| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | FMR LLC | 6,364,630 | 271,260,000 | 12.58% | ||
| 2 | WELLINGTON MANAGEMENT GROUP LLP | 6,193,354 | 263,961,000 | 12.24% | ||
| 3 | Temasek Holdings (Private) Ltd | 5,833,568 | 248,627,000 | 11.53% | ||
| 4 | VANGUARD GROUP INC | 3,065,969 | 130,672,000 | 6.06% | ||
| 5 | BlackRock Fund Advisors | 1,902,381 | 81,079,000 | 3.76% | ||
| 6 | STATE STREET CORP | 1,297,428 | 55,292,000 | 2.56% | ||
| 7 | FRANKLIN RESOURCES INC | 1,234,701 | 52,623,000 | 2.44% | ||
| 8 | EAGLE ASSET MANAGEMENT INC | 1,234,603 | 52,618,000 | 2.44% | ||
| 9 | MPM ASSET MANAGEMENT LLC | 1,220,672 | 52,025,000 | 2.41% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 1,217,560 | 51,892,000 | 2.41% | ||
| 11 | CITADEL ADVISORS LLC | 1,195,716 | 50,961,000 | 2.36% | ||
| 12 | SECTORAL ASSET MANAGEMENT INC | 1,088,118 | 46,376,000 | 2.15% | ||
| 13 | MILLENNIUM MANAGEMENT LLC | 1,058,315 | 45,105,000 | 2.09% | ||
| 14 | ORBIMED ADVISORS LLC | 984,700 | 41,968,000 | 1.95% | ||
| 15 | JPMORGAN CHASE & CO | 920,405 | 39,227,000 | 1.82% | ||
| 16 | ALPS ADVISORS INC | 82,275 | 35,066,000 | 1.63% | ||
| 17 | Redmile Group, LLC | 769,641 | 32,802,000 | 1.52% | ||
| 18 | JENNISON ASSOCIATES LLC | 655,018 | 27,917,000 | 1.29% | ||
| 19 | CITIGROUP INC | 600,721 | 25,603,000 | 1.19% | ||
| 20 | NORTHERN TRUST CORP | 545,140 | 23,233,000 | 1.08% | ||
| 21 | Polar Capital LLP | 532,987 | 22,716,000 | 1.05% | ||
| 22 | Cormorant Asset Management, LP | 500,000 | 21,310,000 | 0.99% | ||
| 23 | EVENTIDE ASSET MANAGEMENT, LLC | 479,900 | 20,453,000 | 0.95% | ||
| 24 | NORGES BANK | 421,100 | 17,947,000 | 0.83% | ||
| 25 | PRICE T ROWE ASSOCIATES INC /MD/ | 394,479 | 16,813,000 | 0.78% | ||
| 26 | MARSHALL WACE, LLP | 387,451 | 16,513,000 | 0.77% | ||
| 27 | GEODE CAPITAL MANAGEMENT, LLC | 359,245 | 15,311,000 | 0.71% | ||
| 28 | DEUTSCHE BANK AG\ | 357,161 | 15,220,000 | 0.71% | ||
| 29 | ALLIANCEBERNSTEIN L.P. | 342,298 | 14,589,000 | 0.68% | ||
| 30 | HIGHLAND CAPITAL MANAGEMENT LP | 337,000 | 14,363,000 | 0.67% | ||
| 31 | DEERFIELD MANAGEMENT COMPANY, L.P. | 329,837 | 14,058,000 | 0.65% | ||
| 32 | Tourbillon Capital Partners, L.P. | 286,420 | 12,207,000 | 0.57% | ||
| 33 | WELLS FARGO & COMPANY/MN | 283,377 | 12,078,000 | 0.56% | ||
| 34 | VOYA INVESTMENT MANAGEMENT LLC | 280,801 | 11,968,000 | 0.55% | ||
| 35 | Bank of New York Mellon Corp | 265,641 | 11,322,000 | 0.52% | ||
| 36 | FRED ALGER MANAGEMENT, LLC | 241,541 | 10,294,000 | 0.48% | ||
| 37 | AXA S.A. | 234,921 | 10,012,000 | 0.46% | ||
| 38 | PUTNAM INVESTMENTS LLC | 224,289 | 9,559,000 | 0.44% | ||
| 39 | MORGAN STANLEY | 219,095 | 9,338,000 | 0.43% | ||
| 40 | GAM Holding AG | 212,793 | 9,068,000 | 0.42% | ||
| 41 | UBS AM, a distinct business unit of UBS ASSET MANAGEMENT AMERICAS LLC | 206,061 | 8,782,000 | 0.41% | ||
| 42 | Artisan Partners Limited Partnership | 200,973 | 8,565,000 | 0.40% | ||
| 43 | BBT Capital Management, LLC | 200,000 | 8,524,000 | 0.40% | ||
| 44 | Invesco Ltd. | 194,842 | 8,304,000 | 0.38% | ||
| 45 | EMERALD MUTUAL FUND ADVISERS TRUST | 192,264 | 8,194,000 | 0.38% | ||
| 46 | EMERALD ADVISERS, LLC | 190,388 | 8,114,000 | 0.38% | ||
| 47 | Fernwood Investment Management, LLC | 190,011 | 8,098,000 | 0.38% | ||
| 48 | TIAA CREF INVESTMENT MANAGEMENT LLC | 188,083 | 8,016,000 | 0.37% | ||
| 49 | BANK OF AMERICA CORP /DE/ | 187,682 | 8,000,000 | 0.37% | ||
| 50 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 162,787 | 6,938,000 | 0.32% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
