| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Artal Group S.A. | 29,443,300 | 187,848,000 | 46.91% | ||
| 2 | FMR LLC | 6,067,900 | 38,713,000 | 9.67% | ||
| 3 | VANGUARD GROUP INC | 1,848,389 | 11,793,000 | 2.94% | ||
| 4 | Kohlberg Kravis Roberts & Co. L.P. | 1,500,000 | 9,570,000 | 2.39% | ||
| 5 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,111,900 | 7,094,000 | 1.77% | Put | |
| 6 | Tourbillon Capital Partners, L.P. | 1,004,800 | 6,411,000 | 1.60% | Call | |
| 7 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 878,500 | 5,605,000 | 1.40% | Call | |
| 8 | Point72 Asset Management, L.P. | 814,700 | 5,198,000 | 1.30% | ||
| 9 | Pomelo Capital LLC | 806,100 | 5,143,000 | 1.28% | ||
| 10 | Pomelo Capital LLC | 3,083,500 | 5,022,000 | 1.25% | Put | |
| 11 | MORGAN STANLEY | 748,220 | 4,774,000 | 1.19% | ||
| 12 | BlackRock Fund Advisors | 724,002 | 4,619,000 | 1.15% | ||
| 13 | CHUBB CORP | 700,000 | 4,466,000 | 1.12% | ||
| 14 | Ninety One UK Ltd | 698,993 | 4,460,000 | 1.11% | ||
| 15 | BlackRock Institutional Trust Company, N.A. | 690,088 | 4,403,000 | 1.10% | ||
| 16 | GOLDMAN SACHS GROUP INC | 655,800 | 4,184,000 | 1.04% | Put | |
| 17 | FEDERATED HERMES, INC. | 617,371 | 3,939,000 | 0.98% | ||
| 18 | GOLDMAN SACHS GROUP INC | 614,816 | 3,923,000 | 0.98% | ||
| 19 | Marble Arch Investments, LP | 574,975 | 3,668,000 | 0.92% | ||
| 20 | WELLS FARGO & COMPANY/MN | 504,910 | 3,221,000 | 0.80% | ||
| 21 | Spot Trading L.L.C | 500,800 | 3,195,000 | 0.80% | Put | |
| 22 | STATE STREET CORP | 491,504 | 3,136,000 | 0.78% | ||
| 23 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 471,017 | 3,006,000 | 0.75% | ||
| 24 | WOLVERINE ASSET MANAGEMENT LLC | 4,206 | 2,805,000 | 0.70% | Put | |
| 25 | HAP Trading, LLC | 200,000 | 2,770,000 | 0.69% | Put | |
| 26 | MIZUHO SECURITIES USA LLC | 159,500 | 2,726,000 | 0.68% | Put | |
| 27 | Lapides Asset Management, LLC | 348,100 | 2,221,000 | 0.55% | ||
| 28 | FIRST MANHATTAN CO. LLC. | 326,663 | 2,084,000 | 0.52% | ||
| 29 | BARCLAYS PLC | 337,576 | 2,026,000 | 0.51% | ||
| 30 | EverPoint Asset Management, LLC | 310,726 | 1,982,000 | 0.49% | ||
| 31 | NORTHERN TRUST CORP | 309,443 | 1,975,000 | 0.49% | ||
| 32 | BARROW HANLEY MEWHINNEY & STRAUSS LLC | 304,600 | 1,943,000 | 0.49% | ||
| 33 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 289,671 | 1,848,000 | 0.46% | ||
| 34 | WOLVERINE ASSET MANAGEMENT LLC | 288,636 | 1,841,000 | 0.46% | ||
| 35 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 255,900 | 1,633,000 | 0.41% | ||
| 36 | Atria Investments, Inc | 10 | 1,586,000 | 0.40% | ||
| 37 | Sculptor Capital LP | 243,600 | 1,554,000 | 0.39% | ||
| 38 | Sculptor Capital LP | 242,800 | 1,549,000 | 0.39% | Put | |
| 39 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 225,455 | 1,438,000 | 0.36% | ||
| 40 | GROUP ONE TRADING LLC | 211,441 | 1,349,000 | 0.34% | ||
| 41 | GUGGENHEIM CAPITAL LLC | 191,995 | 1,225,000 | 0.31% | ||
| 42 | CANADA PENSION PLAN INVESTMENT BOARD | 181,500 | 1,158,000 | 0.29% | ||
| 43 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 180,394 | 1,150,000 | 0.29% | ||
| 44 | GOLDMAN SACHS GROUP INC | 178,400 | 1,138,000 | 0.28% | Call | |
| 45 | GEODE CAPITAL MANAGEMENT, LLC | 176,932 | 1,128,000 | 0.28% | ||
| 46 | SCOUT INVESTMENTS, INC. | 171,950 | 1,097,000 | 0.27% | ||
| 47 | Bank of New York Mellon Corp | 167,476 | 1,068,000 | 0.27% | ||
| 48 | MIZUHO SECURITIES USA LLC | 159,500 | 1,018,000 | 0.25% | ||
| 49 | UBS Group AG | 150,907 | 963,000 | 0.24% | ||
| 50 | Spot Trading L.L.C | 147,582 | 942,000 | 0.24% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
