| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BAUPOST GROUP LLC/MA | 5,575,407 | 119,927,000 | 53.26% | ||
| 2 | BVF INC/IL | 1,387,853 | 29,908,000 | 13.28% | ||
| 3 | Assured Investment Management LLC | 1,311,043 | 28,253,000 | 12.55% | ||
| 4 | Cormorant Asset Management, LP | 589,175 | 12,697,000 | 5.64% | ||
| 5 | SENZAR ASSET MANAGEMENT, LLC | 472,300 | 10,159,000 | 4.51% | ||
| 6 | PERCEPTIVE ADVISORS LLC | 354,241 | 7,634,000 | 3.39% | ||
| 7 | Tekla Capital Management LLC | 122,835 | 2,642,000 | 1.17% | ||
| 8 | Point72 Asset Management, L.P. | 114,601 | 2,465,000 | 1.09% | ||
| 9 | SPHERA FUNDS MANAGEMENT LTD. | 108,023 | 2,328,000 | 1.03% | ||
| 10 | HIGHLAND CAPITAL MANAGEMENT LP | 79,600 | 1,715,000 | 0.76% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 63,254 | 1,361,000 | 0.60% | ||
| 12 | SANDIA HOLDINGS, LLC | 55,029 | 1,184,000 | 0.53% | ||
| 13 | SABBY MANAGEMENT, LLC | 34,000 | 733,000 | 0.33% | ||
| 14 | MORGAN STANLEY | 33,289 | 716,000 | 0.32% | ||
| 15 | MARSHALL WACE NORTH AMERICA, L.P. | 27,836 | 612,000 | 0.27% | ||
| 16 | MARSHALL WACE ASIA LTD | 27,836 | 612,000 | 0.27% | ||
| 17 | DRW Securities, LLC | 19,200 | 413,000 | 0.18% | ||
| 18 | Freedom Investment Management, Inc. | 16,081 | 346,000 | 0.15% | ||
| 19 | NJ State Employees Deferred Compensation Plan | 15,000 | 323,000 | 0.14% | ||
| 20 | Sio Capital Management, LLC | 14,224 | 306,000 | 0.14% | ||
| 21 | CITADEL ADVISORS LLC | 12,489 | 269,000 | 0.12% | ||
| 22 | DEUTSCHE BANK AG\ | 11,213 | 241,000 | 0.11% | ||
| 23 | ROYAL BANK OF CANADA | 5,181 | 112,000 | 0.05% | ||
| 24 | EcoR1 Capital, LLC | 5,025 | 108,000 | 0.05% | ||
| 25 | ADVISOR GROUP, INC. | 1,768 | 38,000 | 0.02% | ||
| 26 | ACROSPIRE INVESTMENT MANAGEMENT LLC | 1,080 | 23,000 | 0.01% | ||
| 27 | FNY PARTNERS FUND LP | 400 | 8,000 | 0.00% | ||
| 28 | ENVESTNET ASSET MANAGEMENT INC | 361 | 8,000 | 0.00% | ||
| 29 | Tower Research Capital LLC (TRC) | 300 | 6,000 | 0.00% | ||
| 30 | UBS Group AG | 200 | 4,000 | 0.00% | ||
| 31 | WELLS FARGO & COMPANY/MN | 100 | 3,000 | 0.00% | ||
| 32 | Creative Planning | 50 | 1,000 | 0.00% | ||
| 33 | BANK OF AMERICA CORP /DE/ | 14 | 0 | 0.00% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
