| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Woodford Investment Management Ltd | 5,527,525 | 291,135,000 | 18.59% | ||
| 2 | FMR LLC | 4,692,882 | 247,174,000 | 15.78% | ||
| 3 | PRICE T ROWE ASSOCIATES INC /MD/ | 3,475,196 | 183,039,000 | 11.69% | ||
| 4 | WELLINGTON MANAGEMENT GROUP LLP | 2,527,043 | 133,099,000 | 8.50% | ||
| 5 | WESTFIELD CAPITAL MANAGEMENT CO LP | 1,392,850 | 73,361,000 | 4.68% | ||
| 6 | BlackRock Fund Advisors | 1,150,206 | 60,581,000 | 3.87% | ||
| 7 | STATE STREET CORP | 1,065,977 | 56,143,000 | 3.59% | ||
| 8 | Visium Asset Management, LP | 996,887 | 52,506,000 | 3.35% | ||
| 9 | Palo Alto Investors LP | 695,918 | 36,654,000 | 2.34% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 637,387 | 33,571,000 | 2.14% | ||
| 11 | MILLENNIUM MANAGEMENT LLC | 539,913 | 28,437,000 | 1.82% | ||
| 12 | NORTHERN TRUST CORP | 484,021 | 25,493,000 | 1.63% | ||
| 13 | VANGUARD GROUP INC | 460,483 | 24,253,000 | 1.55% | ||
| 14 | CITADEL ADVISORS LLC | 417,890 | 22,011,000 | 1.41% | ||
| 15 | JENNISON ASSOCIATES LLC | 401,730 | 21,159,000 | 1.35% | ||
| 16 | Invesco Ltd. | 291,645 | 15,361,000 | 0.98% | ||
| 17 | COLUMBUS CIRCLE INVESTORS | 281,415 | 14,822,000 | 0.95% | ||
| 18 | OAK RIDGE INVESTMENTS LLC | 263,266 | 13,866,000 | 0.89% | ||
| 19 | Rock Springs Capital Management LP | 250,000 | 13,168,000 | 0.84% | ||
| 20 | MARSHALL WACE, LLP | 222,360 | 11,712,000 | 0.75% | ||
| 21 | TEACHERS ADVISORS, LLC | 203,065 | 10,695,000 | 0.68% | ||
| 22 | GEODE CAPITAL MANAGEMENT, LLC | 200,180 | 10,543,000 | 0.67% | ||
| 23 | GUGGENHEIM CAPITAL LLC | 195,538 | 10,300,000 | 0.66% | ||
| 24 | Bank of New York Mellon Corp | 192,900 | 10,160,000 | 0.65% | ||
| 25 | NORGES BANK | 189,264 | 9,968,000 | 0.64% | ||
| 26 | TURNER INVESTMENTS LLC | 173,820 | 9,155,000 | 0.58% | ||
| 27 | CREDIT SUISSE AG/ | 154,628 | 8,144,000 | 0.52% | ||
| 28 | TIAA CREF INVESTMENT MANAGEMENT LLC | 143,604 | 7,564,000 | 0.48% | ||
| 29 | PRUDENTIAL FINANCIAL INC | 137,470 | 7,241,000 | 0.46% | ||
| 30 | Informed Momentum Co LLC | 117,809 | 6,205,000 | 0.40% | ||
| 31 | SPHERA FUNDS MANAGEMENT LTD. | 115,133 | 6,064,000 | 0.39% | ||
| 32 | TWO SIGMA INVESTMENTS, LP | 111,544 | 5,875,000 | 0.38% | ||
| 33 | BlackRock Investment Management, LLC | 105,984 | 5,582,000 | 0.36% | ||
| 34 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 92,900 | 4,893,000 | 0.31% | Call | |
| 35 | Employees Retirement System of Texas | 90,000 | 4,740,000 | 0.30% | ||
| 36 | JPMORGAN CHASE & CO | 86,226 | 4,541,000 | 0.29% | ||
| 37 | PUTNAM INVESTMENTS LLC | 82,435 | 4,342,000 | 0.28% | ||
| 38 | CLOUGH CAPITAL PARTNERS L P | 69,400 | 3,655,000 | 0.23% | ||
| 39 | DEUTSCHE BANK AG\ | 66,913 | 3,523,000 | 0.22% | ||
| 40 | Point72 Asset Management, L.P. | 62,000 | 3,266,000 | 0.21% | ||
| 41 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 60,700 | 3,197,000 | 0.20% | Put | |
| 42 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 57,140 | 3,010,000 | 0.19% | ||
| 43 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 54,772 | 2,885,000 | 0.18% | ||
| 44 | AXA S.A. | 51,162 | 2,695,000 | 0.17% | ||
| 45 | ALLIANCEBERNSTEIN L.P. | 44,800 | 2,360,000 | 0.15% | ||
| 46 | AMERIPRISE FINANCIAL INC | 44,386 | 2,338,000 | 0.15% | ||
| 47 | UBS Group AG | 42,400 | 2,233,000 | 0.14% | Call | |
| 48 | WELLS FARGO & COMPANY/MN | 41,954 | 2,210,000 | 0.14% | ||
| 49 | RUSSELL FRANK CO/ | 41,903 | 2,207,000 | 0.14% | ||
| 50 | BLACKROCK ADVISORS LLC | 38,326 | 2,019,000 | 0.13% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
