| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | BIOGEN INC | 487,432 | 196,893,000 | 8.21% | ||
| 2 | GILEAD SCIENCES INC | 1,304,407 | 152,720,000 | 6.37% | ||
| 3 | CELGENE CORP | 1,257,558 | 145,543,000 | 6.07% | ||
| 4 | BIOMARIN | 965,877 | 132,113,000 | 5.51% | ||
| 5 | ALEXION PHARMACEUTIC | 657,525 | 118,861,000 | 4.96% | ||
| 6 | INCYTE | 910,114 | 94,843,000 | 3.96% | ||
| 7 | REGENERON PHARMACEUTICALS | 174,900 | 89,222,000 | 3.72% | ||
| 8 | AMGEN INC | 566,497 | 86,969,000 | 3.63% | ||
| 9 | HALOZYME THERAPEUTICS INC | 3,477,051 | 78,512,000 | 3.27% | ||
| 10 | THERMO FISHER SCIENTIFIC INC | 590,036 | 76,563,000 | 3.19% | ||
| 11 | VERTEX PHARMACEUT | 598,800 | 73,940,000 | 3.08% | ||
| 12 | AMICUS THERAPEUTICS INC | 5,004,322 | 70,811,000 | 2.95% | ||
| 13 | PFIZER INC | 1,828,538 | 61,311,000 | 2.56% | ||
| 14 | SEATTLE GENETICS INC | 1,262,075 | 61,084,000 | 2.55% | ||
| 15 | PORTOLA PHARMACEUTICALS INC | 1,169,130 | 53,254,000 | 2.22% | ||
| 16 | ALLERGAN PLC | 161,031 | 48,866,000 | 2.04% | ||
| 17 | INTERCEPT PHARMACEUTICAL | 177,647 | 42,880,000 | 1.79% | ||
| 18 | TETRAPHASE PHARMACEUTICALS I COM | 893,076 | 42,368,000 | 1.77% | ||
| 19 | MEDTRONIC PLC | 519,829 | 38,519,000 | 1.61% | ||
| 20 | ALDER BIOPHARMACEUTICALS INC | 682,736 | 36,165,000 | 1.51% | ||
| 21 | MERCK & CO INC | 613,842 | 34,946,000 | 1.46% | ||
| 22 | DEXCOM | 398,158 | 31,845,000 | 1.33% | ||
| 23 | ONCOMED PHARMACEUTICALS INC | 1,369,534 | 30,815,000 | 1.29% | ||
| 24 | UNITED THERAPEUTICS | 175,780 | 30,577,000 | 1.28% | ||
| 25 | ALIGN TECHNOLOGY INC | 473,522 | 29,695,000 | 1.24% | ||
| 26 | PTC THERAPEUTICS INC | 614,742 | 29,588,000 | 1.23% | ||
| 27 | RELYPSA INC | 842,030 | 27,863,000 | 1.16% | ||
| 28 | SHIRE PLC | 113,812 | 27,484,000 | 1.15% | ||
| 29 | ABBOTT LABS | 541,734 | 26,588,000 | 1.11% | ||
| 30 | MYLAN N V | 376,951 | 25,580,000 | 1.07% | ||
| 31 | ZS PHARMA INC | 465,839 | 24,405,000 | 1.02% | ||
| 32 | EDWARDS LIFESCIENCES CORP | 155,825 | 22,194,000 | 0.93% | ||
| 33 | CHIMERIX INC | 474,900 | 21,940,000 | 0.92% | ||
| 34 | CLOVIS ONCOLOGY INC | 246,952 | 21,702,000 | 0.91% | ||
| 35 | TEVA PHARMACEUTICAL INDS LTD | 359,832 | 21,266,000 | 0.89% | ||
| 36 | ACCELERON PHARMA | 652,084 | 20,632,000 | 0.86% | ||
| 37 | KARYOPHARM THERAPEUTICS INC COM | 712,968 | 19,400,000 | 0.81% | ||
| 38 | UNIQURE NV | 649,800 | 17,545,000 | 0.73% | ||
| 39 | INTUITIVE SURGICAL INC | 36,188 | 17,533,000 | 0.73% | ||
| 40 | NXSTAGE MED INC COM | 1,172,196 | 16,745,000 | 0.70% | ||
| 41 | IMMUNE DESIGN CORP COM | 810,390 | 16,735,000 | 0.70% | ||
| 42 | NOVARTIS A G | 168,505 | 16,571,000 | 0.69% | ||
| 43 | HCA HOLDINGS INC | 175,945 | 15,962,000 | 0.67% | ||
| 44 | INVITAE CORP | 929,765 | 13,835,000 | 0.58% | ||
| 45 | DR REDDYS LABS LTD | 247,714 | 13,704,000 | 0.57% | ||
| 46 | CIGNA CORPORATION | 83,052 | 13,454,000 | 0.56% | ||
| 47 | Heartware International, Inc. | 178,574 | 12,981,000 | 0.54% | ||
| 48 | TG THERAPEUTICS INC COM | 772,017 | 12,808,000 | 0.53% | ||
| 49 | NOVO-NORDISK A S | 217,475 | 11,909,000 | 0.50% | ||
| 50 | SAGENT PHARMACEUTICALS INC | 465,625 | 11,319,000 | 0.47% |
Portfolio data is normalized using SEC Form 13F filings, including the Original 13F-HR (0001104659-15-059367, filed 2015.08.13).
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
