| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | Camber Capital Management LP | 12,000,000 | 11,756,000 | 23.37% | ||
| 2 | Abingworth LLP | 8,087,486 | 7,847,000 | 15.60% | ||
| 3 | ORACLE INVESTMENT MANAGEMENT INC | 5,181,444 | 5,076,000 | 10.09% | ||
| 4 | D. E. Shaw & Co., Inc. | 3,505,655 | 3,434,000 | 6.83% | ||
| 5 | MILLENNIUM MANAGEMENT LLC | 3,085,889 | 3,023,000 | 6.01% | ||
| 6 | Visium Asset Management, LP | 3,000,000 | 2,940,000 | 5.84% | ||
| 7 | Broadfin Capital, LLC | 2,233,746 | 2,188,000 | 4.35% | ||
| 8 | AMERIPRISE FINANCIAL INC | 1,671,547 | 1,639,000 | 3.26% | ||
| 9 | PRESCOTT GROUP CAPITAL MANAGEMENT, L.L.C. | 1,405,000 | 1,376,000 | 2.74% | ||
| 10 | ALLIANCEBERNSTEIN L.P. | 1,236,520 | 1,212,000 | 2.41% | ||
| 11 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 1,102,105 | 1,080,000 | 2.15% | ||
| 12 | TURNER INVESTMENTS LLC | 875,390 | 858,000 | 1.71% | ||
| 13 | CITADEL ADVISORS LLC | 789,976 | 774,000 | 1.54% | ||
| 14 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 631,900 | 619,000 | 1.23% | Put | |
| 15 | GLG Partners LP | 518,664 | 508,000 | 1.01% | ||
| 16 | Healthcare Value Capital, LLC | 500,000 | 490,000 | 0.97% | Call | |
| 17 | Artal Group S.A. | 500,000 | 490,000 | 0.97% | Call | |
| 18 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 470,500 | 485,000 | 0.96% | ||
| 19 | UBS Group AG | 406,441 | 398,000 | 0.79% | ||
| 20 | ORBIMED ADVISORS LLC | 400,000 | 392,000 | 0.78% | ||
| 21 | DEUTSCHE BANK AG\ | 321,554 | 315,000 | 0.63% | ||
| 22 | GOLDMAN SACHS GROUP INC | 321,847 | 315,000 | 0.63% | ||
| 23 | J. Goldman & Co LP | 287,500 | 282,000 | 0.56% | ||
| 24 | MORGAN STANLEY | 284,997 | 280,000 | 0.56% | ||
| 25 | CREDIT SUISSE AG/ | 223,335 | 219,000 | 0.44% | ||
| 26 | COMMERZBANK AKTIENGESELLSCHAFT /FI | 200,828 | 197,000 | 0.39% | ||
| 27 | State of New Jersey Common Pension Fund D | 187,000 | 183,000 | 0.36% | ||
| 28 | CITIGROUP INC | 165,675 | 162,000 | 0.32% | ||
| 29 | BASSO CAPITAL MANAGEMENT, L.P. | 151,400 | 148,000 | 0.29% | Call | |
| 30 | Jefferies Group LLC | 128,100 | 126,000 | 0.25% | Call | |
| 31 | JANE STREET GROUP, LLC | 124,781 | 122,000 | 0.24% | ||
| 32 | BCWM, LLC | 12,000 | 118,000 | 0.23% | ||
| 33 | Virtu KCG Holdings LLC | 114,166 | 112,000 | 0.22% | ||
| 34 | Paloma Partners Management Co | 111,566 | 109,000 | 0.22% | ||
| 35 | STATE STREET CORP | 101,445 | 99,000 | 0.20% | ||
| 36 | Jefferies Group LLC | 90,500 | 89,000 | 0.18% | ||
| 37 | DekaBank Deutsche Girozentrale | 88,700 | 85,000 | 0.17% | ||
| 38 | HSBC HOLDINGS PLC | 68,569 | 67,000 | 0.13% | ||
| 39 | Spot Trading L.L.C | 66,200 | 65,000 | 0.13% | Call | |
| 40 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 58,100 | 57,000 | 0.11% | Call | |
| 41 | CARL DOMINO INC | 46,000 | 45,000 | 0.09% | ||
| 42 | UBS Group AG | 46,000 | 45,000 | 0.09% | Call | |
| 43 | LAZARD ASSET MANAGEMENT LLC | 42,094 | 41,000 | 0.08% | ||
| 44 | Airain ltd | 37,597 | 37,000 | 0.07% | ||
| 45 | NORTHERN TRUST CORP | 34,271 | 34,000 | 0.07% | ||
| 46 | GEODE CAPITAL MANAGEMENT, LLC | 30,309 | 29,000 | 0.06% | ||
| 47 | J.P. Morgan Private Wealth Advisors LLC | 26,500 | 26,000 | 0.05% | ||
| 48 | GOLDMAN SACHS GROUP INC | 26,100 | 26,000 | 0.05% | Put | |
| 49 | AMERICAN INTERNATIONAL GROUP, INC. | 25,779 | 25,255 | 0.05% | ||
| 50 | Private Advisor Group, LLC | 22,600 | 22,000 | 0.04% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
