| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | VIVO CAPITAL, LLC | 5,573,319 | 22,460,000 | 23.64% | ||
| 2 | Nantahala Capital Management, LLC | 5,545,543 | 22,349,000 | 23.53% | ||
| 3 | FMR LLC | 2,133,282 | 8,597,000 | 9.05% | ||
| 4 | BlackRock Institutional Trust Company, N.A. | 1,260,155 | 5,078,000 | 5.35% | ||
| 5 | BAILLIE GIFFORD & CO | 1,185,133 | 4,777,000 | 5.03% | ||
| 6 | Opaleye Management Inc. | 1,178,500 | 4,749,000 | 5.00% | ||
| 7 | VANGUARD GROUP INC | 965,982 | 3,893,000 | 4.10% | ||
| 8 | BlackRock Fund Advisors | 876,101 | 3,531,000 | 3.72% | ||
| 9 | RENAISSANCE TECHNOLOGIES LLC | 838,800 | 3,380,000 | 3.56% | ||
| 10 | WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC | 670,383 | 2,702,000 | 2.84% | ||
| 11 | Granite Investment Partners, LLC | 375,805 | 1,515,000 | 1.59% | ||
| 12 | STATE STREET CORP | 373,655 | 1,504,000 | 1.58% | ||
| 13 | NORTHERN TRUST CORP | 347,068 | 1,399,000 | 1.47% | ||
| 14 | BRIDGEWAY CAPITAL MANAGEMENT, LLC | 265,500 | 1,070,000 | 1.13% | ||
| 15 | PALISADE CAPITAL MANAGEMENT, LP | 246,000 | 991,000 | 1.04% | ||
| 16 | GEODE CAPITAL MANAGEMENT, LLC | 189,435 | 763,000 | 0.80% | ||
| 17 | Spark Investment Management LLC | 151,600 | 610,000 | 0.64% | ||
| 18 | ESSEX INVESTMENT MANAGEMENT CO LLC | 147,015 | 592,000 | 0.62% | ||
| 19 | BlackRock Investment Management, LLC | 123,762 | 499,000 | 0.53% | ||
| 20 | Bank of New York Mellon Corp | 117,756 | 475,000 | 0.50% | ||
| 21 | AXA S.A. | 105,675 | 426,000 | 0.45% | ||
| 22 | TIAA CREF INVESTMENT MANAGEMENT LLC | 103,482 | 417,000 | 0.44% | ||
| 23 | OXFORD ASSET MANAGEMENT LLP | 103,404 | 417,000 | 0.44% | ||
| 24 | STRS OHIO | 77,000 | 310,000 | 0.33% | ||
| 25 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 70,198 | 283,000 | 0.30% | ||
| 26 | DIMENSIONAL FUND ADVISORS LP | 65,695 | 265,000 | 0.28% | ||
| 27 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 55,370 | 224,000 | 0.24% | ||
| 28 | TEACHERS ADVISORS, LLC | 52,753 | 213,000 | 0.22% | ||
| 29 | MENTA CAPITAL LLC | 39,878 | 161,000 | 0.17% | ||
| 30 | NEW YORK STATE COMMON RETIREMENT FUND | 34,400 | 139,000 | 0.15% | ||
| 31 | RHUMBLINE ADVISERS | 30,458 | 123,000 | 0.13% | ||
| 32 | MANUFACTURERS LIFE INSURANCE COMPANY, THE | 28,751 | 116,000 | 0.12% | ||
| 33 | BANK OF AMERICA CORP /DE/ | 25,095 | 101,000 | 0.11% | ||
| 34 | BLAIR WILLIAM & CO/IL | 24,922 | 100,000 | 0.11% | ||
| 35 | TFS CAPITAL LLC | 24,097 | 97,000 | 0.10% | ||
| 36 | DEUTSCHE BANK AG\ | 21,743 | 86,000 | 0.09% | ||
| 37 | Nationwide Fund Advisors | 20,988 | 85,000 | 0.09% | ||
| 38 | AMERICAN INTERNATIONAL GROUP, INC. | 19,272 | 77,666 | 0.08% | ||
| 39 | GOLDMAN SACHS GROUP INC | 16,937 | 68,000 | 0.07% | ||
| 40 | JACOBS LEVY EQUITY MANAGEMENT, INC | 16,629 | 67,000 | 0.07% | ||
| 41 | CREDIT SUISSE AG/ | 15,043 | 61,000 | 0.06% | ||
| 42 | STIFEL FINANCIAL CORP | 10,000 | 40,000 | 0.04% | ||
| 43 | BLACKROCK ADVISORS LLC | 9,569 | 39,000 | 0.04% | ||
| 44 | BlackRock Finance, Inc. | 6,710 | 27,000 | 0.03% | ||
| 45 | Legal & General Group Plc | 6,312 | 26,000 | 0.03% | ||
| 46 | WELLS FARGO & COMPANY/MN | 5,130 | 21,000 | 0.02% | ||
| 47 | MORGAN STANLEY | 4,520 | 18,000 | 0.02% | ||
| 48 | CITIGROUP INC | 3,372 | 14,000 | 0.01% | ||
| 49 | WOLVERINE TRADING LP /BD | 2,858 | 11,118 | 0.01% | ||
| 50 | BNP PARIBAS FINANCIAL MARKETS | 1,324 | 5,336 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
