| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | JANUS HENDERSON INVESTORS US LLC | 8,709,365 | 148,669,000 | 12.37% | ||
| 2 | FMR LLC | 4,825,520 | 82,372,000 | 6.85% | ||
| 3 | VANGUARD GROUP INC | 4,086,695 | 69,760,000 | 5.80% | ||
| 4 | Tamarack Capital Management, LLC | 4,000,000 | 68,280,000 | 5.68% | ||
| 5 | GOLDMAN SACHS GROUP INC | 3,716,033 | 63,433,000 | 5.28% | ||
| 6 | ArrowMark Colorado Holdings LLC | 3,150,275 | 53,775,000 | 4.47% | ||
| 7 | WELLINGTON MANAGEMENT GROUP LLP | 2,722,461 | 46,472,000 | 3.87% | ||
| 8 | BlackRock Institutional Trust Company, N.A. | 2,633,623 | 44,956,000 | 3.74% | ||
| 9 | DEERFIELD MANAGEMENT COMPANY, L.P. | 2,349,351 | 40,103,000 | 3.34% | ||
| 10 | Clearbridge Investments, LLC | 2,116,279 | 36,125,000 | 3.01% | ||
| 11 | Bank of New York Mellon Corp | 1,775,895 | 30,314,000 | 2.52% | ||
| 12 | BlackRock Fund Advisors | 1,643,129 | 28,048,000 | 2.33% | ||
| 13 | PALISADE CAPITAL MANAGEMENT, LP | 1,629,329 | 27,813,000 | 2.31% | ||
| 14 | Essex Woodlands Management, Inc. | 1,257,468 | 26,843,000 | 2.23% | ||
| 15 | WELLS FARGO & COMPANY/MN | 1,498,944 | 25,587,000 | 2.13% | ||
| 16 | KING LUTHER CAPITAL MANAGEMENT CORP | 1,382,317 | 23,596,000 | 1.96% | ||
| 17 | STATE STREET CORP | 1,106,487 | 18,885,000 | 1.57% | ||
| 18 | Polar Capital LLP | 1,101,000 | 18,793,000 | 1.56% | ||
| 19 | MACKENZIE FINANCIAL CORP | 1,036,300 | 17,690,000 | 1.47% | ||
| 20 | BANK OF AMERICA CORP /DE/ | 939,018 | 16,029,000 | 1.33% | ||
| 21 | EAGLE ASSET MANAGEMENT INC | 899,040 | 15,346,000 | 1.28% | ||
| 22 | MILLENNIUM MANAGEMENT LLC | 889,553 | 15,185,000 | 1.26% | ||
| 23 | NORTHERN TRUST CORP | 863,046 | 14,733,000 | 1.23% | ||
| 24 | KORNITZER CAPITAL MANAGEMENT INC /KS | 789,785 | 13,482,000 | 1.12% | ||
| 25 | FIL Ltd | 770,576 | 13,154,000 | 1.09% | ||
| 26 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 750,000 | 12,803,000 | 1.07% | ||
| 27 | Cortina Asset Management, LLC | 732,575 | 12,505,000 | 1.04% | ||
| 28 | BANK OF MONTREAL /CAN/ | 622,460 | 10,626,000 | 0.88% | ||
| 29 | AMUNDI ASSET MANAGEMENT US, INC. | 598,774 | 10,221,000 | 0.85% | ||
| 30 | HealthCor Management, L.P. | 575,800 | 9,829,000 | 0.82% | ||
| 31 | PERCEPTIVE ADVISORS LLC | 565,000 | 9,645,000 | 0.80% | ||
| 32 | Tekla Capital Management LLC | 551,000 | 9,406,000 | 0.78% | ||
| 33 | CLEARBRIDGE, LLC | 535,900 | 9,148,000 | 0.76% | ||
| 34 | Asset Management One Co., Ltd. | 526,371 | 8,858,000 | 0.74% | ||
| 35 | TCW GROUP INC | 486,903 | 8,311,000 | 0.69% | ||
| 36 | CITY NATIONAL BANK | 422,114 | 7,206,000 | 0.60% | ||
| 37 | WADDELL & REED FINANCIAL INC | 421,782 | 7,200,000 | 0.60% | ||
| 38 | BLACKROCK ADVISORS LLC | 421,039 | 7,187,000 | 0.60% | ||
| 39 | GEODE CAPITAL MANAGEMENT, LLC | 405,614 | 6,923,000 | 0.58% | ||
| 40 | ALTRINSIC GLOBAL ADVISORS LLC | 400,000 | 6,828,000 | 0.57% | ||
| 41 | AXA S.A. | 368,070 | 6,283,000 | 0.52% | ||
| 42 | STIFEL FINANCIAL CORP | 332,418 | 5,675,000 | 0.47% | ||
| 43 | First Light Asset Management, LLC | 277,264 | 4,733,000 | 0.39% | ||
| 44 | Nuveen Asset Management, LLC | 249,917 | 4,266,000 | 0.35% | ||
| 45 | KENNEDY CAPITAL MANAGEMENT LLC | 229,373 | 3,915,000 | 0.33% | ||
| 46 | TIAA CREF INVESTMENT MANAGEMENT LLC | 225,991 | 3,858,000 | 0.32% | ||
| 47 | GAM Holding AG | 209,700 | 3,580,000 | 0.30% | ||
| 48 | BlackRock Investment Management, LLC | 199,336 | 3,403,000 | 0.28% | ||
| 49 | Rhenman & Partners Asset Management AB | 194,000 | 3,312,000 | 0.28% | ||
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 186,508 | 3,184,000 | 0.26% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
