| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 29,443,300 | 303,855,000 | 48.81% | ||
| 2 | FMR LLC | 9,569,152 | 98,754,000 | 15.86% | ||
| 3 | VANGUARD GROUP INC | 2,657,830 | 27,429,000 | 4.41% | ||
| 4 | State of New Jersey Common Pension Fund D | 1,550,000 | 15,996,000 | 2.57% | ||
| 5 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 868,400 | 8,962,000 | 1.44% | Call | |
| 6 | Hound Partners, LLC | 800,079 | 8,257,000 | 1.33% | ||
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 800,000 | 8,256,000 | 1.33% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 726,520 | 7,498,000 | 1.20% | ||
| 9 | Melvin Capital Management LP | 710,000 | 7,327,000 | 1.18% | ||
| 10 | BlackRock Fund Advisors | 704,699 | 7,272,000 | 1.17% | ||
| 11 | HUSSMAN STRATEGIC ADVISORS, INC. | 600,000 | 6,192,000 | 0.99% | ||
| 12 | 12 West Capital Management LP | 598,388 | 6,175,000 | 0.99% | ||
| 13 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 550,100 | 5,677,000 | 0.91% | Put | |
| 14 | Firefly Value Partners, LP | 537,000 | 5,542,000 | 0.89% | Put | |
| 15 | AMERICAN CENTURY COMPANIES INC | 534,663 | 5,518,000 | 0.89% | ||
| 16 | MORGAN STANLEY | 520,849 | 5,375,000 | 0.86% | ||
| 17 | D. E. Shaw & Co., Inc. | 516,398 | 5,329,000 | 0.86% | ||
| 18 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 462,009 | 4,768,000 | 0.77% | ||
| 19 | STATE STREET CORP | 461,344 | 4,759,000 | 0.76% | ||
| 20 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 407,487 | 4,206,000 | 0.68% | ||
| 21 | Gotham Asset Management, LLC | 372,038 | 3,839,000 | 0.62% | ||
| 22 | Ninety One UK Ltd | 360,163 | 3,717,000 | 0.60% | ||
| 23 | NORTHERN TRUST CORP | 317,903 | 3,281,000 | 0.53% | ||
| 24 | Permit Capital, LLC | 251,150 | 2,592,000 | 0.42% | ||
| 25 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 187,871 | 1,939,000 | 0.31% | ||
| 26 | Spot Trading L.L.C | 182,000 | 1,878,000 | 0.30% | Call | |
| 27 | Allianz Asset Management GmbH | 179,418 | 1,852,000 | 0.30% | ||
| 28 | GEODE CAPITAL MANAGEMENT, LLC | 179,228 | 1,849,000 | 0.30% | ||
| 29 | GOLDMAN SACHS GROUP INC | 176,774 | 1,824,000 | 0.29% | ||
| 30 | WOLVERINE TRADING LP /BD | 159,700 | 1,637,000 | 0.26% | Put | |
| 31 | CITADEL ADVISORS LLC | 147,700 | 1,524,000 | 0.24% | Put | |
| 32 | Jefferies Group LLC | 145,840 | 1,505,000 | 0.24% | ||
| 33 | CREDIT SUISSE AG/ | 144,685 | 1,493,000 | 0.24% | ||
| 34 | Bank of New York Mellon Corp | 142,670 | 1,472,000 | 0.24% | ||
| 35 | BANK OF MONTREAL /CAN/ | 125,200 | 1,292,000 | 0.21% | ||
| 36 | BANK OF MONTREAL /CAN/ | 125,200 | 1,292,000 | 0.21% | Put | |
| 37 | BANK OF AMERICA CORP /DE/ | 125,000 | 1,290,000 | 0.21% | Call | |
| 38 | WOLVERINE ASSET MANAGEMENT LLC | 123,300 | 1,272,000 | 0.20% | Put | |
| 39 | MIZUHO SECURITIES USA LLC | 119,700 | 1,235,000 | 0.20% | ||
| 40 | CITADEL ADVISORS LLC | 119,100 | 1,229,000 | 0.20% | Call | |
| 41 | HIGHLAND CAPITAL MANAGEMENT LP | 116,500 | 1,202,000 | 0.19% | ||
| 42 | Jefferies Group LLC | 113,700 | 1,173,000 | 0.19% | Put | |
| 43 | DIMENSIONAL FUND ADVISORS LP | 110,890 | 1,144,000 | 0.18% | ||
| 44 | MIZUHO SECURITIES USA LLC | 119,700 | 1,089,000 | 0.17% | Put | |
| 45 | WOLVERINE TRADING LP /BD | 105,500 | 1,081,000 | 0.17% | Call | |
| 46 | BlackRock Investment Management, LLC | 103,289 | 1,066,000 | 0.17% | ||
| 47 | CREDIT SUISSE AG/ | 100,000 | 1,032,000 | 0.17% | Put | |
| 48 | WELLS FARGO & COMPANY/MN | 99,677 | 1,029,000 | 0.17% | ||
| 49 | FEDERATED HERMES, INC. | 98,337 | 1,015,000 | 0.16% | ||
| 50 | NORGES BANK | 100,000 | 986,000 | 0.16% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
