| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 1,640,892 | 33,409,000 | 19.45% | ||
| 2 | FRANKLIN RESOURCES INC | 1,152,348 | 23,462,000 | 13.66% | ||
| 3 | PRICE T ROWE ASSOCIATES INC /MD/ | 830,266 | 16,904,000 | 9.84% | ||
| 4 | TimesSquare Capital Management, LLC | 811,050 | 16,513,000 | 9.61% | ||
| 5 | JANUS HENDERSON INVESTORS US LLC | 429,078 | 8,736,000 | 5.09% | ||
| 6 | SAC Capital Advisors LP | 400,000 | 8,144,000 | 4.74% | ||
| 7 | EVENTIDE ASSET MANAGEMENT, LLC | 362,400 | 7,378,000 | 4.29% | ||
| 8 | BAKER BROS. ADVISORS LP | 338,671 | 6,895,000 | 4.01% | ||
| 9 | VANGUARD GROUP INC | 277,138 | 5,642,000 | 3.28% | ||
| 10 | BlackRock Fund Advisors | 271,721 | 5,532,000 | 3.22% | ||
| 11 | GOLDMAN SACHS GROUP INC | 255,026 | 5,193,000 | 3.02% | ||
| 12 | Artal Group S.A. | 155,000 | 3,156,000 | 1.84% | ||
| 13 | Visium Asset Management, LP | 150,000 | 3,054,000 | 1.78% | ||
| 14 | STATE STREET CORP | 140,124 | 2,851,000 | 1.66% | ||
| 15 | Private Capital Advisors, Inc. | 132,000 | 2,688,000 | 1.56% | ||
| 16 | NORTHERN TRUST CORP | 122,163 | 2,488,000 | 1.45% | ||
| 17 | BlackRock Institutional Trust Company, N.A. | 115,823 | 2,358,000 | 1.37% | ||
| 18 | QVT Financial LP | 110,000 | 2,240,000 | 1.30% | ||
| 19 | FARALLON CAPITAL MANAGEMENT LLC | 95,000 | 1,934,000 | 1.13% | ||
| 20 | MILLENNIUM MANAGEMENT LLC | 86,491 | 1,761,000 | 1.03% | ||
| 21 | Invesco Ltd. | 79,996 | 1,629,000 | 0.95% | ||
| 22 | MORGAN STANLEY | 57,558 | 1,172,000 | 0.68% | ||
| 23 | GEODE CAPITAL MANAGEMENT, LLC | 53,701 | 1,093,000 | 0.64% | ||
| 24 | TIAA CREF INVESTMENT MANAGEMENT LLC | 41,209 | 839,000 | 0.49% | ||
| 25 | Bank of New York Mellon Corp | 40,311 | 820,000 | 0.48% | ||
| 26 | CREDIT SUISSE AG/ | 33,812 | 689,000 | 0.40% | ||
| 27 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 29,500 | 601,000 | 0.35% | ||
| 28 | BlackRock Investment Management, LLC | 26,863 | 547,000 | 0.32% | ||
| 29 | BLACKROCK ADVISORS LLC | 19,752 | 402,000 | 0.23% | ||
| 30 | TD ASSET MANAGEMENT INC | 19,200 | 391,000 | 0.23% | ||
| 31 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 17,441 | 355,000 | 0.21% | ||
| 32 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 18,400 | 352,000 | 0.20% | ||
| 33 | Healthcare Value Capital, LLC | 16,464 | 335,000 | 0.20% | ||
| 34 | TEACHERS ADVISORS, LLC | 15,284 | 311,000 | 0.18% | ||
| 35 | STONERIDGE INVESTMENT PARTNERS LLC | 14,345 | 292,000 | 0.17% | ||
| 36 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 13,000 | 265,000 | 0.15% | ||
| 37 | METROPOLITAN LIFE INSURANCE CO/NY | 7,976 | 162,000 | 0.09% | ||
| 38 | Swiss National Bank | 7,700 | 157,000 | 0.09% | ||
| 39 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 7,648 | 156,000 | 0.09% | ||
| 40 | Nationwide Fund Advisors | 7,467 | 152,000 | 0.09% | ||
| 41 | AMERICAN INTERNATIONAL GROUP, INC. | 7,037 | 143,274 | 0.08% | ||
| 42 | DEUTSCHE BANK AG\ | 6,866 | 139,000 | 0.08% | ||
| 43 | CITIGROUP INC | 5,951 | 122,000 | 0.07% | ||
| 44 | STRS OHIO | 3,500 | 71,000 | 0.04% | ||
| 45 | BARCLAYS PLC | 2,766 | 55,000 | 0.03% | ||
| 46 | UBS AG | 2,072 | 43,000 | 0.03% | ||
| 47 | BlackRock Group LTD | 2,043 | 42,000 | 0.02% | ||
| 48 | Quantbot Technologies LP | 1,600 | 32,000 | 0.02% | ||
| 49 | SMITH ASSET MANAGEMENT GROUP LP | 1,404 | 29,000 | 0.02% | ||
| 50 | CANADA PENSION PLAN INVESTMENT BOARD | 700 | 14,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
