| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 5,367,300 | 97,524,000 | 51.84% | ||
| 2 | BVF INC/IL | 1,424,611 | 25,885,000 | 13.76% | ||
| 3 | Assured Investment Management LLC | 1,344,495 | 24,429,000 | 12.99% | ||
| 4 | ORBIMED ADVISORS LLC | 798,000 | 14,500,000 | 7.71% | ||
| 5 | Cormorant Asset Management, LP | 339,175 | 6,163,000 | 3.28% | ||
| 6 | PERCEPTIVE ADVISORS LLC | 311,400 | 5,658,000 | 3.01% | ||
| 7 | Tekla Capital Management LLC | 136,547 | 2,481,000 | 1.32% | ||
| 8 | Sio Capital Management, LLC | 124,475 | 2,262,000 | 1.20% | ||
| 9 | SPHERA FUNDS MANAGEMENT LTD. | 121,500 | 2,208,000 | 1.17% | ||
| 10 | SABBY MANAGEMENT, LLC | 102,135 | 1,856,000 | 0.99% | ||
| 11 | EcoR1 Capital, LLC | 84,332 | 1,532,000 | 0.81% | ||
| 12 | Gruss Capital Management LP | 75,000 | 1,363,000 | 0.72% | ||
| 13 | Motley Fool Wealth Management, LLC | 68,760 | 1,249,000 | 0.66% | ||
| 14 | DRW Securities, LLC | 17,252 | 313,000 | 0.17% | ||
| 15 | D. E. Shaw & Co., Inc. | 16,868 | 306,000 | 0.16% | ||
| 16 | GOLDMAN SACHS GROUP INC | 10,275 | 187,000 | 0.10% | ||
| 17 | MORGAN STANLEY | 4,958 | 90,000 | 0.05% | ||
| 18 | ROYAL BANK OF CANADA | 1,800 | 33,000 | 0.02% | ||
| 19 | DEUTSCHE BANK AG\ | 1,542 | 28,000 | 0.01% | ||
| 20 | ACROSPIRE INVESTMENT MANAGEMENT LLC | 922 | 17,000 | 0.01% | ||
| 21 | ADVISOR GROUP, INC. | 927 | 16,000 | 0.01% | ||
| 22 | INTEGRATED WEALTH MANAGEMENT | 500 | 9,000 | 0.00% | ||
| 23 | UBS Group AG | 365 | 7,000 | 0.00% | ||
| 24 | Creative Planning | 50 | 1,000 | 0.00% | ||
| 25 | WOLVERINE TRADING LP /BD | 6 | 110 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
