| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 29,443,300 | 671,307,000 | 43.00% | ||
| 2 | FMR LLC | 8,166,200 | 186,190,000 | 11.93% | ||
| 3 | Assured Investment Management LLC | 2,000,000 | 45,600,000 | 2.92% | ||
| 4 | Point72 Asset Management, L.P. | 1,932,595 | 44,063,000 | 2.82% | ||
| 5 | VANGUARD GROUP INC | 1,916,105 | 43,687,000 | 2.80% | ||
| 6 | Clearline Capital LP | 1,615,183 | 36,826,000 | 2.36% | ||
| 7 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,365,700 | 31,138,000 | 1.99% | Call | |
| 8 | Hound Partners, LLC | 1,215,863 | 27,722,000 | 1.78% | ||
| 9 | D. E. Shaw & Co., Inc. | 1,167,188 | 26,612,000 | 1.70% | ||
| 10 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,066,100 | 24,307,000 | 1.56% | Put | |
| 11 | Ionic Capital Management LLC | 1,000,000 | 22,800,000 | 1.46% | Put | |
| 12 | BlackRock Fund Advisors | 745,220 | 16,991,000 | 1.09% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 686,067 | 15,642,000 | 1.00% | ||
| 14 | EAGLE ASSET MANAGEMENT INC | 578,846 | 13,197,000 | 0.85% | ||
| 15 | GOLDMAN SACHS GROUP INC | 564,300 | 12,866,000 | 0.82% | Put | |
| 16 | Spot Trading L.L.C | 555,000 | 12,654,000 | 0.81% | Put | |
| 17 | Point72 Asset Management, L.P. | 550,000 | 12,540,000 | 0.80% | Call | |
| 18 | SAMLYN CAPITAL, LLC | 527,000 | 12,016,000 | 0.77% | ||
| 19 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 500,361 | 11,409,000 | 0.73% | ||
| 20 | STATE STREET CORP | 487,707 | 11,122,000 | 0.71% | ||
| 21 | MORGAN STANLEY | 444,249 | 10,128,000 | 0.65% | ||
| 22 | BANK OF AMERICA CORP /DE/ | 440,000 | 10,032,000 | 0.64% | Put | |
| 23 | WELLS FARGO & COMPANY/MN | 411,683 | 9,387,000 | 0.60% | ||
| 24 | GOLDMAN SACHS GROUP INC | 408,556 | 9,315,000 | 0.60% | ||
| 25 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 400,000 | 9,120,000 | 0.58% | ||
| 26 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 361,599 | 8,245,000 | 0.53% | ||
| 27 | BANK OF AMERICA CORP /DE/ | 350,497 | 7,991,000 | 0.51% | ||
| 28 | NORTHERN TRUST CORP | 326,392 | 7,442,000 | 0.48% | ||
| 29 | CITADEL ADVISORS LLC | 308,032 | 7,023,000 | 0.45% | ||
| 30 | BRIDGER MANAGEMENT, LLC | 300,000 | 6,840,000 | 0.44% | Put | |
| 31 | BARCLAYS PLC | 310,618 | 6,834,000 | 0.44% | ||
| 32 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 280,271 | 6,390,000 | 0.41% | ||
| 33 | Spot Trading L.L.C | 264,700 | 6,035,000 | 0.39% | Call | |
| 34 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 257,138 | 5,863,000 | 0.38% | ||
| 35 | Ninety One UK Ltd | 255,993 | 5,837,000 | 0.37% | ||
| 36 | Sculptor Capital LP | 243,600 | 5,554,000 | 0.36% | ||
| 37 | RAYMOND JAMES & ASSOCIATES | 241,117 | 5,497,000 | 0.35% | ||
| 38 | Nokomis Capital, L.L.C. | 231,200 | 5,271,000 | 0.34% | Put | |
| 39 | Anandar Capital Management LP | 215,000 | 4,902,000 | 0.31% | Put | |
| 40 | Russell Clark Investment Management Ltd | 210,300 | 4,795,000 | 0.31% | ||
| 41 | PEAK6 Group LLC | 183,900 | 4,193,000 | 0.27% | Call | |
| 42 | Informed Momentum Co LLC | 180,213 | 4,109,000 | 0.26% | ||
| 43 | Quantitative Investment Management, LLC | 175,200 | 3,994,000 | 0.26% | ||
| 44 | Permit Capital, LLC | 172,400 | 3,931,000 | 0.25% | ||
| 45 | GEODE CAPITAL MANAGEMENT, LLC | 168,268 | 3,836,000 | 0.25% | ||
| 46 | Bank of New York Mellon Corp | 166,260 | 3,791,000 | 0.24% | ||
| 47 | Sculptor Capital LP | 159,900 | 3,646,000 | 0.23% | Call | |
| 48 | RAIFF PARTNERS INC | 155,000 | 3,534,000 | 0.23% | ||
| 49 | Sculptor Capital LP | 151,700 | 3,459,000 | 0.22% | Put | |
| 50 | Laurion Capital Management LP | 150,000 | 3,420,000 | 0.22% | Put |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
