| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 29,443,300 | 337,126,000 | 44.76% | ||
| 2 | FMR LLC | 9,575,252 | 109,637,000 | 14.56% | ||
| 3 | VANGUARD GROUP INC | 2,257,048 | 25,843,000 | 3.43% | ||
| 4 | Melvin Capital Management LP | 1,690,000 | 19,351,000 | 2.57% | ||
| 5 | State of New Jersey Common Pension Fund D | 1,600,000 | 18,320,000 | 2.43% | ||
| 6 | BANK OF AMERICA CORP /DE/ | 1,078,799 | 12,352,000 | 1.64% | ||
| 7 | D. E. Shaw & Co., Inc. | 1,078,129 | 12,345,000 | 1.64% | ||
| 8 | CITADEL ADVISORS LLC | 880,258 | 10,079,000 | 1.34% | ||
| 9 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 875,400 | 10,023,000 | 1.33% | Put | |
| 10 | BlackRock Fund Advisors | 837,707 | 9,592,000 | 1.27% | ||
| 11 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 810,800 | 9,284,000 | 1.23% | Call | |
| 12 | BlackRock Institutional Trust Company, N.A. | 703,469 | 8,055,000 | 1.07% | ||
| 13 | Assured Investment Management LLC | 675,000 | 7,729,000 | 1.03% | ||
| 14 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 600,000 | 6,870,000 | 0.91% | ||
| 15 | 12 West Capital Management LP | 598,388 | 6,852,000 | 0.91% | ||
| 16 | MORGAN STANLEY | 568,678 | 6,512,000 | 0.86% | ||
| 17 | AMERICAN CENTURY COMPANIES INC | 561,160 | 6,425,000 | 0.85% | ||
| 18 | Firefly Value Partners, LP | 537,000 | 6,149,000 | 0.82% | Put | |
| 19 | INDUS CAPITAL PARTNERS, LLC | 506,805 | 5,803,000 | 0.77% | ||
| 20 | EverPoint Asset Management, LLC | 500,000 | 5,725,000 | 0.76% | Put | |
| 21 | Hound Partners, LLC | 500,079 | 5,725,000 | 0.76% | ||
| 22 | STATE STREET CORP | 491,758 | 5,626,000 | 0.75% | ||
| 23 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 471,831 | 5,402,000 | 0.72% | ||
| 24 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 414,713 | 4,749,000 | 0.63% | ||
| 25 | Melvin Capital Management LP | 400,000 | 4,580,000 | 0.61% | Put | |
| 26 | Gotham Asset Management, LLC | 400,022 | 4,580,000 | 0.61% | ||
| 27 | Ninety One UK Ltd | 360,163 | 4,124,000 | 0.55% | ||
| 28 | NORTHERN TRUST CORP | 328,773 | 3,765,000 | 0.50% | ||
| 29 | BARROW HANLEY MEWHINNEY & STRAUSS LLC | 265,922 | 3,045,000 | 0.40% | ||
| 30 | Permit Capital, LLC | 251,150 | 2,876,000 | 0.38% | ||
| 31 | HIGHLAND CAPITAL MANAGEMENT LP | 235,500 | 2,696,000 | 0.36% | ||
| 32 | WOLVERINE TRADING LP /BD | 230,000 | 2,634,000 | 0.35% | Put | |
| 33 | GOLDMAN SACHS GROUP INC | 206,500 | 2,364,000 | 0.31% | Call | |
| 34 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 197,171 | 2,258,000 | 0.30% | ||
| 35 | WOLVERINE TRADING LP /BD | 190,600 | 2,182,000 | 0.29% | Call | |
| 36 | Bank of New York Mellon Corp | 189,076 | 2,165,000 | 0.29% | ||
| 37 | GEODE CAPITAL MANAGEMENT, LLC | 183,761 | 2,104,000 | 0.28% | ||
| 38 | Spot Trading L.L.C | 180,500 | 2,067,000 | 0.27% | Call | |
| 39 | NOMURA HOLDINGS INC | 182,300 | 2,066,000 | 0.27% | Put | |
| 40 | BARCLAYS PLC | 179,100 | 2,051,000 | 0.27% | Call | |
| 41 | CITADEL ADVISORS LLC | 176,700 | 2,023,000 | 0.27% | Put | |
| 42 | Hutchin Hill Capital, LP | 155,200 | 1,777,000 | 0.24% | ||
| 43 | WELLS FARGO & COMPANY/MN | 153,173 | 1,754,000 | 0.23% | ||
| 44 | GOLDMAN SACHS GROUP INC | 140,427 | 1,608,000 | 0.21% | ||
| 45 | INDUS CAPITAL PARTNERS, LLC | 131,900 | 1,510,000 | 0.20% | Call | |
| 46 | FEDERATED HERMES, INC. | 129,132 | 1,479,000 | 0.20% | ||
| 47 | CITIGROUP INC | 123,500 | 1,414,000 | 0.19% | Put | |
| 48 | NORGES BANK | 119,000 | 1,363,000 | 0.18% | ||
| 49 | CITADEL ADVISORS LLC | 118,200 | 1,353,000 | 0.18% | Call | |
| 50 | MIZUHO SECURITIES USA LLC | 96,600 | 1,335,000 | 0.18% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
