| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 29,443,300 | 731,372,000 | 43.12% | ||
| 2 | FMR LLC | 5,981,800 | 148,588,000 | 8.76% | ||
| 3 | FIRST MANHATTAN CO. LLC. | 2,766,645 | 68,723,000 | 4.05% | ||
| 4 | Capital Research Global Investors | 3,532,000 | 58,490,000 | 3.45% | ||
| 5 | MILLENNIUM MANAGEMENT LLC | 1,894,768 | 47,066,000 | 2.78% | ||
| 6 | NORTH TIDE CAPITAL, LLC | 1,700,000 | 42,228,000 | 2.49% | ||
| 7 | VANGUARD GROUP INC | 1,681,208 | 41,761,000 | 2.46% | ||
| 8 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,521,500 | 37,794,000 | 2.23% | Put | |
| 9 | Camber Capital Management LP | 1,146,741 | 28,485,000 | 1.68% | ||
| 10 | PUTNAM INVESTMENTS LLC | 1,077,898 | 26,775,000 | 1.58% | ||
| 11 | BlackRock Fund Advisors | 722,178 | 17,939,000 | 1.06% | ||
| 12 | CHUBB CORP | 700,000 | 17,388,000 | 1.03% | ||
| 13 | BlackRock Institutional Trust Company, N.A. | 687,496 | 17,077,000 | 1.01% | ||
| 14 | Gotham Asset Management, LLC | 687,362 | 17,074,000 | 1.01% | ||
| 15 | EverPoint Asset Management, LLC | 550,000 | 13,662,000 | 0.81% | Call | |
| 16 | EverPoint Asset Management, LLC | 510,000 | 12,668,000 | 0.75% | ||
| 17 | Spot Trading L.L.C | 499,700 | 12,413,000 | 0.73% | Put | |
| 18 | Ninety One UK Ltd | 478,593 | 11,888,000 | 0.70% | ||
| 19 | STATE STREET CORP | 472,711 | 11,739,000 | 0.69% | ||
| 20 | Point72 Asset Management, L.P. | 470,400 | 11,685,000 | 0.69% | Put | |
| 21 | Melvin Capital Management LP | 450,000 | 11,178,000 | 0.66% | Put | |
| 22 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 423,800 | 10,527,000 | 0.62% | Call | |
| 23 | HBK INVESTMENTS L P | 405,000 | 10,060,000 | 0.59% | Put | |
| 24 | NORGES BANK | 343,015 | 8,520,000 | 0.50% | ||
| 25 | NORTHERN TRUST CORP | 305,561 | 7,591,000 | 0.45% | ||
| 26 | Passport Capital, LLC | 300,000 | 7,452,000 | 0.44% | Put | |
| 27 | D. E. Shaw & Co., Inc. | 288,758 | 7,172,000 | 0.42% | ||
| 28 | MILLENNIUM MANAGEMENT LLC | 283,800 | 7,050,000 | 0.42% | Call | |
| 29 | Point72 Asset Management, L.P. | 249,300 | 6,193,000 | 0.37% | ||
| 30 | LAZARD ASSET MANAGEMENT LLC | 238,319 | 5,919,000 | 0.35% | ||
| 31 | ADDISON CLARK MANAGEMENT, L.L.C. | 235,165 | 5,841,000 | 0.34% | ||
| 32 | Boston Partners | 222,596 | 5,529,000 | 0.33% | ||
| 33 | PANAGORA ASSET MANAGEMENT INC | 219,544 | 5,453,000 | 0.32% | ||
| 34 | AGF INVESTMENTS INC. | 215,548 | 5,351,000 | 0.32% | ||
| 35 | GOLDMAN SACHS GROUP INC | 214,100 | 5,318,000 | 0.31% | Call | |
| 36 | Sculptor Capital LP | 213,500 | 5,303,000 | 0.31% | Put | |
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 210,636 | 5,232,000 | 0.31% | ||
| 38 | Bank of New York Mellon Corp | 201,789 | 5,013,000 | 0.30% | ||
| 39 | Ellis Lake Capital, LLC | 200,000 | 4,968,000 | 0.29% | Put | |
| 40 | Apollo Management Holdings, L.P. | 200,000 | 4,968,000 | 0.29% | Put | |
| 41 | AUXIER ASSET MANAGEMENT LLC | 194,673 | 4,836,000 | 0.29% | ||
| 42 | GLG Partners LP | 193,100 | 4,797,000 | 0.28% | Call | |
| 43 | BANK OF AMERICA CORP /DE/ | 185,948 | 4,619,000 | 0.27% | ||
| 44 | Sculptor Capital LP | 181,500 | 4,508,000 | 0.27% | ||
| 45 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 175,174 | 4,352,000 | 0.26% | ||
| 46 | PNC FINANCIAL SERVICES GROUP, INC. | 171,394 | 4,258,000 | 0.25% | ||
| 47 | SCOUT INVESTMENTS, INC. | 169,550 | 4,212,000 | 0.25% | ||
| 48 | GOLDMAN SACHS GROUP INC | 169,400 | 4,208,000 | 0.25% | Put | |
| 49 | AHL Partners LLP | 163,403 | 4,059,000 | 0.24% | ||
| 50 | Brandywine Global Investment Management, LLC | 162,937 | 4,048,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
