | 17,252 | 293,000 | 0.16% | ||
| 19 | Point72 Asset Management, L.P. | 13,100 | 223,000 | 0.13% | ||
| 20 | MORGAN STANLEY | 5,498 | 93,000 | 0.05% | ||
| 21 | ROYAL BANK OF CANADA | 1,950 | 33,000 | 0.02% | ||
| 22 | ACROSPIRE INVESTMENT MANAGEMENT LLC | 1,222 | 21,000 | 0.01% | ||
| 23 | BESSEMER GROUP INC | 1,085 | 18,000 | 0.01% | ||
| 24 | INTEGRATED WEALTH MANAGEMENT | 500 | 9,000 | 0.01% | ||
| 25 | DEUTSCHE BANK AG\ | 312 | 5,000 | 0.00% | ||
| 26 | Tower Research Capital LLC (TRC) | 297 | 5,000 | 0.00% | ||
| 27 | UBS Group AG | 200 | 3,000 | 0.00% | ||
| 28 | Creative Planning | 50 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
