| # | % | |||||
|---|---|---|---|---|---|---|
| 1 | PUTNAM INVESTMENTS LLC | 20,546,501 | 119,992,000 | 14.72% | ||
| 2 | Sarissa Capital Management LP | 12,850,000 | 75,044,000 | 9.20% | ||
| 3 | VANGUARD GROUP INC | 11,880,653 | 69,384,000 | 8.51% | ||
| 4 | WESTFIELD CAPITAL MANAGEMENT CO LP | 9,633,464 | 56,259,000 | 6.90% | ||
| 5 | BlackRock Fund Advisors | 8,228,791 | 48,056,000 | 5.89% | ||
| 6 | FMR LLC | 7,572,846 | 44,225,000 | 5.42% | ||
| 7 | ADAGE CAPITAL PARTNERS GP, L.L.C. | 7,000,000 | 40,880,000 | 5.01% | ||
| 8 | STATE STREET CORP | 6,242,593 | 36,458,000 | 4.47% | ||
| 9 | Camber Capital Management LP | 5,533,118 | 32,313,000 | 3.96% | ||
| 10 | BlackRock Institutional Trust Company, N.A. | 4,323,671 | 25,250,000 | 3.10% | ||
| 11 | PointState Capital LP | 3,500,000 | 20,440,000 | 2.51% | ||
| 12 | Palo Alto Investors LP | 2,231,717 | 13,033,000 | 1.60% | ||
| 13 | NORTHERN TRUST CORP | 2,071,567 | 12,099,000 | 1.48% | ||
| 14 | OppenheimerFunds, Inc. | 1,852,920 | 10,821,000 | 1.33% | ||
| 15 | NORGES BANK | 1,665,993 | 9,729,000 | 1.19% | ||
| 16 | Elk Creek Partners, LLC | 1,348,195 | 7,873,000 | 0.97% | ||
| 17 | Opaleye Management Inc. | 1,310,000 | 7,650,000 | 0.94% | ||
| 18 | Alberta Investment Management Corp | 1,254,286 | 7,325,000 | 0.90% | ||
| 19 | GENERAL AMERICAN INVESTORS CO INC | 1,200,000 | 7,008,000 | 0.86% | ||
| 20 | GEODE CAPITAL MANAGEMENT, LLC | 1,187,523 | 6,935,000 | 0.85% | ||
| 21 | HBK INVESTMENTS L P | 1,122,100 | 6,553,000 | 0.80% | ||
| 22 | BNP Paribas Asset Management Holding S.A. | 951,068 | 5,554,000 | 0.68% | ||
| 23 | AMERIPRISE FINANCIAL INC | 925,520 | 5,404,000 | 0.66% | ||
| 24 | Bank of New York Mellon Corp | 884,684 | 5,166,000 | 0.63% | ||
| 25 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 884,400 | 5,165,000 | 0.63% | Call | |
| 26 | HighVista Strategies LLC | 850,000 | 4,964,000 | 0.61% | ||
| 27 | GUGGENHEIM CAPITAL LLC | 753,679 | 4,401,000 | 0.54% | ||
| 28 | TIAA CREF INVESTMENT MANAGEMENT LLC | 745,633 | 4,354,000 | 0.53% | ||
| 29 | PRICE MICHAEL F | 716,500 | 4,184,000 | 0.51% | ||
| 30 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 716,402 | 4,184,000 | 0.51% | ||
| 31 | Granite Point Capital Management, L.P. | 634,772 | 3,707,000 | 0.45% | ||
| 32 | JS Capital Management LLC | 605,000 | 3,533,000 | 0.43% | ||
| 33 | GOLDMAN SACHS GROUP INC | 598,526 | 3,496,000 | 0.43% | ||
| 34 | Dynamic Capital Management Ltd | 583,841 | 3,410,000 | 0.42% | ||
| 35 | CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 577,836 | 3,375,000 | 0.41% | ||
| 36 | BlackRock Investment Management, LLC | 561,742 | 3,281,000 | 0.40% | ||
| 37 | SUSQUEHANNA INTERNATIONAL GROUP, LLP | 534,900 | 3,124,000 | 0.38% | Put | |
| 38 | CREDIT SUISSE AG/ | 517,562 | 3,023,000 | 0.37% | ||
| 39 | BELLEVUE ASSET MANAGEMENT AG | 495,000 | 2,891,000 | 0.35% | ||
| 40 | MILLENNIUM MANAGEMENT LLC | 472,248 | 2,758,000 | 0.34% | ||
| 41 | PERCEPTIVE ADVISORS LLC | 450,000 | 2,628,000 | 0.32% | ||
| 42 | Rhenman & Partners Asset Management AB | 430,000 | 2,511,000 | 0.31% | ||
| 43 | Family Manage LLC | 422,765 | 2,469,000 | 0.30% | ||
| 44 | PARAMETRIC PORTFOLIO ASSOCIATES LLC | 402,812 | 2,352,000 | 0.29% | ||
| 45 | CALIFORNIA PUBLIC EMPLOYEES RETIREMENT SYSTEM | 385,800 | 2,253,000 | 0.28% | ||
| 46 | ROYCE & ASSOCIATES LP | 375,352 | 2,192,000 | 0.27% | ||
| 47 | JPMORGAN CHASE & CO | 363,630 | 2,124,000 | 0.26% | ||
| 48 | ALLIANCEBERNSTEIN L.P. | 309,785 | 1,809,000 | 0.22% | ||
| 49 | CALIFORNIA STATE TEACHERS RETIREMENT SYSTEM | 305,276 | 1,783,000 | 0.22% | ||
| 50 | TEACHERS ADVISORS, LLC | 300,670 | 1,756,000 | 0.22% |
From 2023-01-03 onward, the SEC requires values to be reported in nearest dollars. Earlier filings reported values in thousands; therefore, positions shown as $0 in older filings may represent actual values between $0–$999.
