| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 5,367,300 | 80,510,000 | 51.64% | ||
| 2 | BVF INC/IL | 1,387,853 | 20,832,000 | 13.36% | ||
| 3 | Assured Investment Management LLC | 1,335,719 | 20,049,000 | 12.86% | ||
| 4 | ORBIMED ADVISORS LLC | 798,000 | 11,970,000 | 7.68% | ||
| 5 | PERCEPTIVE ADVISORS LLC | 394,241 | 5,918,000 | 3.80% | ||
| 6 | Cormorant Asset Management, LP | 339,175 | 5,091,000 | 3.27% | ||
| 7 | Tekla Capital Management LLC | 136,547 | 2,050,000 | 1.31% | ||
| 8 | Gruss Capital Management LP | 128,300 | 1,925,000 | 1.23% | ||
| 9 | SPHERA FUNDS MANAGEMENT LTD. | 121,500 | 1,824,000 | 1.17% | ||
| 10 | SANDIA HOLDINGS, LLC | 110,058 | 1,651,000 | 1.06% | ||
| 11 | SABBY MANAGEMENT, LLC | 104,273 | 1,565,000 | 1.00% | ||
| 12 | Motley Fool Wealth Management, LLC | 72,339 | 1,085,000 | 0.70% | ||
| 13 | Sio Capital Management, LLC | 51,246 | 769,000 | 0.49% | ||
| 14 | MORGAN STANLEY | 21,147 | 318,000 | 0.20% | ||
| 15 | DRW Securities, LLC | 19,000 | 285,000 | 0.18% | ||
| 16 | ACROSPIRE INVESTMENT MANAGEMENT LLC | 1,600 | 24,000 | 0.02% | ||
| 17 | ADVISOR GROUP, INC. | 1,226 | 18,000 | 0.01% | ||
| 18 | ROYAL BANK OF CANADA | 1,104 | 17,000 | 0.01% | ||
| 19 | ENVESTNET ASSET MANAGEMENT INC | 360 | 5,000 | 0.00% | ||
| 20 | UBS Group AG | 200 | 3,000 | 0.00% | ||
| 21 | Creative Planning | 50 | 1,000 | 0.00% | ||
| 22 | BANK OF AMERICA CORP /DE/ | 14 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
