| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Broadfin Capital, LLC | 300,000 | 3,240,000 | 20.64% | ||
| 2 | BAKER BROS. ADVISORS LP | 221,631 | 2,394,000 | 15.25% | ||
| 3 | FMR LLC | 213,573 | 2,307,000 | 14.70% | ||
| 4 | Belmont Global Advisors, Inc. | 185,000 | 1,998,000 | 12.73% | ||
| 5 | Informed Momentum Co LLC | 149,143 | 1,611,000 | 10.27% | ||
| 6 | Iguana Healthcare Management, LLC | 112,500 | 1,215,000 | 7.74% | ||
| 7 | Trellus Management Company, LLC | 46,300 | 500,000 | 3.19% | ||
| 8 | RUSSELL FRANK CO/ | 38,497 | 416,000 | 2.65% | ||
| 9 | Spark Investment Management LLC | 27,800 | 300,000 | 1.91% | ||
| 10 | RENAISSANCE TECHNOLOGIES LLC | 27,400 | 296,000 | 1.89% | ||
| 11 | TOCQUEVILLE ASSET MANAGEMENT L.P. | 26,725 | 289,000 | 1.84% | ||
| 12 | JANE STREET GROUP, LLC | 20,381 | 220,000 | 1.40% | ||
| 13 | CREDIT SUISSE AG/ | 18,437 | 199,000 | 1.27% | ||
| 14 | GEODE CAPITAL MANAGEMENT, LLC | 11,264 | 121,000 | 0.77% | ||
| 15 | CITIGROUP INC | 11,225 | 121,000 | 0.77% | ||
| 16 | TANG CAPITAL MANAGEMENT LLC | 11,219 | 121,000 | 0.77% | ||
| 17 | BANK OF MONTREAL /CAN/ | 10,000 | 108,000 | 0.69% | ||
| 18 | MORGAN STANLEY | 9,050 | 98,000 | 0.62% | ||
| 19 | PANAGORA ASSET MANAGEMENT INC | 6,208 | 67,000 | 0.43% | ||
| 20 | WELLS FARGO & COMPANY/MN | 4,250 | 46,000 | 0.29% | ||
| 21 | WFG Advisors, LP | 1,339 | 14,000 | 0.09% | ||
| 22 | DEUTSCHE BANK AG\ | 600 | 6,000 | 0.04% | ||
| 23 | Tower Research Capital LLC (TRC) | 542 | 6,000 | 0.04% | ||
| 24 | UBS AG | 88 | 1,000 | 0.01% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
