| 1 |
Nantahala Capital Management, LLC |
5,561,082 |
24,691,000 |
23.56% |
|
|
| 2 |
VIVO CAPITAL, LLC |
5,294,825 |
23,509,000 |
22.43% |
|
|
| 3 |
FMR LLC |
2,133,282 |
9,472,000 |
9.04% |
|
|
| 4 |
BlackRock Institutional Trust Company, N.A. |
1,223,476 |
5,432,000 |
5.18% |
|
|
| 5 |
BAILLIE GIFFORD & CO |
1,185,133 |
5,262,000 |
5.02% |
|
|
| 6 |
Opaleye Management Inc. |
1,170,000 |
5,195,000 |
4.96% |
|
|
| 7 |
VANGUARD GROUP INC |
1,005,513 |
4,464,000 |
4.26% |
|
|
| 8 |
BlackRock Fund Advisors |
914,830 |
4,062,000 |
3.88% |
|
|
| 9 |
RENAISSANCE TECHNOLOGIES LLC |
872,200 |
3,873,000 |
3.70% |
|
|
| 10 |
WILLIAM BLAIR INVESTMENT MANAGEMENT, LLC |
716,160 |
3,180,000 |
3.03% |
|
|
| 11 |
STATE STREET CORP |
398,939 |
1,771,000 |
1.69% |
|
|
| 12 |
NORTHERN TRUST CORP |
357,821 |
1,589,000 |
1.52% |
|
|
| 13 |
BRIDGEWAY CAPITAL MANAGEMENT, LLC |
265,500 |
1,179,000 |
1.12% |
|
|
| 14 |
PALISADE CAPITAL MANAGEMENT, LP |
226,000 |
1,003,000 |
0.96% |
|
|
| 15 |
GEODE CAPITAL MANAGEMENT, LLC |
216,585 |
961,000 |
0.92% |
|
|
| 16 |
Spark Investment Management LLC |
206,500 |
916,000 |
0.87% |
|
|
| 17 |
Granite Investment Partners, LLC |
204,847 |
909,000 |
0.87% |
|
|
| 18 |
AXA S.A. |
153,201 |
680,000 |
0.65% |
|
|
| 19 |
ESSEX INVESTMENT MANAGEMENT CO LLC |
143,674 |
638,000 |
0.61% |
|
|
| 20 |
OXFORD ASSET MANAGEMENT LLP |
139,364 |
619,000 |
0.59% |
|
|
| 21 |
BlackRock Investment Management, LLC |
123,639 |
549,000 |
0.52% |
|
|
| 22 |
Bank of New York Mellon Corp |
114,388 |
507,000 |
0.48% |
|
|
| 23 |
STRS OHIO |
104,707 |
464,000 |
0.44% |
|
|
| 24 |
TIAA CREF INVESTMENT MANAGEMENT LLC |
103,482 |
459,000 |
0.44% |
|
|
| 25 |
CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM |
70,898 |
315,000 |
0.30% |
|
|
| 26 |
CHARLES SCHWAB INVESTMENT MANAGEMENT INC |
55,370 |
246,000 |
0.23% |
|
|
| 27 |
TEACHERS ADVISORS, LLC |
52,753 |
234,000 |
0.22% |
|
|
| 28 |
MILLENNIUM MANAGEMENT LLC |
47,251 |
210,000 |
0.20% |
|
|
| 29 |
ALAMBIC INVESTMENT MANAGEMENT, L.P. |
39,762 |
177,000 |
0.17% |
|
|
| 30 |
RHUMBLINE ADVISERS |
35,558 |
158,000 |
0.15% |
|
|
| 31 |
NEW YORK STATE COMMON RETIREMENT FUND |
34,400 |
153,000 |
0.15% |
|
|
| 32 |
JACOBS LEVY EQUITY MANAGEMENT, INC |
33,329 |
148,000 |
0.14% |
|
|
| 33 |
DIMENSIONAL FUND ADVISORS LP |
32,866 |
146,000 |
0.14% |
|
|
| 34 |
Campbell & CO Investment Adviser LLC |
31,619 |
140,000 |
0.13% |
|
|
| 35 |
MENTA CAPITAL LLC |
31,095 |
138,000 |
0.13% |
|
|
| 36 |
BLAIR WILLIAM & CO/IL |
27,782 |
123,000 |
0.12% |
|
|
| 37 |
WELLS FARGO & COMPANY/MN |
26,279 |
117,000 |
0.11% |
|
|
| 38 |
MANUFACTURERS LIFE INSURANCE COMPANY, THE |
25,861 |
115,000 |
0.11% |
|
|
| 39 |
DEUTSCHE BANK AG\ |
22,015 |
97,000 |
0.09% |
|
|
| 40 |
BANK OF AMERICA CORP /DE/ |
21,303 |
94,000 |
0.09% |
|
|
| 41 |
Nationwide Fund Advisors |
20,988 |
93,000 |
0.09% |
|
|
| 42 |
ACROSPIRE INVESTMENT MANAGEMENT LLC |
20,141 |
89,000 |
0.08% |
|
|
| 43 |
AMERICAN INTERNATIONAL GROUP, INC. |
19,301 |
85,696 |
0.08% |
|
|
| 44 |
GOLDMAN SACHS GROUP INC |
18,371 |
82,000 |
0.08% |
|
|
| 45 |
CREDIT SUISSE AG/ |
13,239 |
59,000 |
0.06% |
|
|
| 46 |
STATE BOARD OF ADMINISTRATION OF FLORIDA RETIREMENT SYSTEM |
13,218 |
59,000 |
0.06% |
|
|
| 47 |
BLACKROCK ADVISORS LLC |
12,335 |
55,000 |
0.05% |
|
|
| 48 |
FIRST QUADRANT LLC/CA |
11,747 |
52,000 |
0.05% |
|
|
| 49 |
GUGGENHEIM CAPITAL LLC |
11,558 |
51,000 |
0.05% |
|
|
| 50 |
MORGAN STANLEY |
10,639 |
47,000 |
0.04% |
|
|
