| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 5,367,300 | 112,660,000 | 52.19% | ||
| 2 | BVF INC/IL | 1,387,853 | 29,145,000 | 13.50% | ||
| 3 | Assured Investment Management LLC | 1,344,495 | 28,234,000 | 13.08% | ||
| 4 | ORBIMED ADVISORS LLC | 798,000 | 16,750,000 | 7.76% | ||
| 5 | PERCEPTIVE ADVISORS LLC | 404,472 | 8,494,000 | 3.94% | ||
| 6 | Cormorant Asset Management, LP | 339,175 | 7,123,000 | 3.30% | ||
| 7 | Tekla Capital Management LLC | 136,547 | 2,867,000 | 1.33% | ||
| 8 | SPHERA FUNDS MANAGEMENT LTD. | 121,500 | 2,552,000 | 1.18% | ||
| 9 | SABBY MANAGEMENT, LLC | 99,053 | 2,080,000 | 0.96% | ||
| 10 | Sio Capital Management, LLC | 85,108 | 1,786,000 | 0.83% | ||
| 11 | Gruss Capital Management LP | 78,300 | 1,644,000 | 0.76% | ||
| 12 | Motley Fool Wealth Management, LLC | 69,495 | 1,459,000 | 0.68% | ||
| 13 | DRW Securities, LLC | 17,500 | 367,000 | 0.17% | ||
| 14 | D. E. Shaw & Co., Inc. | 15,218 | 320,000 | 0.15% | ||
| 15 | MORGAN STANLEY | 11,078 | 233,000 | 0.11% | ||
| 16 | BlackRock Institutional Trust Company, N.A. | 2,066 | 43,000 | 0.02% | ||
| 17 | ROYAL BANK OF CANADA | 1,800 | 38,000 | 0.02% | ||
| 18 | ADVISOR GROUP, INC. | 1,329 | 28,000 | 0.01% | ||
| 19 | ACROSPIRE INVESTMENT MANAGEMENT LLC | 522 | 11,000 | 0.01% | ||
| 20 | INTEGRATED WEALTH MANAGEMENT | 500 | 10,000 | 0.00% | ||
| 21 | UBS Group AG | 200 | 4,000 | 0.00% | ||
| 22 | US BANCORP \DE\ | 79 | 2,000 | 0.00% | ||
| 23 | Creative Planning | 50 | 1,000 | 0.00% | ||
| 24 | BANK OF AMERICA CORP /DE/ | 35 | 1,000 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
