| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 29,443,300 | 807,924,000 | 44.86% | ||
| 2 | FMR LLC | 6,567,800 | 180,220,000 | 10.01% | ||
| 3 | Capital Research Global Investors | 3,532,000 | 96,918,000 | 5.38% | ||
| 4 | FIRST MANHATTAN CO. LLC. | 3,498,238 | 95,991,000 | 5.33% | ||
| 5 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 2,191,600 | 60,138,000 | 3.34% | Put | |
| 6 | NORTH TIDE CAPITAL, LLC | 2,000,000 | 54,880,000 | 3.05% | ||
| 7 | VANGUARD GROUP INC | 1,646,978 | 45,194,000 | 2.51% | ||
| 8 | Camber Capital Management LP | 1,000,000 | 27,440,000 | 1.52% | ||
| 9 | Gotham Asset Management, LLC | 964,477 | 26,465,000 | 1.47% | ||
| 10 | Point72 Asset Management, L.P. | 700,000 | 19,208,000 | 1.07% | Put | |
| 11 | CHUBB CORP | 700,000 | 19,207,000 | 1.07% | ||
| 12 | BlackRock Institutional Trust Company, N.A. | 696,708 | 19,118,000 | 1.06% | ||
| 13 | BlackRock Fund Advisors | 615,048 | 16,877,000 | 0.94% | ||
| 14 | Ninety One UK Ltd | 513,790 | 14,098,000 | 0.78% | ||
| 15 | STATE STREET CORP | 482,421 | 13,236,000 | 0.73% | ||
| 16 | NORGES BANK | 459,398 | 12,605,000 | 0.70% | ||
| 17 | BARCLAYS PLC | 413,500 | 11,164,000 | 0.62% | Put | |
| 18 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 396,800 | 10,888,000 | 0.60% | Call | |
| 19 | Spot Trading L.L.C | 382,900 | 10,507,000 | 0.58% | Put | |
| 20 | NORTHERN TRUST CORP | 315,240 | 8,651,000 | 0.48% | ||
| 21 | GLG LLC | 308,747 | 8,472,000 | 0.47% | ||
| 22 | Passport Capital, LLC | 300,000 | 8,232,000 | 0.46% | Put | PRN |
| 23 | EverPoint Asset Management, LLC | 300,000 | 8,232,000 | 0.46% | ||
| 24 | GOLDMAN SACHS GROUP INC | 270,900 | 7,433,000 | 0.41% | Put | |
| 25 | Spot Trading L.L.C | 270,200 | 7,414,000 | 0.41% | Call | |
| 26 | HBK INVESTMENTS L P | 243,000 | 6,668,000 | 0.37% | Put | |
| 27 | GOLDMAN SACHS GROUP INC | 222,628 | 6,109,000 | 0.34% | ||
| 28 | LAZARD ASSET MANAGEMENT LLC | 217,619 | 5,971,000 | 0.33% | ||
| 29 | Sculptor Capital LP | 213,500 | 5,858,000 | 0.33% | Put | |
| 30 | Bank of New York Mellon Corp | 197,839 | 5,429,000 | 0.30% | ||
| 31 | AUXIER ASSET MANAGEMENT LLC | 195,073 | 5,353,000 | 0.30% | ||
| 32 | GOLDMAN SACHS GROUP INC | 188,300 | 5,167,000 | 0.29% | Call | |
| 33 | PNC FINANCIAL SERVICES GROUP, INC. | 181,368 | 4,976,000 | 0.28% | ||
| 34 | INTEGRAL DERIVATIVES, LLC | 176,100 | 4,832,000 | 0.27% | Call | |
| 35 | Hutchin Hill Capital, LP | 171,000 | 4,692,000 | 0.26% | ||
| 36 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 166,803 | 4,578,000 | 0.25% | ||
| 37 | Harvest Capital Strategies LLC | 155,000 | 4,253,000 | 0.24% | ||
| 38 | WELLS FARGO & COMPANY/MN | 147,690 | 4,052,000 | 0.22% | ||
| 39 | MORGAN STANLEY | 146,982 | 4,034,000 | 0.22% | ||
| 40 | GEODE CAPITAL MANAGEMENT, LLC | 133,470 | 3,662,000 | 0.20% | ||
| 41 | AQR CAPITAL MANAGEMENT LLC | 127,068 | 3,487,000 | 0.19% | ||
| 42 | BESSEMER GROUP INC | 125,000 | 3,430,000 | 0.19% | ||
| 43 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 124,171 | 3,407,000 | 0.19% | ||
| 44 | Sculptor Capital LP | 121,500 | 3,334,000 | 0.19% | ||
| 45 | D. E. Shaw & Co., Inc. | 120,500 | 3,307,000 | 0.18% | Put | |
| 46 | UBS AG | 119,766 | 3,286,000 | 0.18% | ||
| 47 | SCOUT INVESTMENTS, INC. | 116,425 | 3,195,000 | 0.18% | ||
| 48 | Atria Investments, Inc | 115,771 | 3,177,000 | 0.18% | ||
| 49 | Diversified Investment Strategies, LLC | 114,650 | 3,146,000 | 0.17% | ||
| 50 | D. E. Shaw & Co., Inc. | 114,579 | 3,144,000 | 0.17% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
